489 research outputs found

    Some New Selected Recipes: Tested and Proved Good

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    A booklet of recipes provided by the Baker Extract Company of Springfield, Massachusetts and Portland, Maine, circa 1920. Baker Extract Company is one of several extract manufacturers listed in Portland city directories from 1891 to 1925

    Enoxaparin versus unfractionated heparin with fibrinolysis for ST-elevation myocardial infarction

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    Background: Unfractionated heparin is often used as adjunctive therapy with fibrinolysis in patients with ST-elevation myocardial infarction. We compared a low-molecular-weight heparin, enoxaparin, with unfractionated heparin for this purpose. Methods: We randomly assigned 20,506 patients with ST-elevation myocardial infarction who were scheduled to undergo fibrinolysis to receive enoxaparin throughout the index hospitalization or weight-based unfractionated heparin for at least 48 hours. The primary efficacy end point was death or nonfatal recurrent myocardial infarction through 30 days. Results: The primary end point occurred in 12.0 percent of patients in the unfractionated heparin group and 9.9 percent of those in the enoxaparin group (17 percent reduction in relative risk, P<0.001). Nonfatal reinfarction occurred in 4.5 percent of the patients receiving unfractionated heparin and 3.0 percent of those receiving enoxaparin (33 percent reduction in relative risk, P<0.001); 7.5 percent of patients given unfractionated heparin died, as did 6.9 percent of those given enoxaparin (P=0.11). The composite of death, nonfatal reinfarction, or urgent revascularization occurred in 14.5 percent of patients given unfractionated heparin and 11.7 percent of those given enoxaparin (P<0.001); major bleeding occurred in 1.4 percent and 2.1 percent, respectively (P<0.001). The composite of death, nonfatal reinfarction, or nonfatal intracranial hemorrhage (a measure of net clinical benefit) occurred in 12.2 percent of patients given unfractionated heparin and 10.1 percent of those given enoxaparin (P<0.001). Conclusions: In patients receiving fibrinolysis for ST-elevation myocardial infarction, treatment with enoxaparin throughout the index hospitalization is superior to treatment with unfractionated heparin for 48 hours but is associated with an increase in major bleeding episodes. These findings should be interpreted in the context of net clinical benefit

    The Combatants of the Will

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    Consequences of Female Genital Mutilation: Updates and Figures

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    Extract from a document entitled "Female Genital Mutilation".Published with the kind permission of the Institute for Development Training (Chapel Hill, NC) (African Environment: 3-4 (39-40): 93-106

    Pond's extract

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    This apothecary card for Pond's Extract displays an illustration of a man standing in front of the Obelisk. Circa 1870 through 1920

    Lip salve, Pond's extract

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    This apothecary card for Pond's Extract displays an illustration of leaves changing color to red and yellow. “L.R. Eddy, Druggist, Main St. Webster, Mass.,” stamped on the back
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