Some operators that preserve the locality of a pseudovariety of semigroups

It is shown that if V is a local monoidal pseudovariety of semigroups, then K(m)V, D(m)V and LI(m)V are local. Other operators of the form Z(m)(_) are considered. In the process, results about the interplay between operators Z(m)(_) and (_)*D_k are obtained.Comment: To appear in International Journal of Algebra and Computatio

Locais de venda de medicamentos não sujeitos a receita médica: caracterização da população utente e do nível de satisfação com o atendimento

A possibilidade de venda de medicamentos não sujeitos a receita médica fora das farmácias provocou uma enorme revolução no sector. Esta medida visou, entre outros aspectos, a redução dos preços destes medicamentos e a melhoria da acessibilidade do consumidor a estes produtos, pelo aumento do número de postos de venda. No entanto, com a excepção do efeito sobre o preço dos medicamentos que esta medida teve, pouco se conhece sobre a qualidade dos serviços prestados nos locais de venda e a percepção sobre essa qualidade. Objectivo do estudo: caracterizar a população-utente de locais de venda de MNSRM e determinar o seu grau de satisfação com a organização e o atendimento prestado no local

Development of a Novel Nanotextured Titanium Implant. An Experimental Study in Rats.

This animal study evaluated the osseointegration level of a new nanotextured titanium surface produced by anodization. Ti-cp micro-implants (1.5 mm diameter by 2.5 mm in length) divided into two groups: titanium nanotextured surface treatment (Test Group) and acid etched surface treatment (Control Group). Surface characterization included morphology analysis using scanning electron microscopy and wettability by measuring contact angle. Sixteen Wistar rats were submitted to two micro implants surgical placement procedures. In each rat, one type of micro implant placed in each tibia. The animals sacrificed after two (T1) and six weeks (T2) post-implantation. After the euthanasia, tibias processed for histomorphometric analysis, which allowed the evaluation of bone to implant contact (BIC) and the bone area fraction occupancy between the threads (BAFO). Our surface analysis data showed that the Control Group exhibited an irregular and non-homogenous topography while the Test Group showed a nanotextured surface. The Test Group showed higher wettability (contact angle = 5.1 ± 0.7°) than the Control Group (contact angle = 75.5 ± 4.6°). Concerning the histomorphometric analysis results for T1, Control and Test groups showed BIC percentages of 41.3 ± 15.2% and 63.1 ± 8.7% (p < 0.05), respectively, and for BAFO, 28.7 ± 13.7% and 54.8 ± 7.5%, respectively (p < 0.05). For T2, the histomorphometric analysis for Control and Test groups showed BIC percentages of 51.2 ± 11.4% and 64.8 ± 7.4% (p < 0.05), respectively and for BAFO, 36.4 ± 10.3% and 57.9 ± 9.3% (p < 0.05), respectively. The findings of the current study confirmed that the novel nanotextured surface exhibited superior wettability, improved peri-implant bone formation, and expedited osseointegration

A Monte Carlo study of the fluctuations in Xe electroluminescence yield: pure Xe vs Xe doped with CH4 or CF4 and planar vs cylindrical geometries

Monte Carlo simulation is used to investigate the fluctuations in the Xe proportional electroluminescence (EL) yield H (also known as secondary scintillation) produced by sub-ionization primary electrons drifting in the gas under appropriate electric fields, comparing pure Xe gas with Xe doped with CH4 or CF4. The work is modeled on gas detectors of the gas proportional-scintillation type, where amplification is achieved through the production of EL under a charge-multiplication free regime. The addition of the molecular gases to Xe reduces electron diffusion, a desirable effect in large size detectors where primary electrons drift across a long absorption/drift region. However, the presence of the molecules reduces H and increases its fluctuations. In the case of CF4, the effects are very strong due to significant electron attachment in the EL field range, ruling out CF4 as an acceptable additive. The addition of CH4 affects H and its fluctuations to a much lower extent, and CH4 concentrations lower than ~1% may be an appropriate choice. In addition, Monte Carlo calculations in pure Xe under cylindrical geometry in a regime below charge multiplication have shown that fluctuations in the EL yield H are an order of magnitude higher than for planar geometry. For both geometries, though, the fluctuations have a negligible effect on the energy resolution, and variations of the anode radius in cylindrical geometry or grid parallelism in planar geometry may be a more significant cause of concern.Comment: 24 pages,11 figures; 2 typos have been corrected on Fig.4 captio

A UV Sensitive Integrated Micromegas with Timepix Readout

This article presents a detector system consisting of three components, a CMOS imaging array, a gaseous-detector structure with a Micromegas layout and a UV-photon sensitive CsI reflective photocathode. All three elements have been monolithically integrated using simple post-processing steps. The Micromegas structure and the CMOS imaging chip are not impacted by the CsI deposition. The detector operated reliably in He/isobutane mixtures and attained charge gains with single photons up to a level of 6 \cdot 10^4. The Timepix CMOS array permitted high resolution imaging of single UV-photons. The system has an MTF50 of 0.4 lp/pixel which corresponds to app. 7 lp/mm.Comment: 4 pages with 8 figures. Submitted to Nucl. Instr. and Meth. A (Elsevier) for proceedings of VCI 2010

Efficient ion blocking in gaseous detectors and its application to gas-avalanche photomultipliers sensitive in the visible-light range

A novel concept for ion blocking in gas-avalanche detectors was developed, comprising cascaded micro-hole electron multipliers with patterned electrodes for ion defocusing. This leads to ion blocking at the 10^{-4} level, in DC mode, in operation conditions adequate for TPCs and for gaseous photomultipliers. The concept was validated in a cascaded visible-sensitive gas avalanche photomultiplier operating at atmospheric pressure of Ar/CH_{4} (95/5) with a bi-alkali photocathode. While in previous works high gain, in excess of 10^{5}, was reached only in a pulse-gated cascaded-GEM gaseous photomultiplier, the present device yielded, for the first time, similar gain in DC mode. We describe shortly the physical processes involved in the charge transport within gaseous photomultipliers and the ion blocking method. We present results of ion backflow fraction and of electron multiplication in cascaded patterned-electrode gaseous photomultiplier with K-Cs-Sb, Na-K-Sb and Cs-Sb visible-sensitive photocathodes, operated in DC mode.Comment: Proceeding paper to 10-th International Conference On Instrumentation For Colliding Beam Physics, Budker Institute of Nuclear Physics, Novosibirsk, Russia, February 28 - March 5, 2008, Submitted to NIMA, 5 pages, 7 figure

Development of high-gain gaseous photomultipliers for the visible spectral range

We summarize the development of visible-sensitive gaseous photomultipliers, combining a semitransparent bi-alkali photocathode with a state-of-the-art cascaded electron multiplier. The latter has high photoelectron collection efficiency and a record ion blocking capability. We describe in details the system and methods of photocathode production and characterization, their coupling with the electron multiplier and the gaseous-photomultiplier operation and characterization in a continuous mode. We present results on the properties of laboratory-produced K$_2$CsSb, Cs$_3$Sb and Na$_2$KSb photocathodes and report on their stability and QE in gas; K$_2$CsSb photocathodes yielded QE values in Ar/CH$_4$(95/5) above 30% at wavelengths of 360-400 nm. The novel gaseous photomultiplier yielded stable operation at gains of 10$^5$, in continuous operation mode, in 700 Torr of this gas; its sensitivity to single photons was demonstrated. Other properties are described. The successful detection of visible light with this gas-photomultiplier pave ways towards further development of large-area sealed imaging detectors, of flat geometry, insensitive to magnetic fields, which might have significant impact on light detection in numerous fields.Comment: 22 pages, 12 figures, for submission to JINS

MPGDs in Compton imaging with liquid-xenon

The interaction of radiation with liquid xenon, inducing both scintillation and ionization signals, is of particular interest for Compton-sequences reconstruction. We report on the development and recent results of a liquid-xenon time-projection chamber, dedicated to a novel nuclear imaging technique named "3 gamma imaging". In a first prototype, the scintillation is detected by a vacuum photomultiplier tube and the charges are collected with a MICROMEGAS structure; both are fully immersed in liquid xenon. In view of the final large-area detector, and with the aim of minimizing dead-zones, we are investigating a gaseous photomultiplier for recording the UV scintillation photons. The prototype concept is presented as well as preliminary results in liquid xenon. We also present soft x-rays test results of a gaseous photomultiplier prototype made of a double Thick Gaseous Electron Multiplier (THGEM) at normal temperature and pressure conditions.Comment: presented at MPGD09, CRETE, June 2009; to be published in JINST Proceedings, PDF, 10 pages, 11 figure