The Perceived Impact Of Tourism Infrastructure On The Development Of A Heritage Site: The Case Of Petra, Jordan

Tujuan kajian ini dijalankan ádalah untuk meneliti kesan infrastruktur pelancongan terhadap pembangunan tapak warisan bersejarah Petra di Jordan. The purpose of this study was to examine the impact of tourism infrastructure on the development of the heritage site of Petra in Jordan

Gender differences in a Drosophila transcriptomic model of chronic pentylenetetrazole induced behavioral deficit

A male Drosophila model of locomotor deficit induced by chronic pentylenetetrazole (PTZ), a proconvulsant used to model epileptogenesis in rodents, has recently been described. Antiepileptic drugs (AEDs) ameliorate development of this behavioral abnormality. Time-series of microarray profiling of heads of male flies treated with PTZ has shown epileptogenesis-like transcriptomic perturbation in the fly model. Gender differences are known to exist in neurological and psychiatric conditions including epileptogenesis. We describe here the effects of chronic PTZ in Drosophila females, and compare the results with the male model. As in males, chronic PTZ was found found to cause a decreased climbing speed in females. In males, overrepresentation of Wnt, MAPK, TGF-beta, JAK-STAT, Cell communication, and Dorso-Ventral axis formation pathways in downregulated genes was previously described. Of these, female genes showed enrichment only for Dorso-Ventral axis formation. Most significant, ribosomal pathway was uniquely overrepresented in genes downregulated in females. Gender differences thus exist in the Drosophila model. Gender neutral, Dorso-Ventral axis formation may be considered as the candidate causal pathway in chronic pentylenetetrazole induced behavioral deficit. Prior evidence of developmental mechanisms in epileptogenesis underscores the usefulness of fly model. Gender specific pathways may provide a lead for understanding brain dimorphism in neuropsychiatric disorders

PENERAPAN METODE UNIT TEACHING BERBANTU MULTIMEDIA INTERAKTIF UNTUK MENINGKATKAN HASIL BELAJAR SISWA PADA MATA PELAJARAN TIK

Penelitian ini bertujuan untuk: 1)Mengetahui bagaimana mengembangkan multimedia pembelajaran yang digunakan pada proses pembelajaran Unit teaching;2) Mengidentifikasi apakah terdapat perbedaan rerata nilai antara siswa yang mendapatkan penerapan metode Unit Teaching berbantumultimedia dibandingkan dengan siswa yang mendapatkan pembelajaran dengan menggunakan pembelajaran konvensional.Metode yang digunakan dalam penelitian ini adalah metode Kuasi Eksperimen dengan desain penelitian Nonequivalent Control Group Design, sampel yang digunakan adalah kelas VIII A dan kelas VIII B SMP Darul Hikmah Bandung. Mata pelajaran yang dipilih adalah TIK dengan materi Microsoft Excel. Dari hasil pengujian hipotesis menunjukkan bahwa siswa yang pembelajarannya menggunakan model Model Unit Teaching memiliki peningkatan kemampuan Hasil belajar lebih baik daripada siswa yang mendapat pembelajaran secara konvensional serta respon siswa terhadap penerapan model pembelajaran Model Unit Teaching menunjukkan respon yang positif. Pada pengujian gain didapat rerata normalized gain pada kelas eksperimen sebesar 0,58 dengan kategori sedang dan kelas kontrol 0,39 dengan kategori sedang. Dari hasil rerata gain diperoleh bahwa kelas eksperimen memiliki rerata nilai lebih tinggi dibanding kelas kontrol. Kata Kunci :Model Pembelajaran Unit Teaching, Multimedia, Hasil belajar, Mata Pelajaran TIK This study aims to: 1) Knowing how to develop multimedia learning that will be used in the process of cooperative learning Unit Teaching; 1) Identify whether there are differences between the mean scores between children who received application of multimedia - assisted methods Teaching Unit compared whit students who had learning by using conventional leraning; 2) Knowing the students' responses to the learning activities using Unit Teaching. The method which used in this research is Quasi Experimental with Nonequivalent Control Group Design. The sample of this research is students from VIII class A and class VIII B SMP Darul Hikmah Bandung. The choosen subjects is TIK with microsoft excel material. From the results of hypothesis testing showed that students who recieved the application of Unit Teachinghave improved their students’ result of study better than students who received conventional learning and the students' responses to the application of cooperative learning model Unit Teachingshowed a positive responses . The average normalized gain in experiment class is 0,58 and in control class is 0,39 are obtained from gain examination. From the results obtained that the average gain of the experimental class had a mean score higher than the control class.The average gain result shows that experiment class has higher average score than average score in control class. Keywords: Unit Teaching, Multimedia, result of study, TIK Subject

Adherence among parents on under-five childhood immunization schedule: a review

Background: Adherence on under-five childhood immunization schedule has been an area of study that has seldom been explored. Adherence has been the subject of focus in determine if the results of outbreaks and vaccine preventable disease is related to the adherence of the parents to the vaccine schedule. Materials and Methods: A systematic review of articles on the factors of adherence on under-five childhood immunization schedule was performed using various keywords utilizing multiple databases (Medline, PubMed, Science Direct and CINAHL). Studies conducted between 2000 to present, English language and were either observational or qualitative designs were included. Result: Of 45 articles identified, 13 studies were eligible for inclusion. The studies showed that the majority of factors were divided into modifiable and non-modifiable factors. These factors were then further classified into various groups according to its relevance. The modifiable factors were identified as knowledge, vaccine, awareness and perception towards childhood immunization. Whereas non-modifiable factors were sociodemographic factors of parent and child, logistic factors and administration factors. Conclusion: There were many factors identified significantly to be associated with adherence among parents on under-five childhood immunization schedule

Predictors of knowledge, attitude and practice of noise induced hearing loss among workers in an automotive industry in Malaysia

Introduction: Automotive workers are exposed to high level of noise as part of their daily work routine. Determining the predictors of knowledge, attitude and practice of noise induced hearing loss (NIHL) among automotive is important because it may help prevent a serious irreversible disease known as noise induced hearing loss. Methods: A cross sectional study in an automotive plant in Shah Alam, Selangor was conducted from January 2015 to May 2015 among 550 workers with response rate of 83%. Respondents were workers from the operational divisions, selected based on simple random sampling using validated, published (1) and reliable self-administered questionnaire that focused on knowledge, attitude and practice towards NIHL. Results: Logistic Regression was used to determine predictors and the predictors for satisfactory knowledge on noise induced hearing loss were perceived noise exposure as harmful noise (AOR=0.54, 95%CI = 1.02 - 3.41), years in service for more than 10 years (AOR=2.79, 95%CI = 1.71 – 4.56) and had received training on safety (AOR=1.94, 95%CI = 1.12 – 3.36). For satisfactory attitude the predictors were perceived noise exposure as harmful noise (AOR=3.79, 95%CI = 2.36 – 6.10), years in service for more than 10 years (AOR=0.56, 95%CI = 0.34 – 0.83) and tertiary level of education (AOR=3.61, 95%CI = 1.67 - 7.81). As for satisfactory practice the predictors were more than 10 years in service (AOR=2.16, 95%CI = 1.24 – 3.75) and had received training on safety (AOR=1.94, 95%CI = 1.26 – 2.99). Conclusions: The results from this study may be used to set appropriate measures and identify workers who are at risk of developing noise induced hearing loss

Validation of a food frequency questionnaire for assessing Macronutrient and calcium intake in adult Pakistani population

Objective: To develop and validate a food frequency table (FFQ) for use in urban Pakistani population. Study Design: A validation study. Place and Duration of Study: The Aga Khan University, Karachi, from June to November 2008. Methodology: Healthy adult females, aged ≥ 18 years who consented to be included in the study were inducted, while males, unhealthy females, aged below 18 years or who did not consent were excluded. The FFQ was administered once while 4, 24 hours recalls spread over a period of one year were administered as the reference method. Daily intakes for energy, protein, fat, and calcium intake were estimated for both the tools. Crude and energy adjusted correlations for nutrient intakes were computed for the FFQ and mean of 4, 24 hours recalls and serum N-telopeptide of type-I collagen (NTx). Results: The correlation coefficients for the FFQ with mean of 4, 24 hours recall ranged from 0.21 for protein to 0.36 for calcium, while the correlation for nutrient estimates from the FFQ with NTx ranged from -0.07 for calcium to 0.01 for energy. Conclusion: Highly significant correlations were found for nutrient intakes estimated from the FFQ vs. those estimated from the mean of 4, 24 hours recalls but no correlations was found between nutrient estimates from the FFQ and serum NTx levels. FFQ was concluded to be a valid tool for assessing dietary intake of adult females in Pakistan

Bruk av CHADS2 ved behandling av pasienter med atrieflimmer i allmennpraksis

Bakgrunn: Atrieflimmer er en vanlig problemstilling i allmennpraksis. En alvorlig komplikasjon til atrieflimmer er hjerneslag. Derfor er antitrombotisk behandling en viktig del av oppfølgingen av disse pasientene. Som slagprofylakse brukes i dag hovedsakelig warfarin eller ASA. For å velge riktig type antitrombotisk behandling står vurdering av hver enkelt pasients slagrisiko sentralt. CHADS2 er en sjekkliste ved behandling av pasienter med atrieflimmer. Kunnskapsgrunnlag: Det er en utfordring for allmennpraktikere å vurdere slagrisiko, og bruk av risikostratifiseringsskjema bidrar til å kvalitetssikre praksis. CHADS2 er det best etablerte skjemaet og er anbefalt av norske helsemyndigheter samt internasjonale hjerteorganisasjoner. Begrunnet tiltak og metode: Undersøkelsen vår viste at det er varierende bruk av CHADS2 i allmennpraksis, til tross for anbefalingene. Vi har satt sammen et forslag til kombinasjon av flere tiltak som vi tror kan bidra til en vellykket implementering. Hovedtiltaket vårt er en powerpointpresentasjon som gir informasjon om hva CHADS2 er, hvordan det brukes og hvorfor dette kan være et nyttig verktøy. Organisering: En av legene i gruppepraksisen utnevnes til prosjektleder og presenterer CHADS2 for de andre legene i et lunsjmøte eller lignende. En representant for praksisen må få ansvaret for en før- og etterregistrering med tanke på valg av tromboseprofylakse i forhold til risikogruppe, og å kunne fange opp om en endring i praksis vil ha gunstig effekt. Resultater/vurdering: Vi har gjort litteratursøk, kartlegging i allmennpraksis og spesialisthelsetjeneste samt gjort en vurdering av fordeler og ulemper ved tiltaket. På bakgrunn av dette konkluderer vi med at en innføring av CHADS2 i allmennpraksis er faglig godt begrunnet og praktisk gjennomførbart

Advanced design and thermal analysis of a plate heat exchanger for milk cooling in industrial food processing applications

This thesis investigates the advanced design and thermal analysis of a Plate Heat Exchanger (PHE) for milk cooling in industrial food processing. The study focuses on optimizing heat transfer through refined plate geometry and fluid dynamics, using SolidWorks for prototype development and CFD simulations. The results show that the system efficiently reduces milk temperature from 60°C to 4°C using ice water, with a 93.33% temperature drop, indicating scalability for industrial applications. A comparative analysis with Alfa Laval Nordic Oy’s PHE products demonstrated the prototype’s competitive thermal performance, emphasizing its customizability and cost-effectiveness. The study also explored biomimetic design enhancements, such as riblet structures and superhydrophobic surfaces to improve efficiency further. The research highlights the potential of optimized PHE designs for efficient milk cooling in food processing, offering valuable insights for future improvements

Zakah Rate In Islamic Stock Performance Models: Evidence From Indonesia

There are three models commonly used to measure the performance of Islamicstocks, named Treynor Ratio, Sharpe Ratio, and Jansen Index. One component of the three models is risk-free returns which are usually approached with interest rates, whereas interest rates are prohibited in the concept of Islamic finance. This paper will approach a risk-free return with zakat-rate on the Islamic capital market in Indonesia from January 2011 - July 2018, then compare it with a model that uses interest rates. The results obtained by the model with interest rates and zakah-rate in this third model have very high suitability values, so that zakah-rate can be used as an alternative substitute for interest rates in measuring the Islamic stock performance. Beside not contradicting the concept of Islamic economics, calculation of models with zakah-rate is simpler than models with interest rates