Androgenic Effect and Phytochimie of the Bark of Trunk of Buchholzia coriacea Engl. (Capparidaceae)

The testosterone is the main androgen produced by the testes among the males.  Her absence is responsible for erectile dysfunction and the loss of the sexual performance. The aim of the present study is to evaluate the androgenic effect and to determine the profile phytochemestry of the barks of trunk of B. coriacea. Fifteen days after the castration, the animals left in group and, received the aqueous extract of B. coriacea (100, 250 and 500 mg/kg, p.o). The sexual parameters (mounts sexual, number of erections, number of ejaculations and the time of latency) have been valued, and compared, to the witnesses groups: water distilled (0,5 ml/100 mg, p.o) and Enanthate of testosterone (1 mg/mL, i.m). The dosage of the testosterone has been achieved by the technic of ELYSA analysis. The determination of the chemical families has been achieved by the technique of coloration in tubes. The aqueous extract of B. coriacea (100,250 and 500 mg/kg, p.o) has an effect androgenic because managed daily during 15 days, it provokes an increase of the rate plasmatic of the testosterone and the bodily weight of the rats, maintains the sexual parameters among the castrated rat, extract the number of ejaculations. The barks of trunk of B. coriacea would contain the stérols, the flavonoides, the saponosids that could be responsible for the sexual effects and androgénic observed. The aqueous extract of the plant would possess the properties androgenic would be to advise the patients presenting problems of masculine barrenness.  Keywords:  Androgen - Phytochimie - Buchholzia - coriacea&nbsp

Iodine-125 brachytherapy for brain tumours - a review

Iodine-125 brachytherapy has been applied to brain tumours since 1979. Even though the physical and biological characteristics make these implants particularly attractive for minimal invasive treatment, the place for stereotactic brachytherapy is still poorly defined

CARDIOVASCULAR POTENTIAL OF THE BARKS OF TRUNK OF BUCHHOLZIA CORIACEA (CAPPARIDACEAE) AT THE ALBINO MALE RAT

Buchholzia coriacea is a plant of the Congolese pharmacopeia. Her barks of trunk were the subject of aphrodisiac study in our laboratory. But her effect on the arterial pressure, the cardiac frequency and on the contractions of the heart, remain even unknown. This is how the present work aims the assessment of the cardiovascular potential of the barks of trunk of this plant at the albino male rat. The effects on the mean arterial pressure and the cardiac frequency at the rat normotended have been valued by the method invasive whereas the classic model of drip of isolated heart of batrachian has been used to value the effects on the heart isolated of toad. The administration of the aqueous extract of the barks of trunk of B. coriacea (10, 20 and 40 mg/kg, i.v) decreases the mean arterial pressure and the cardiac frequency as the yohimbine(1mg/kg, i.v) and the µg acetylcholine (50 µg / Kg, i.v).This effects hypotensor and negative chronotrope are raised completely by the atropine (1 mg / kg. i.v), ce that conrms the implication of the receiving muscarinics in the mechanism of action of this extract. To the concentrations of 2; 2,5 and 3 mg / ml extracts it aqueous of the barks of trunk of B. coriacea decreases strength and the frequency of the contractions of the heart isolated of toad and to 4 and 5 mg/ml, it drags to a reversible stop of the contractions of the heart isolated of toad.</jats:p

Androgenic Effect and Phytochimie of the Bark of Trunk of Buchholzia coriacea Engl. (Capparidaceae)

The testosterone is the main androgen produced by the testes among the males.  Her absence is responsible for erectile dysfunction and the loss of the sexual performance. The aim of the present study is to evaluate the androgenic effect and to determine the profile phytochemestry of the barks of trunk of B. coriacea. Fifteen days after the castration, the animals left in group and, received the aqueous extract of B. coriacea (100, 250 and 500 mg/kg, p.o). The sexual parameters (mounts sexual, number of erections, number of ejaculations and the time of latency) have been valued, and compared, to the witnesses groups: water distilled (0,5 ml/100 mg, p.o) and Enanthate of testosterone (1 mg/mL, i.m). The dosage of the testosterone has been achieved by the technic of ELYSA analysis. The determination of the chemical families has been achieved by the technique of coloration in tubes. The aqueous extract of B. coriacea (100,250 and 500 mg/kg, p.o) has an effect androgenic because managed daily during 15 days, it provokes an increase of the rate plasmatic of the testosterone and the bodily weight of the rats, maintains the sexual parameters among the castrated rat, extract the number of ejaculations. The barks of trunk of B. coriacea would contain the stérols, the flavonoides, the saponosids that could be responsible for the sexual effects and androgénic observed. The aqueous extract of the plant would possess the properties androgenic would be to advise the patients presenting problems of masculine barrenness. &#x0D; Keywords:  Androgen - Phytochimie - Buchholzia - coriacea </jats:p