Comparative studies on the effect of environmental pollution on secondary metabolite contents and genotoxicity of two plants in Asir area, Saudi Arabia

Purpose: To investigate the phytochemical contents and genotoxic effects of Ficus carica and Schinus molle grown in healthy and polluted environments in Asir area, Saudi Arabia.Methods: Extracts of the aerial parts of the plants were screened for phytochemical constituents. Genotoxicity tests were carried out in mice using Comet assay, micronucleus test and chromosomal analysis.Results: Extracts of the two plants grown in polluted soil showed elevations in phytochemical and heavy metal contents, when compared with extracts from non-polluted sites. In genotoxicity tests, F. carica and S. molle extracts produced significant increases in the number of micro-nucleated cells in mice, compared to control. Cytotoxicity tests showed that extracts from plants grown in non-polluted environments did not decrease polychromatic erythrocytes (PCE) to normochromatic erythrocytes (NCE) ratio in bone marrow cells, relative to control. Mice in the vehicle control group showed some aberrant metaphases and a few aberrations per hundred metaphases.Conclusion: Pollution has significant effects on phenolic compounds, total flavonoids, and genotoxic potential of the two plants.Keywords:  Ficus carica, Schinus molle, Pollution, Genotoxicity, Total phenolic compounds, Total flavonoid

Phenol removal from aqueous solutions by using H-mordenite and platinum supported H-mordenite

H-Mordenite and platinum supported H-mordenite were prepared and tested to remove phenol from aqueous solutions. The supported mordenite was prepared using wet impregnation method. The physicochemical properties of these prepared samples were characterized by several techniques such as SEM, HR-TEM, X-ray diffraction and N2 adsorption. The effects of temperature, pH, phenol concentration, catalyst amount and UV at 254 nm were studied to obtain the optimum conditions at which best removal occurs. It was seen that the removal using H-mordenite is close to the supported H-mordenite

Dialogues artistiques avec les passés de l'Égypte

De l’architecture aux arts décoratifs et de la peinture au théâtre, ce recueil de textes traite d’œuvres dialoguant avec le patrimoine égyptien dans toutes ses composantes. La notion « d’égyptianisme » se trouve ainsi examinée dans la plus large variété de ses acceptions artistiques, architecturales et critiques, dans le monde occidental comme en Égypte. Les textes révèlent un historicisme artistique de veine égyptienne qui ne se cantonnerait ni à la référence antique, ni au monde occidental : nombreux sont les peintres, les sculpteurs, les cinéastes, les architectes… d’Égypte à avoir intégré des représentations du passé national – pharaonique, copte, médiéval, ottoman, et désormais khédivial ou nassérien – dans leur pratique artistique. À l’encontre de l’image habituelle de l’Égyptomanie, c’est un panorama plus riche et plus diversifié qui prend corps ici à travers divers médias et contextes nationaux. Le présent recueil trouve sa source dans un colloque international organisé à la faveur de la venue à Paris de l’exposition « Le théorème de Néfertiti : itinéraire de l’œuvre d’art, la création des icônes » présentée à l’Institut du monde arabe en 2013. Ce colloque s’est tenu les 26 et 27 juin 2013 en partenariat avec Mathaf : Arab Museum of Modern Art (Doha) sous l’intitulé « L’Égypte en ses miroirs ; art, architecture et critique, à demeure et au-delà (XIXe-XXe siècles) »

Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020

Mapping artificial intelligence adoption in hepatology practice and research: challenges and opportunities in MENA region

BackgroundArtificial intelligence (AI) is increasingly relevant to hepatology, yet real-world adoption in the Middle East and North Africa (MENA) is uncertain. We assessed awareness, use, perceived value, barriers, and policy priorities among hepatology clinicians in the region.MethodsA cross-sectional online survey targeted hepatologists and gastroenterologists across 17 MENA countries. The survey assessed clinical and research applications of AI, perceived benefits, clinical and research use, barriers, ethical considerations, and institutional readiness. Descriptive statistics and thematic analysis were performed.ResultsOf 285 invited professionals, 236 completed the survey (response rate: 82.8%). While 73.2% recognized the transformative potential of AI, only 14.4% used AI tools daily, primarily for imaging analysis and disease prediction. AI tools were used in research by 39.8% of respondents, mainly for data analysis, manuscript writing assistance, and predictive modeling. Major barriers included inadequate training (60.6%), limited AI tool access (53%), and insufficient infrastructure (53%). Ethical concerns focused on data privacy, diagnostic accuracy, and over-reliance on automation. Despite these challenges, 70.3% expressed strong interest in AI training., and 43.6% anticipating routine clinical integration within 1–3 years.ConclusionMENA hepatologists are optimistic about AI but report limited routine use and substantial readiness gaps. Priorities include scalable training, interoperable infrastructure and standards, clear governance with human-in-the-loop safeguards, and region-specific validation to enable safe, equitable implementation