New chemistry with gold-nitrogen complexes: synthesis and characterization of tetra-, tri-, and dinuclear gold(I) amidinate complexes. Oxidative-addition to the dinuclear gold(I) amidinate

Nitrogen ligands have been little studied with gold(I) and almost no chemistry has been described using anionic bridging nitrogen ligands. This dissertation concerns the impact of the bridging ligands amidinate, ArNHC(H)NAr, on the chemistry of gold(I) and, in particular, the effect of substituents on the molecular arrangement. The electronic vs. steric effect of the substituents on the molecular arrangement of gold(I) amidinates complexes is studied in detail. Tetra-, tri-, and dinuclear gold(I) amidinate complexes are synthesized and characterized using X-ray diffraction. Spectroscopic and electrochemical studies of the amidinate complexes are described. Catalytic studies suggest that gold amidinates and related gold nitrogen complexes are the best catalyst precursors for CO oxidation on TiO2 surface reported to date (87% conversion). The dinuclear gold(I) amidinate complex with a Auâ ¦Au distance of 2.711(3) Ã is rare. To our knowledge, there is only one other example of a symmetrical dinuclear gold(I) nitrogen complex. Oxidative-addition reactions to the dinuclear gold(I) complex, [Au2(2,6-Me2-form)2] are studied in detail and result in the formation of gold(II) complexes. The gold(II) amidinate complexes are the first formed with nitrogen ligands. The complexes are stable at room temperature. Mixed ligand tetranuclear gold(I) clusters and tetranuclear mixed Au-Ag metal clusters of pyrazolate and amidinate ligands are synthesized and characterized using Xray diffraction

USING MOBILE AUGMENTED REALITY TECHNOLOGIES IN ARCHITECTURAL EDUCATION

Effective applied research is based on close collaboration between research and industry. The teaching and learning methods used for decades in Architectural learning process should be reviewed taking into account habits of learning and the existing challenges provided by contemporary information technologies for a new generation of students. This paper introduces a pilot study based on using Augmented Reality (AR) as a new tool in architectural learning process. AR is an emerging technology which enables participants to interact with digital information embedded within the physical environment. Egyptian educational architectural institutions today are largely unaware of new concepts such as Augmented Reality opportunities for architectural practice, and the prototypes that are being developed by researchers worldwide. The paper goal is to present how it is very helpful to use such new advanced technology in architectural learning process. Testing its possibilities for graphical and spatial capabilities and recognition improvements for the first year architectural students in the Building Construction course, at the Department of Architecture, Menoufia University, Egypt. The case study was applied at the first semester of the academic year of 2015-2016

An Innovative algorithm framework for cardiovascular risk assessment based on ECG data

Background:Cardiovascular disease (CVD) is a primary universal physical problem, with conventional prediction systems frequently being persistent and expensive. Modern advancements in machine learning (ML)offer a hopeful option for accurate CVD risk assessment by leveraging multifaceted relations among diverse risk factors.Aim:Their search proposes a novel deep learning (DL) system, Dynamic Owl Search algorithm-driven Adaptive Long Short-Term Memory (DOS-ALSTM), to enhance cardiovascular risk prediction utilizing electrocardiogram (ECG) data.Method:The study utilizes ECG data from a diverse population group to train and assess the proposed model. Data is cleaned and normalized employing standard techniques to handle lost values and ensure reliability. Relevant features are extracted using statistical and signal processing technique to detain crucial features from the ECG data. The DOS-ALSTM system integrates a DOS optimization algorithm for optimized parameter regulation and ALSTM networks to detain sequential dependencies in ECG data for accurate risk prediction. The recognized method is evaluated using Python software.Result:The DOS-ALSTM system demonstrates superior performance with superioraccuracy of 99%, recall of 98%, F1-Score of 97.9% and Precision of 98.8% in CVD risk assessment compared to traditional method

Mental Health State Classification Using Facial Emotion Recognition and Detection

Analyzing and understanding emotion can help in various aspects, such as realizing one’s attitude, behavior, etc. By understanding one’s emotions, one's mental health state can be calculated, which can help in the medical field by classifying whether one is mentally stable or not. Facial Recognition is one of the many fields of computer vision that utilizes convolutional networks or Conv Nets to perform, train, and learn. Conv Nets and other machine learning algorithms have evolved to adapt better to larger datasets. One of the advancements in Conv Nets and machines is the introduction of various Conv architectures like VGGNet. Thus, this study will present a mental health state classification approach based on facial emotion recognition. The methodology comprises several interconnected components, including preprocessing, feature extraction using Principal Component Analysis (PCA) and VGGNet, and classification using Support Vector Machines (SVM) and Multilayer Perceptron (MLP). The FER2013 dataset tests multiple models’ performances, and the best model is employed in the mental health state classification. The best model, which combines Visual Geometry Group Network (VGGNet) feature extraction with SVM classification, achieved an accuracy of 66%, demonstrating the effectiveness of the proposed methodology. By leveraging facial emotion recognition and machine learning techniques, the study aims to develop an effective method

Comparison of Muscle Energy Techniques and Myofascial Release in Premenopausal Women with Fibromyalgia

Background and Purpose Fibromyalgia is characterized by idiopathic long-lasting pain that negatively impacts patients’ quality of life. Although many therapeutic interventions are available; treatment is still challenging due to the condition’s complexity. Therefore, comparative researches are required to decide which treatment is better to produce the best clinical decision for fibromyalgia. The purpose of this study was to compare the effect of ‘muscle energy technique and myofascial release’ on fibromyalgia patients. Materials and Methods In this randomized controlled trial, seventy-four women aged 30 to 45, with a body mass index ranging from 25 - 34.9 kg/m², were participated. They were assigned to either the ‘muscle energy technique or myofascial release’ group. Each treatment was conducted over four weeks, with three weekly sessions lasting 25 minutes each. Meanwhile, the ‘myofascial release’ group received treatment for 20 minutes, three times per week for the same duration. Outcome measures included ‘pain levels assessed via a visual analog scale, range of motion evaluated with a universal goniometer, and quality of life determined through the fibromyalgia impact questionnaire’. Results ‘Muscle energy technique and myofascial release’ showed a significant decrease (p<0.001) in cervical pain, low back pain, and fibromyalgia impact questionnaire score, and a significant increase (p<0.001) in cervical and trunk range of motion after treatment. The myofascial release group showed more significant decrease in cervical pain (p=0.002), low back pain (p=0.003), fibromyalgia impact questionnaire score (p=0.001), cervical left bending (p=0.007), and trunk extension (p=0.003), right bending (p=0.014), left bending (p=0.007), right rotation (p=0.009), and left rotation (p=0.007) than muscle energy technique group. Conclusion ‘Muscle energy technique and myofascial release’ is beneficial methods for fibromyalgia patients. However, myofascial release was more effective than muscle energy technique in improving pain, quality of life, and trunk range of motion

Opportunistic salpingectomy during hysterectomy for benign indications in women at low and high risk for ovarian cancer: a cross-sectional study

Objective Our study aims to evaluate the role of pathology evaluation of fallopian tubesduring hysterectomy for benign indications for the purpose ofearly detection of serous tubal intraepithelial carcinoma (STIC) in women at high and low risk for ovarian cancer. Material and methods This cross-sectional study was conducted at Minia Maternity University Hospital, Egypt, between June 2015 and December 2017. Our study included all women undergoing hysterectomy for benign conditions in the genital tract. Appropriate histories were taken, as well as physical exams, and laboratory and ultrasound evaluations were done prior to scheduling surgery. Abdominal hysterectomies including opportunistic salpingectomies were performed and the whole specimens including the tubal fimbria were sent to the pathology lab for histo-pathological examination. Results A total of 526 patients met inclusion criteria for this study. The mean age of the study participants was 49.75±8.95 years, the mean parity was 3.91±1.62 and the mean BMI was 24.21±2.38 Kg/m2. The most common surgical indications for hysterectomy were postmenopausal bleeding (34.6%), a clinically benign adnexal/pelvic mass (31.7%), and menorrhagia (24.7%). The fallopian tubes were found to have either no pathology or benign conditions in 500 out of the 526 patients. Among these patients, 56% had no pathologic abnormality. The most common benign conditions were paratubal cysts (25%), endometriosis (9%), torsion (2%) and hydrosalpinx (1%). STIC was identified in the fallopian tubes of 8 out of 526 patients. Conclusions Microscopic examination of the entire fimbriae from all patients regardless of the clinical context represents a novel method of early detection of sporadic tubal carcinoma, a putative precursor to advanced-stage pelvic cancer

Guidelines for the prevention, detection and management of the renal complications of COVID-19 in Africa

Africa trails the rest of the world in COVID-19 cases and deaths. However, as the pandemic spreads through the continent, we expect increases in community infection in the months ahead. Patients with kidney infection, especially those with end-stage kidney disease and those with kidney transplants, are at high risk for acquiring the disease and dying from it. While there is limited evidence for the benefit of interventions, we have the advantage of learning from the experiences of those in China, Europe and the Americas. This document sets forth guidance for dealing with our patients who have acute and chronic kidney disease, including those on renal replacement therapy and the staff involved in their care. Emphasis is placed on preparedness and prevention strategies. As evidence and experience accumulate, it is likely that updated guidance will be needed.L’Afrique suit le reste du monde en termes de nombre de cas et de décès dus à COVID-19. Cependant, alors que la pandémie se propage à travers le continent, nous prévoyons une augmentation de l’infection communautaire dans les mois à venir. Les patients atteints d’une maladie rénale, en particulier ceux atteints d’une maladie rénale chronique en phase terminale et ceux ayant subi une transplantation rénale, courent un risque élevé de contracter la maladie et d’en mourir. Bien que les preuves d’interventions soient limitées, nous avons l’avantage de tirer des enseignements des expériences de ceux qui se trouvent en Chine, en Europe et dans les Amériques. Ce document présente des conseils pour traiter nos patients atteints d’insuffisance rénale aiguë et chronique, y compris ceux sous thérapie de suppléance rénale et le personnel impliqué dans leurs soins. L’accent est mis sur les stratégies de préparation et de prévention. Au fur et à mesure que les preuves et l’expérience s’accumulent, il est probable que des directives actualisées seront nécessaires

Biliary fistula and late recurrence of liver hydatid cyst: Role of cysto-biliary communication: A prospective multicenter study

Background: Hydatid cyst disease (HCD) is common in certain locations. Surgery is associated with postoperative biliary fistula (POBF) and recurrence. The primary aim of this study was to identify whether occult cysto-biliary communication (CBC) can predict recurrent HCD. The secondary aim was to assess the role of cystic fluid bilirubin and alkaline phosphatase (ALP) levels in predicting POBF and recurrent HCD. Aim: To identify whether occult CBC can predict recurrent HCD. The secondary aim was to assess the role of cystic fluid bilirubin and ALP levels in predicting POBF and recurrent HCD. Methods: From September 2010 to September 2016, a prospective multicenter study was undertaken involving 244 patients with solitary primary superficial stage cystic echinococcosis 2 and cystic echinococcosis 3b HCD who underwent laparoscopic partial cystectomy with omentoplasty. Univariable logistic regression analysis assessed independent factors determining biliary complications and recurrence. Results: There was a highly statistically significant association (P ≤ 0.001) between cystic fluid biochemical indices and the development of biliary complications (of 16 patients with POBF, 15 patients had high cyst fluid bilirubin and ALP levels), where patients with high bilirubin-ALP levels were 3405 times more likely to have biliary complications. There was a highly statistically significant association (P ≤ 0.001) between biliary complications, biochemical indices, and the occurrence of recurrent HCD (of 30 patients with recurrent HCD, 15 patients had high cyst fluid bilirubin and ALP; all 16 patients who had POBF later developed recurrent HCD), where patients who developed biliary complications and high bilirubin-ALP were 244.6 and 214 times more likely to have recurrent hydatid cysts, respectively. Conclusion: Occult CBC can predict recurrent HCD. Elevated cyst fluid bilirubin and ALP levels predicted POBF and recurrent HCD

Intraoperative endomanometric laparoscopic Nissen fundoplication improves postoperative outcomes in large sliding hiatus hernia with severe gastroesophageal reflux disease. A retrospective cohort study

Background: Laparoscopic Nissen Fundoplication (LNF) is the gold standard surgical intervention for gastroesophageal reflux disease (GERD). LNF can be followed by recurrent symptoms or complications affecting patient satisfaction. The aim of this study is to assess the value of the intraoperative endomanometric evaluation of esophagogastric competence and pressure combined with LNF in patients with large sliding hiatus hernia (&gt; 5&nbsp;cm) with severe GERD (DeMeester score &gt;100). Materials and methods: This is a retrospective, multicenter cohort study. Baseline characteristics, postoperative dysphagia and gas bloat syndrome, recurrent symptoms, and satisfaction were collected from a prospectively maintained database. Outcomes analyzed included recurrent reflux symptoms, postoperative side effects, and satisfaction with surgery. Results: 360 patients were stratified into endomanometric LNF (180 patients, LNF+) and LNF alone (180 patients, LNF). Recurrent heartburn (3.9% vs. 8.3%) and recurrent regurgitation (2.2% vs. 5%) showed a lower incidence in the LNF+ group (P=0.012). Postoperative score III recurrent heartburn and score III regurgitations occurred in 0% vs. 3.3% and 0% vs. 2.8% cases in the LNF+ and LNF groups, respectively (P=0.005). Postoperative persistent dysphagia and gas bloat syndrome occurred in 1.75% vs. 5.6% and 0% vs. 3.9% of patients (P=0.001). Score III postoperative persistent dysphagia was 0% vs. 2.8% in the two groups (P=0.007). There was no redo surgery for dysphagia after LNF+. Patient satisfaction at the end of the study was 93.3% vs. 86.7% in both cohorts, respectively (P=0.05). Conclusions: Intraoperative high-resolution manometry (HRM) and endoscopic were feasible in all patients, and the outcomes were favorable from an effectiveness and safety standpoint

Side-specific factors for intraoperative hemodynamic instability in laparoscopic adrenalectomy for pheochromocytoma: a comparative study

Background: Adrenalectomy for pheochromocytoma (PHEO) is challenging because of the high risk of intraoperative hemodynamic instability (HDI). This study aimed to compare the incidence and risk factors of intraoperative HDI between laparoscopic left adrenalectomy (LLA) and laparoscopic right adrenalectomy (LRA). Methods: We retrospectively analyzed two hundred and seventy-one patients aged &gt; 18 years with unilateral benign PHEO of any size who underwent transperitoneal laparoscopic adrenalectomy at our hospitals between September 2016 and September 2023. Patients were divided into LRA (N = 122) and LLA (N = 149) groups. Univariate and multivariate logistic regression analyses were used to predict intraoperative HDI. In multivariate analysis for the prediction of HDI, right-sided PHEO, PHEO size, preoperative comorbidities, and preoperative systolic blood pressure were included. Results: Intraoperative HDI was significantly higher in the LRA group than in the LLA (27% vs. 9.4%, p &lt; 0.001). In the multivariate regression analysis, right-sided tumours showed a higher risk of intraoperative HDI (odds ratio [OR] 5.625, 95% confidence interval [CI], 1.147–27.577, p = 0.033). The tumor size (OR 11.019, 95% CI 3.996–30.38, p &lt; 0.001), presence of preoperative comorbidities [diabetes mellitus, hypertension, and coronary heart disease] (OR 7.918, 95% CI 1.323–47.412, p = 0.023), and preoperative systolic blood pressure (OR 1.265, 95% CI 1.07–1.495, p = 0.006) were associated with a higher risk of HDI in both LRA and LLA, with no superiority of one side over the other. Conclusion: LRA was associated with a significantly higher intraoperative HDI than LLA. Right-sided PHEO was a risk factor for intraoperative HDI