Evaluation of the Problem Behavior Frequency Scale-teacher Report Form for Assessing Behavior in a Sample of Urban Adolescents

© 2018 American Psychological Association. This study evaluated the structure and validity of the Problem Behavior Frequency Scale-Teacher Report Form (PBFS-TR) for assessing students\u27 frequency of specific forms of aggression and victimization, and positive behavior. Analyses were conducted on two waves of data from 727 students from two urban middle schools (Sample 1) who were rated by their teachers on the PBFS-TR and the Social Skills Improvement System (SSIS), and on data collected from 1,740 students from three urban middle schools (Sample 2) for whom data on both the teacher and student report version of the PBFS were obtained. Confirmatory factor analyses supported first-order factors representing 3 forms of aggression (physical, verbal, and relational), 3 forms of victimization (physical, verbal and relational), and 2 forms of positive behavior (prosocial behavior and effective nonviolent behavior), and higher-order factors representing aggression, victimization, and positive behavior. Strong measurement invariance was established over gender, grade, intervention condition, and time. Support for convergent validity was found based on correlations between corresponding scales on the PBFS-TR and teacher ratings on the SSIS in Sample 1. Significant correlations were also found between teacher ratings on the PBFS-TR and student ratings of their behavior on the Problem Behavior Frequency Scale-Adolescent Report (PBFS-AR) and a measure of nonviolent behavioral intentions in Sample 2. Overall the findings provided support for the PBFS-TR and suggested that teachers can provide useful data on students\u27 aggressive and prosocial behavior and victimization experiences within the school setting

Emergency Wildlife Management Response to Protect Evidence Associated with the Terrorist Attack on the World Trade Center, New York City

At the request of the New York City Police Department, the PoIt Authority of New York and New Jersey, and the New York State Department of Environmental Conservation, a team of USDA APHIS Wildlife Services (WS) biologists mobilized in less than 24 hours to assist federal, state and local law enforcement officials in managing birds and rodents impacting the recovey of evidence as a result of the September 11, 2001 terrorist attacks on the World Trade Center. During the 10-month recovery effort fiom September 2001 to June 2002, more than 1.7 million tons of debris was shipped fiom Ground Zero in Manhatran to a high-security crime scene at the Fresh W s Landfill (FKL), Staten Island, New York Close to a billion pieces of debris were sorted by law enforcement officials to recover personal effects, human remains, and other evidence to document the crime and identlfy victims, as part of the largest forensic investigation in U.S. history. Within days of bringing debris to FKL, more than 2,600 gulls were on site, disrupting work of law enforcement officials and creating a concem that evidence would be lost to birds. Historically, FKL has been a feeding and loafmg site for over 100,000 gulls. To address this unprecedented wildlife damage management problem, WS implemented an integrated bud and rodent management program that involved 69 biologists from 23 states. The goal was to reduce the impact of pus, crows, house mice, and Norway rats on law enforcement personnel, equipment, and evidence collection including a zero-tolerance policy for gulls and crows landing on the working face. A combination of population surveys and direct management activities targeting gulls and crows was initiated 12-14 hours a day, 7 days a week using visual and noise deterrents including pyrotechnics, mylar tape, human and dead-bud effigies, lasers, paint ball guns, and lethal removal of a limited number of birds. In addition, commensal rodent surveys with snap traps were conducted twice monthly to document population trends and explore the need for rodent control on site. We deployed over 23,000 pyrotechnics and dispased over 172,000 gulls and 5,000 crows fiom the site. We removed 293 house mice and 46 Norway rats in 6,000 trapnights. \u27Ibe program was highly effective in preventing gulls and crows from feeding on remains and disrupting workers. We discuss other key lessons learned regarding an emergency response program to manage wildlife

Emergency Wildlife Management Response to Protect Evidence Associated with the Terrorist Attack on the World Trade Center, New York City

At the request of the New York City Police Department, the PoIt Authority of New York and New Jersey, and the New York State Department of Environmental Conservation, a team of USDA APHIS Wildlife Services (WS) biologists mobilized in less than 24 hours to assist federal, state and local law enforcement officials in managing birds and rodents impacting the recovey of evidence as a result of the September 11, 2001 terrorist attacks on the World Trade Center. During the 10-month recovery effort fiom September 2001 to June 2002, more than 1.7 million tons of debris was shipped fiom Ground Zero in Manhatran to a high-security crime scene at the Fresh W s Landfill (FKL), Staten Island, New York Close to a billion pieces of debris were sorted by law enforcement officials to recover personal effects, human remains, and other evidence to document the crime and identlfy victims, as part of the largest forensic investigation in U.S. history. Within days of bringing debris to FKL, more than 2,600 gulls were on site, disrupting work of law enforcement officials and creating a concem that evidence would be lost to birds. Historically, FKL has been a feeding and loafmg site for over 100,000 gulls. To address this unprecedented wildlife damage management problem, WS implemented an integrated bud and rodent management program that involved 69 biologists from 23 states. The goal was to reduce the impact of pus, crows, house mice, and Norway rats on law enforcement personnel, equipment, and evidence collection including a zero-tolerance policy for gulls and crows landing on the working face. A combination of population surveys and direct management activities targeting gulls and crows was initiated 12-14 hours a day, 7 days a week using visual and noise deterrents including pyrotechnics, mylar tape, human and dead-bud effigies, lasers, paint ball guns, and lethal removal of a limited number of birds. In addition, commensal rodent surveys with snap traps were conducted twice monthly to document population trends and explore the need for rodent control on site. We deployed over 23,000 pyrotechnics and dispased over 172,000 gulls and 5,000 crows fiom the site. We removed 293 house mice and 46 Norway rats in 6,000 trapnights. \u27Ibe program was highly effective in preventing gulls and crows from feeding on remains and disrupting workers. We discuss other key lessons learned regarding an emergency response program to manage wildlife

Emergency Wildlife Management Response to Protect Evidence Associated with the Terrorist Attack on the World Trade Center, New York City

At the request of the New York City Police Department, the PoIt Authority of New York and New Jersey, and the New York State Department of Environmental Conservation, a team of USDA APHIS Wildlife Services (WS) biologists mobilized in less than 24 hours to assist federal, state and local law enforcement officials in managing birds and rodents impacting the recovey of evidence as a result of the September 11, 2001 terrorist attacks on the World Trade Center. During the 10-month recovery effort fiom September 2001 to June 2002, more than 1.7 million tons of debris was shipped fiom Ground Zero in Manhatran to a high-security crime scene at the Fresh W s Landfill (FKL), Staten Island, New York Close to a billion pieces of debris were sorted by law enforcement officials to recover personal effects, human remains, and other evidence to document the crime and identlfy victims, as part of the largest forensic investigation in U.S. history. Within days of bringing debris to FKL, more than 2,600 gulls were on site, disrupting work of law enforcement officials and creating a concem that evidence would be lost to birds. Historically, FKL has been a feeding and loafmg site for over 100,000 gulls. To address this unprecedented wildlife damage management problem, WS implemented an integrated bud and rodent management program that involved 69 biologists from 23 states. The goal was to reduce the impact of pus, crows, house mice, and Norway rats on law enforcement personnel, equipment, and evidence collection including a zero-tolerance policy for gulls and crows landing on the working face. A combination of population surveys and direct management activities targeting gulls and crows was initiated 12-14 hours a day, 7 days a week using visual and noise deterrents including pyrotechnics, mylar tape, human and dead-bud effigies, lasers, paint ball guns, and lethal removal of a limited number of birds. In addition, commensal rodent surveys with snap traps were conducted twice monthly to document population trends and explore the need for rodent control on site. We deployed over 23,000 pyrotechnics and dispased over 172,000 gulls and 5,000 crows fiom the site. We removed 293 house mice and 46 Norway rats in 6,000 trapnights. \u27Ibe program was highly effective in preventing gulls and crows from feeding on remains and disrupting workers. We discuss other key lessons learned regarding an emergency response program to manage wildlife

Widespread closure of HIV prevention and care services places youth at higher risk during the COVID-19 pandemic

BACKGROUND: Central to measuring the impact of the COVID-19 pandemic on HIV is understanding the role of loss of access to essential HIV prevention and care services created by clinic and community-based organization closures. In this paper, we use a comprehensive list of HIV prevention services in four corridors of the US heavily impacted by HIV, developed as part of a large RCT, to illustrate the potential impact of service closure on LGBTQ+ youth. METHODS: We identified and mapped LGBTQ+ friendly services offering at least one of the following HIV-related services: HIV testing; STI testing; PrEP/PEP; HIV treatment and care; and other HIV-related services in 109 counties across four major interstate corridors heavily affected by HIV US Census regions: Pacific (San Francisco, CA to San Diego, CA); South-Atlantic (Washington, DC to Atlanta, GA); East-North-Central (Chicago, IL to Detroit, MI); and East-South-Central (Memphis, TN to New Orleans, LA). RESULTS: There were a total of 831 LGBTQ+ youth-friendly HIV service providers across the 109 counties. There was a range of LGBTQ+ youth-friendly HIV-service provider availability across counties (range: 0-14.33 per 10,000 youth aged 13-24 (IQR: 2.13), median: 1.09); 9 (8.26%) analyzed counties did not have any LGBTQ+ youth-friendly HIV service providers. The Pearson correlation coefficient for the correlation between county HIV prevalence and LGBTQ+ youth-friendly HIV service provider density was 0.16 (p = 0.09), suggesting only a small, non-statistically significant linear relationship between a county's available LGBTQ+ youth-friendly HIV service providers and their HIV burden. CONCLUSIONS: As the COVID-19 pandemic continues, we must find novel, affordable ways to continue to provide sexual health, mental health and other support services to LGBTQ+ youth

The global burden of injury: Incidence, mortality, disability-adjusted life years and time trends from the global burden of disease study 2013

Background The Global Burden of Diseases (GBD), Injuries, and Risk Factors study used the disabilityadjusted life year (DALY) to quantify the burden of diseases, injuries, and risk factors. This paper provides an overview of injury estimates from the 2013 update of GBD, with detailed information on incidence, mortality, DALYs and rates of change from 1990 to 2013 for 26 causes of injury, globally, by region and by country. Methods Injury mortality was estimated using the extensive GBD mortality database, corrections for illdefined cause of death and the cause of death ensemble modelling tool. Morbidity estimation was based on inpatient and outpatient data sets, 26 cause-of-injury and 47 nature-of-injury categories, and seven follow-up studies with patient-reported long-term outcome measures. Results In 2013, 973 million (uncertainty interval (UI) 942 to 993) people sustained injuries that warranted some type of healthcare and 4.8 million (UI 4.5 to 5.1) people died from injuries. Between 1990 and 2013 the global age-standardised injury DALY rate decreased by 31% (UI 26% to 35%). The rate of decline in DALY rates was significant for 22 cause-of-injury categories, including all the major injuries. Conclusions Injuries continue to be an important cause of morbidity and mortality in the developed and developing world. The decline in rates for almost all injuries is so prominent that it warrants a general statement that the world is becoming a safer place to live in. However, the patterns vary widely by cause, age, sex, region and time and there are still large improvements that need to be made

Constructing a web‐based health directory for adolescent men who have sex with men: Strategies for development and resource verification

Online health directories are increasingly used to locate health services and community resources, providing contact and service information that assists users in identifying resources that may meet their health and wellness needs. However, service locations require additional vetting when directories plan to refer vulnerable populations. As a tool included as part of a trial of a mobile life skills intervention for cisgender adolescent men who have sex with men (AMSM; ages 13-18), we constructed and verified resources for an online resource directory focused on linking young people to LGBTQ+ friendly and affirming local health and community social services resources. We collected information for 2301 individual directory listings through database and internet searches. To ensure the listings aligned with the project's focus of supporting young sexual minority men, we developed multiple data verification assessments to ensure community appropriateness resulting in verification of 1833 resources suitable for inclusion in our locator tool at project launch (March 2018). We offer lessons learned and future directions for researchers and practitioners who may benefit from adapting our processes and strategies for building culturally-tailored resource directories for vulnerable populations

The Global Leadership Initiative on Malnutrition (GLIM) inflammation criteria to predict survival in patients with advanced cancer:A prospective cohort study

Background: The Global Leadership Initiative on Malnutrition (GLIM) criteria provides a framework forassessing cachexia in cancer patients. However, the role of systemic inflammation in this frameworkneeds further exploration.Methods: This study analyzed a cohort of 388 advanced cancer patients from 18 oncological care settings.C-reactive protein (CRP), the modified Glasgow Prognostic Score (mGPS) and Neutrophil-to-LymphocyteRatio (NLR) were used to assess systemic inflammation. Associations between these inflammatorymarkers and Weight Loss (WL), Body Mass Index (BMI), Skeletal Muscle Index (SMI), and survival outcomes (OS) were evaluated using Chi-square and KaplaneMeier survival analyses.Results: CRP was significantly associated with ECOG-PS (p < 0.01), and WL (p < 0.05). mGPS wassignificantly associated with ECOG-PS (p < 0.001), WL (p < 0.001), and BMI (p < 0.05). NLR wassignificantly associated with ECOG-PS (p < 0.05), WL (p < 0.001), and BMI (p < 0.05). CRP (p < 0.001),mGPS (p < 0.001), NLR (p < 0.001), WL (p < 0.001), and SMI (p < 0.05) were significantly associated withOS, but not BMI (p ¼ 0.23). Combining CRP, mGPS, NLR, with WL, BMI, and SMI significantly improved OSprediction. WL was significantly associated with OS in patients with NLR<3 (p < 0.05) but not inCRP10 mg/L or mGPS ¼ 0. SMI was significantly associated with OS in patients with mGPS ¼ 0(p < 0.05).Conclusion: Systemic inflammation, as assessed by CRP, mGPS and NLR, significantly improves therelationship between phenotypic criteria and OS. These findings support the GLIM framework's inclusionof systemic inflammation as a critical factor. Given its strong predictive value, systemic inflammationshould be prioritized in routine clinical assessments of cancer patients, with mGPS having greaterprognostic value within the GLIM framewor

Characterization of a novel polyextremotolerant fungus, \u3ci\u3eExophiala viscosa\u3c/i\u3e, with insights into its melanin regulation and ecological niche

Black yeasts are polyextremotolerant fungi that contain high amounts of melanin in their cell wall and maintain a primar yeast form. These fungi grow in xeric, nutrient depletes environments which implies that they require highly flexible metabolisms and have been suggested to contain the ability to form lichen-like mutualisms with nearby algae and bacteria. However, the exact ecological niche and interactions between these fungi and their surrounding community are not well understood. We have isolated 2 novel black yeasts from the genus Exophiala that were recovered from dryland biological soil crusts. Despite notable differences in colony and cellular morphology, both fungi appear to be members of the same species, which has been named Exophiala viscosa (i.e. E. viscosa JF 03-3 Goopy and E. viscosa JF 03-4F Slimy). A combination of whole genome sequencing, phenotypic experiments, and melanin regulation experiments have been performed on these isolates to fully characterize these fungi and help decipher their fundamental niche within the biological soil crust consortium. Our results reveal that E. viscosa is capable of utilizing a wide variety of carbon and nitrogen sources potentially derived from symbiotic microbes, can withstand many forms of abiotic stresses, and excretes melanin which can potentially provide ultraviolet resistance to the biological soil crust community. Besides the identification of a novel species within the genus Exophiala, our study also provides new insight into the regulation of melanin production in polyextremotolerant fungi

Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy

© The Author 2017. Duchenne muscular dystrophy (DMD) is a neuromuscular disease that predominantly affects boys as a result of mutation(s) in the dystrophin gene. DMD is characterized by musculoskeletal and cardiopulmonary complications, resulting in shorter life-span. Boys afflicted by DMD typically exhibit symptoms within 3-5 years of age and declining physical functions before attaining puberty. We hypothesized that rapidly deteriorating health of pre-pubertal boys with DMD could be due to diminished anabolic actions of androgens in muscle, and that intervention with an androgen receptor (AR) agonist will reverse musculoskeletal complications and extend survival. While castration of dystrophin and utrophin double mutant (mdx-dm) mice to mimic pre-pubertal nadir androgen condition resulted in premature death, maintenance of androgen levels extended the survival. Non-steroidal selective-AR modulator, GTx-026, which selectively builds muscle and bone was tested in X-linked muscular dystrophy mice (mdx). GTx-026 significantly increased body weight, lean mass and grip strength by 60-80% over vehicle-treated mdx mice. While vehicle-treated castrated mdx mice exhibited cardiopulmonary impairment and fibrosis of heart and lungs, GTx-026 returned cardiopulmonary function and intensity of fibrosis to healthy control levels. GTx-026 elicits its musculoskeletal effects through pathways that are distinct from dystrophin-regulated pathways, making AR agonists ideal candidates for combination approaches. While castration of mdx-dm mice resulted in weaker muscle and shorter survival, GTx-026 treatment increased the muscle mass, function and survival, indicating that androgens are important for extended survival. These preclinical results support the importance of androgens and the need for intervention with AR agonists to treat DMD-affected boys