A great friggin' swindle? Sex Pistols, school kids and 1979

This article examines the popularity of the Sex Pistols’ song “Friggin’ in the Riggin’” and its parent album The Great Rock ‘n’ Roll Swindle. It argues that in 1979 the Sex Pistols attracted a new and younger audience, one that has been neglected in previous studies of the band, which tend instead to focus on the years 1976 and 1977 and the band’s original coterie of followers. This article locates the teenage appeal of “Friggin’ in the Riggin’” in its themes of swearing, sex and piracy. It also explores the media infrastructure that enabled young adolescents to access this music. Following on from this, the article charts the triumph of Johnny Rotten’s Sex Pistols’ narrative over that of Malcolm McLaren. The Great Rock ‘n’ Roll Swindle fell prey to notions of authenticity, coherence and the canonical tastes of young adults

The ACPGBI AI taskforce report: A mixed‐methods roadmap for AI in colorectal surgery

© 2025 The Author(s). Colorectal Disease published by John Wiley & Sons Ltd on behalf of Association of Coloproctology of Great Britain and Ireland.Aim: The ACPGBI has commissioned a taskforce to devise a strategy for integrating artificial intelligence (AI) into colorectal surgery. This report aims to (i) map current AI adoption amongst UK colorectal surgeons; (ii) evaluate knowledge, attitudes, perceptions and experience of AI technologies; and (iii) establish priority recommendations to drive innovation across the specialty. Methods: A prospective 45‐item questionnaire was circulated to the ACPGBI membership. Questionnaire findings were explored at a multidisciplinary round table of surgeons, allied professionals, computer scientists and lawyers. Strategic recommendations were then generated. Results: 122 members responded (75.4% consultants; 72.1% male; modal age 41–50 years). Although 43.5% used AI daily, only one third said they could explain key concepts within AI. 86.9% anticipated routine future‐AI use, with documentation and imaging ranked highest. 88.5% endorsed formal AI training. Major obstacles were unclear regulation, cost, medicolegal liability and professional or patient distrust. The round table generated 17 recommendations across clinical, educational and research domains and a ten‐point action plan, including the establishment of a Colorectal AI Committee and the creation of an open‐source colorectal foundational data initiative. Conclusion: This taskforce report combines questionnaire insights from the ACPGBI membership and expert debate into 17 key recommendations and a ten‐point action plan that will set the direction of future colorectal AI practice. The objective is to establish a framework through which colorectal surgical practice can be augmented by safe, trustworthy AI.Unfunde

Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic

Over 30 years ago Professor David Barker first proposed the theory that events in early life could explain an individual\u27s risk of non-communicable disease in later life: the developmental origins of health and disease (DOHaD) hypothesis. During the 1990s the validity of the DOHaD hypothesis was extensively tested in a number of human populations and the mechanisms underpinning it characterised in a range of experimental animal models. Over the past decade, researchers have sought to use this mechanistic understanding of DOHaD to develop therapeutic interventions during pregnancy and early life to improve adult health. A variety of animal models have been used to develop and evaluate interventions, each with strengths and limitations. It is becoming apparent that effective translational research requires that the animal paradigm selected mirrors the tempo of human fetal growth and development as closely as possible so that the effect of a perinatal insult and/or therapeutic intervention can be fully assessed. The guinea pig is one such animal model that over the past two decades has demonstrated itself to be a very useful platform for these important reproductive studies. This review highlights similarities in the in utero development between humans and guinea pigs, the strengths and limitations of the guinea pig as an experimental model of DOHaD and the guinea pig\u27s potential to enhance clinical therapeutic innovation to improve human health. (Figure presented.)

Who are the end-use(r)s of smart cities?: A synthesis of conversations in Amsterdam

Today, withdrawing from digital space would mean giving up on countless pleasures and conveniences afforded by communication and navigation devices. Even if one wanted to withdraw, living offline has become rather difficult. Around the world urban life has become digitized and datafied to a degree that any attempt at living even for a few days without engagement with digital space would likely require a withdrawal from urban life altogether: from travel, work, and personal relations as we nowadays experience and live them. Many urbanites produce digital data through almost everything they do. We get up in the morning and use a mobile phone that is constantly emitting information to check our email, the news, and social media. We travel to work using an electronic travel card or in a car with various GPS and digital systems. We walk down streets where signals from our phones and other devices are captured and read by wifi beacons and MAC address sensors, and our images by CCTV. We use apps that emit details of our location, we tweet, we tag, we check in. We make phone calls through particular antennas set up by our mobile phone providers. We interact with the city digitally by paying our taxes, living in our houses, using city services, and offering feedback to the authorities. All day, digital signatures are embedded in the technologies we use, emitted as we communicate and move around, and signaled by most of our activities. The picture that builds up about us in the course of every day is both behavioral and spatial in ways that are often opaque to us. Actual and possible effects of digitalization and datafication of urban life are critically debated in scholarly and policy circles; and Liesbet Van Zoonen (2015) has observed that city governments today are faced with a super-wicked problem of data governance (Levin et al. 2012). In this context citizens are both contributors to the digitalization and datafication, as well as being affected by these processes