CIVIL SOCIETY AS A THREAT TO DEMOCRACY: ORGANIZATIONAL BASES OF THE POPULIST COUNTERREVOLUTION IN POLAND. CES Open Forum Series 2019-2020

A distinctive trajectory of civil society transformation in Poland has provided organizational foundations for the cultural and political polarization and facilitated country’s recent turn towards authoritarianism. Developments in Poland suggest that the reigning notion of the inherent virtuousness of civil society, its unquestionably beneficial role in strengthening democracy and assumed liberal preferences of civil society actors need to be reassessed. Consequently, I argue that the particular organizational configuration of civil society, its sectoral composition, normative orientation of its actors and prevailing cleavages can either strengthen or undermine democracy. Since country’s transition to democracy in 1989, Polish civil society has evolved into an organizational form that can be described as “pillarized civil society.” While historically pillarization of civil society was considered to be a peculiar phenomenon in the Low Countries in the XIX century, this form of civil society organization has become increasingly common in contemporary democratic societies with dividing boundaries shaped by identitybased cleavages (religious, ethnic, political). The presence of vertically segmented civil society enables extreme cultural and political polarization and facilitated mobilization of far-right, nationalist and conservative religious movements. In Poland, pillarized civil society affect electoral fortune of liberal parties, provides support for anti-liberal and anti-European policies of the current Polish government dominated by the Law and Justice party as well as defines political conflicts and protest politics

The Weakness of Post-Communist Civil Society Reassessed. CES Papers - Open Forum #11, 2012

During the last two decades, scholars from a variety of disciplines have argued that civil society is structurally deficient in post-communist countries. Yet why have the seemingly strong, active and mobilized civic movements of the transition period become so weak after democracy was established? And why have there been diverging political trajectories across the post-communist space if civil society structures were universally weak? This paper uses a wide range of data from various available sources to show that civil societies in Central and Eastern European countries are not as feeble as is commonly assumed. Some post-communist countries possess vigorous public spheres, and active civil society organizations strongly connected to transnational civic networks able to shape domestic policies. Following the calls by Anheier (2004) and Bernhard and Karakoç (2007) we adopt a multidimensional approach to the measurement of civil society. In a series of cross-section timeseries models, we show that our broader measures of civic and social institutions are able to predict the diverging transition paths among post-communist regimes, and in particular the growing gap between democratic East Central Europe and the increasingly authoritarian post-Soviet space

The effects of complexity, accuracy, and fluency on communicative adequacy in oral task performance

Communicative adequacy is a key construct in second language research, as the primary goal of most language learners is to communicate successfully in real-world situations. Nevertheless, little is known about what linguistic features contribute to communicatively adequate speech. This study fills this gap by investigating the extent to which complexity, accuracy, and fluency (CAF) predict adequacy, and whether proficiency and task type moderate these relationships. In all, 20 native speakers and 80 second language users from four proficiency levels performed five tasks. Speech samples were rated for adequacy and coded for a range of CAF indices. Filled pause frequency, a feature of breakdown fluency, emerged as the strongest predictor of adequacy. Predictors with significant but smaller effects included indices of all three CAF dimensions: linguistic complexity (lexical diversity, overall syntactic complexity, syntactic complexity by subordination, and frequency of conjoined clauses), accuracy (general accuracy and accuracy of connectors), and fluency (silent pause frequency and speed fluency). For advanced speakers, incidence of false starts also emerged as predicting communicatively adequate speech. Task type did not influence the link between linguistic features and adequacy

Divergent evolution of protein conformational dynamics in dihydrofolate reductase.

Molecular evolution is driven by mutations, which may affect the fitness of an organism and are then subject to natural selection or genetic drift. Analysis of primary protein sequences and tertiary structures has yielded valuable insights into the evolution of protein function, but little is known about the evolution of functional mechanisms, protein dynamics and conformational plasticity essential for activity. We characterized the atomic-level motions across divergent members of the dihydrofolate reductase (DHFR) family. Despite structural similarity, Escherichia coli and human DHFRs use different dynamic mechanisms to perform the same function, and human DHFR cannot complement DHFR-deficient E. coli cells. Identification of the primary-sequence determinants of flexibility in DHFRs from several species allowed us to propose a likely scenario for the evolution of functionally important DHFR dynamics following a pattern of divergent evolution that is tuned by cellular environment

Rapid determination of salbutamol in pharmaceutical preparations by chiral capillary electrophoresis

A fast and simple method of chiral capillary electrophoresis (CE) has been applied to the analysis of salbutamol in different pharmaceutical preparations. Using of a 25 mM acetate buffer (pH 5.0), containing 13.1 mg/mL carboxymethyl- -cyclodextrin (CM- -\ud CD), an applied voltage of 20 kV and a temperature of 25 C, the enantiomers of salbutamol could be separated in about 2 min. Three different pharmaceutical preparations (two syrups, one oral solution, and two kind of tablets) containing a racemate of salbutamol\ud were injected directly in the CE system, following dilution in dimethyl sulfoxide\ud (DMSO). Appreciable differences in the retention times were observed for salbutamol enantiomers in the different formulations studied, which were attributed to the effect of the matrix components on the electrophoretic mobility. The standard addition method\ud was used for the calibration due to the existence of matrix interferences. Finally, the stability of the enantiomers of salbutamol in the oral solution was studied calculating the enantiomeric ratio values when the solution was injected immediately after being opened in the first case and after being opened and stored in the fridge for two months in the second case

Accumulation of dibenzocyclooctadiene lignans in agar cultures and in stationary and agitated liquid cultures of Schisandra chinensis (Turcz.) Baill

Schisandra chinensis plant in vitro cultures were maintained on Murashige and Skoog (MS) medium supplemented with 3 mg/l 6-benzyladenine (BA) and 1 mg/l 1-naphthaleneacetic acid (NAA) in an agar system and also in two different liquid systems: stationary and agitated. Liquid cultures were grown in batch (30 and 60 days) and fed-batch modes. In the methanolic extracts from lyophilized biomasses and in the media, quantification of fourteen dibenzocyclooctadiene lignans identified based on co-chromatography with authentic standards using high-performance liquid chromatography with diode array detection (HPLC-DAD) and/or liquid chromatography with diode array detection and electrospray ionization mass spectrometry (LC-DAD-ESI-MS) methods. For comparison purposes, phytochemical analyses were performed of lignans in the leaves and fruits of the parent plant. The main lignans detected in the biomass extracts from all the tested systems were schisandrin (max. 65.62 mg/100 g dry weight (DW)), angeloyl-/tigloylgomisin Q (max. 49.73 mg/100 g DW), deoxyschisandrin (max. 43.65 mg/100 g DW), and gomisin A (max. 34.36 mg/100 g DW). The highest total amounts of lignans in the two tested stationary systems were found in extracts from the biomass harvested after 30 days of batch cultivation: 237.86 mg/100 g DW and 274.65 mg/100 g DW, respectively. In the agitated culture, the total content reached a maximum value of 244.80 mg/100 g DW after 60 days of the fed-batch mode of cultivation. The lignans were not detected in the media. This is the first report which documents the potential usefulness of S. chinensis shoot cultures cultivated in liquid systems for practical purposes. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00253-015-7230-9) contains supplementary material, which is available to authorized users

Stalking influenza by vaccination with pre-fusion headless HA mini-stem.

Inaccuracies in prediction of circulating viral strain genotypes and the possibility of novel reassortants causing a pandemic outbreak necessitate the development of an anti-influenza vaccine with increased breadth of protection and potential for rapid production and deployment. The hemagglutinin (HA) stem is a promising target for universal influenza vaccine as stem-specific antibodies have the potential to be broadly cross-reactive towards different HA subtypes. Here, we report the design of a bacterially expressed polypeptide that mimics a H5 HA stem by protein minimization to focus the antibody response towards the HA stem. The HA mini-stem folds as a trimer mimicking the HA prefusion conformation. It is resistant to thermal/chemical stress, and it binds to conformation-specific, HA stem-directed broadly neutralizing antibodies with high affinity. Mice vaccinated with the group 1 HA mini-stems are protected from morbidity and mortality against lethal challenge by both group 1 (H5 and H1) and group 2 (H3) influenza viruses, the first report of cross-group protection. Passive transfer of immune serum demonstrates the protection is mediated by stem-specific antibodies. Furthermore, antibodies indudced by these HA stems have broad HA reactivity, yet they do not have antibody-dependent enhancement activity

Acquisition of the English Article System by Speakers of Polish in ESL and EFL Settings

This paper examines the second language (L2) developmental sequence of article acquisition by adult language learners in two different environments: English as a Second Language (ESL), and English as a Foreign Language (EFL). On the basis of an existing classification of English articles (a, the, zero), data on article usage were obtained from adult learners who were native speakers of Polish, a language that has no articles or article-like morphemes. Data analyses led to some limited conclusions about the order of acquisition of the English article system, and may contribute to a more detailed understanding of the nature of interlanguage representations

The Bilingual Brain

Increased understanding of the ways in which multiple languages are represented in bilingual speakers’ brains would undoubtedly advance several theoretical issues in areas such as language acquisition and performance theory. The progress of science forces linguists to draw upon relevant data from neurolinguistics and opens a new avenue for SLA researchers. This literature review will examine neurolinguistic models that have been proposed as an explanation for the coexistence of multiple languages in a single brain and the mechanisms of linguistic segregation. An overview of the study of language localization will be presented, followed by a discussion of neurolinguistic studies investigating the cerebral representation of language in bilinguals. A particular area of focus will be factors affecting language representation in the bilingual brain