7 research outputs found
Meloxicam encapsulated nanostructured colloidal self‐assembly for evaluating antitumor and anti‐inflammatory efficacy in 3D printed scaffolds
Preparation and optimization of tablets containing a self-nano-emulsifying drug delivery system loaded with rosuvastatin
Biotransformation of Meloxicam by Cunninghamella blakesleeana: Significance of Carbon and Nitrogen Source
Formulation and In Vitro and In Vivo Evaluation of Lipid-Based Terbutaline Sulphate Bi-layer Tablets for Once-Daily Administration
Development of Tizanidine HCl-Meloxicam loaded mucoadhesive buccal films: In-vitro and in-vivo evaluation
Cyclodextrins for Essential Oils Applications
International audiencehere is a growing interest for the aromatic and biological properties of essential oils, as alternatives to synthetic chemicals. Nonetheless, essential oils and their components are poorly soluble in water, and are highly sensitive to degradation and evaporation. Encapsulation in cyclodextrins can reduce these drawbacks and improve the properties of essential oils. Cyclodextrins are non-toxic cyclic oligosaccharides obtained by enzymatic degradation of starch. Cyclodextrins inclusion complexes find applications in the food, pharmaceutical and cosmetic industries.This chapter reviews encapsulation of essential oils in cyclodextrins. The strength of binding between cyclodextrins and essential oils components covers a wide range of formation constants with values ranging from 13 to 166,338 M−1. The encapsulation in cyclodextrins increases the aqueous solubility of essential oils up to 16-fold and reduces oil photodegradation rates up to 44-fold, while ensuring gradual release of oils. This chapter also discusses the effect of encapsulation on biological activities such as antimicrobial and antioxidant properties of essential oils. Biological effects depend on the nature and concentrations of essential oils and cyclodextrin, the tested microorganism, and other factors. Emerging cyclodextrin-based approaches for textiles and nanofibers are also discussed
