803 research outputs found
Pengaruh Pemasaran Internal terhadap Kepuasan Pelanggan Internal Perusahaan pada Pdam Tirta Mayang Kota Jambi
This study aimed is to analyze the effect of Internal Marketing to Internal Customer Satisfaction Company On PDAM TirtaMayang city of Jambi, The population is PDAM TirtaMayang Employees, it is selected randomly as many as 72 people. Results were statistically demonstrated that the Internal Marketing consists of five dimensions together affect the internal customer satisfaction on PDAM TirtaMayang determinant coefficient Jambi with 61.00 percent. Partially there are two variables: the recruitment and empowerment of the five dimensions that have a positive and significant effect, while for the other three variables, is not significant. And the most influential variable is the variable employee empowerment. In addition, given the influence of the independent variables together against internal customer satisfaction on the company PDAM TirtaMayang Jambi City by 61.00 percent, 39.00 percent of course there are still other variables beyond the variables that affect the company's internal customer satisfaction on the taps TirtaMayang Jambi City that need to be investigated further
Cloaking dielectric spherical objects by a shell of metallic nanoparticles
We show that dielectric spheres can be cloaked by a shell of amorphously
arranged metallic nanoparticles. The shell represents an artificial medium with
tunable effective properties that can be adjusted such that the scattered
signals of shell and sphere almost cancel each other. We provide an analytical
model for the cloak design and prove numerically that the cloak operates as
desired. We show that more than 70% of the scattered signal of the sphere can
be suppressed at the design wavelength. Advantages and disadvantages of such a
cloak when compared to other implementations are disclosed.Comment: 14 pages, 6 figure
Silencing of MBD1 and MeCP2 in prostate-cancer-derived PC3 cells produces differential gene expression profiles and cellular phenotypes
Alterations in genomic CpG methylation patterns have been found to be associated with cell transformation and neoplasia. Although it is recognized that methylation of CpG residues negatively regulates gene expression, how the various MBPs (methyl-binding proteins) contribute to this process remains elusive. To determine whether the two well characterized proteins MeCP2 (methyl-CpG-binding protein 2) and MBD1 (methyl-CpG-binding domain 1) have distinct or redundant functions, we employed RNAi (RNA interference) to silence their expression in the prostate cancer-derived PC3cell line, and subsequently compared cell growth, invasion and migration properties of these cell lines in addition to their respective mRNA-expressionprofiles. Cells devoid of MeCP2 proliferated more poorly compared with MBD1-deficient cells and the parental PC3 cells. Enhanced apoptosis was observed in MeCP2-deficient cells, whereas apoptosis in parental and MBD1-deficient cells appeared to be equivalent. Boyden chamber invasion and wound-healing migration assays showed that MBD1-silenced cells were both more invasive and migratory compared with MeCP2-silenced cells. Finally, gene chip microarray analyses showed striking differences in the mRNA-expression profiles obtained from MeCP2- and MBD1-depleted cellsrelative to each other as well as when compared with control cells. The results of the present study suggest that MeCP2 and MBD1 silencing appear to affect cellular processes independently in vivo and that discrete sets of genes involved in cellular proliferation, apoptosis, invasion and migration are targeted by each protein
CFD investigation of a complete floating offshore wind turbine
This chapter presents numerical computations for floating offshore wind turbines for a machine of 10-MW rated power. The rotors were computed using the Helicopter Multi-Block flow solver of the University of Glasgow that solves the Navier-Stokes equations in integral form using the arbitrary Lagrangian-Eulerian formulation for time-dependent domains with moving boundaries. Hydrodynamic loads on the support platform were computed using the Smoothed Particle Hydrodynamics method. This method is mesh-free, and represents the fluid by a set of discrete particles. The motion of the floating offshore wind turbine is computed using a Multi-Body Dynamic Model of rigid bodies and frictionless joints. Mooring cables are modelled as a set of springs and dampers. All solvers were validated separately before coupling, and the loosely coupled algorithm used is described in detail alongside the obtained results
Illusions and Cloaks for Surface Waves
Open access articleEver since the inception of Transformation Optics (TO), new and exciting ideas have been proposed in the field of electromagnetics and the theory has been modified to work in such fields as acoustics and thermodynamics. The most well-known application of this theory is to cloaking, but another equally intriguing application of TO is the idea of an illusion device. Here, we propose a general method to transform electromagnetic waves between two arbitrary surfaces. This allows a flat surface to reproduce the scattering behaviour of a curved surface and vice versa, thereby giving rise to perfect optical illusion and cloaking devices, respectively. The performance of the proposed devices is simulated using thin effective media with engineered material properties. The scattering of the curved surface is shown to be reproduced by its flat analogue (for illusions) and vice versa for cloaks.Engineering and Physical Sciences Research Council (EPSRC
On stability of discretizations of the Helmholtz equation (extended version)
We review the stability properties of several discretizations of the
Helmholtz equation at large wavenumbers. For a model problem in a polygon, a
complete -explicit stability (including -explicit stability of the
continuous problem) and convergence theory for high order finite element
methods is developed. In particular, quasi-optimality is shown for a fixed
number of degrees of freedom per wavelength if the mesh size and the
approximation order are selected such that is sufficiently small and
, and, additionally, appropriate mesh refinement is used near
the vertices. We also review the stability properties of two classes of
numerical schemes that use piecewise solutions of the homogeneous Helmholtz
equation, namely, Least Squares methods and Discontinuous Galerkin (DG)
methods. The latter includes the Ultra Weak Variational Formulation
Recent Advances in Graph Partitioning
We survey recent trends in practical algorithms for balanced graph
partitioning together with applications and future research directions
Non-classical ProIL-1beta activation during mammary gland infection is pathogen-dependent but caspase-1 independent
Infection of the mammary gland with live bacteria elicits a pathogen-specific host inflammatory response. To study these host-pathogen interactions wild type mice, NF-kappaB reporter mice as well as caspase-1 and IL-1beta knockout mice were intramammarily challenged with Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The murine mastitis model allowed to compare the kinetics of the induced cytokine protein profiles and their underlying pathways. In vivo and ex vivo imaging showed that E. coli rapidly induced NF-kappaB inflammatory signaling concomitant with high mammary levels of TNF-alpha, IL-1 alpha and MCP-1 as determined by multiplex analysis. In contrast, an equal number of S. aureus bacteria induced a low NF-kappaB activity concomitant with high mammary levels of the classical IL-1beta fragment. These quantitative and qualitative differences in local inflammatory mediators resulted in an earlier neutrophil influx and in a more extensive alveolar damage post-infection with E. coli compared to S. aureus. Western blot analysis revealed that the inactive proIL-1beta precursor was processed into pathogen-specific IL-1beta fragmentation patterns as confirmed with IL-1beta knockout animals. Additionally, caspase-1 knockout animals allowed to investigate whether IL-1beta maturation depended on the conventional inflammasome pathway. The lack of caspase-1 did not prevent extensive proIL-1beta fragmentation by either of S. aureus or E. coli. These non-classical IL-1beta patterns were likely caused by different proteases and suggest a sentinel function of IL-1beta during mammary gland infection. Thus, a key signaling nodule can be defined in the differential host innate immune defense upon E. coli versus S. aureus mammary gland infection, which is independent of caspase-1
Search for the decay at Belle
We report a search for the rare charmless decay
using a data sample of
pairs collected at the resonance with
the Belle detector at the KEKB asymmetric-energy collider. No
statistically significant signal is found and a 90% confidence-level upper
limit is set on the decay branching fraction as .Comment: 8 pages, 3 figures, submitted to PRD(RC
Evidence of and search for double-charmonium production in and decays
Using data samples of and
events collected with the Belle detector, a first experimental
search has been made for double-charmonium production in the exclusive decays
, where , , , , and . No significant signal is
observed in the spectra of the mass recoiling against the reconstructed
or except for the evidence of production with a
significance of for . The
measured branching fraction \BR(\Upsilon(1S)\rightarrow J/\psi+\chi_{c1}) is
. The
confidence level upper limits on the branching fractions of the other modes
having a significance of less than are determined. These results are
consistent with theoretical calculations using the nonrelativistic QCD
factorization approach.Comment: 12 pages, 4 figures, 1 table. The fit range was extended to include
X(4160) signal according to referee's suggestions. Other results unchanged.
Paper was accepted for publication as a regular article in Physical Review
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