A Survey of Network Optimization Techniques for Traffic Engineering

TCP/IP represents the reference standard for the implementation of interoperable communication networks. Nevertheless, the layering principle at the basis of interoperability severely limits the performance of data communication networks, thus requiring proper configuration and management in order to provide effective management of traffic flows. This paper presents a brief survey related to network optimization using Traffic Engineering algorithms, aiming at providing additional insight to the different alternatives available in the scientific literature

Inorganic arrangement crystal beryllium, lithium, selenium and silicon

The use of inorganic crystals technology has been widely date. Since quartz crystals for watches in the nineteenth century, and common way radio in the early twentieth century, to computer chips with new semiconductor materials. Chemical elements such as beryllium, lithium, selenium and silicon, are widely used in technology. The development of new crystals arising from that arrangement can bring technological advances in several areas of knowledge. The likely difficulty of finding such crystals in nature or synthesized, suggest an advanced study of the subject. A study using computer programs with ab initio method was applied. As a result of the likely molecular structure of the arrangement of a crystal was obtained.Comment: 33 pages, 7 figure

Simulations of Adaptive Optics with a Laser Guide Star for SINFONI

The SINFONI instrument for ESO's VLT combines integral field spectroscopy and adaptive optics (AO). We discuss detailed simulations of the adaptive optics module. These simulations are aimed at assessing the AO module performance, specifically for operations with extended sources and a laser guide star. Simulated point spread function (PSF) images will be used to support scientific preparations and the development of an exposure time calculator, while simulated wavefront sensor measurements will be used to study PSF reconstruction methods. We explain how the adaptive optics simulations work, focusing on the realistic modelling of the laser guide star for a curvature wavefront sensor. The predicted performance of the AO module is discussed, resulting in recommendations for the operation of the SINFONI AO module at the telescope.Comment: 12 pages, 6 figures, to appear in SPIE conference proceedings vol 5490, "Advancements in Adaptive Optics", eds. D. Bonaccini, B.L. Ellerbroek, R. Ragazonni, Glasgow UK, 21-25 June 200

Cell-fate determination by ubiquitin-dependent regulation of translation.

Metazoan development depends on the accurate execution of differentiation programs that allow pluripotent stem cells to adopt specific fates. Differentiation requires changes to chromatin architecture and transcriptional networks, yet whether other regulatory events support cell-fate determination is less well understood. Here we identify the ubiquitin ligase CUL3 in complex with its vertebrate-specific substrate adaptor KBTBD8 (CUL3(KBTBD8)) as an essential regulator of human and Xenopus tropicalis neural crest specification. CUL3(KBTBD8) monoubiquitylates NOLC1 and its paralogue TCOF1, the mutation of which underlies the neurocristopathy Treacher Collins syndrome. Ubiquitylation drives formation of a TCOF1-NOLC1 platform that connects RNA polymerase I with ribosome modification enzymes and remodels the translational program of differentiating cells in favour of neural crest specification. We conclude that ubiquitin-dependent regulation of translation is an important feature of cell-fate determination

A interdisciplinaridade no Colégio Estadual Newton Guimarães

Anais do II Seminário Seminário Estadual PIBID do Paraná: tecendo saberes / organizado por Dulcyene Maria Ribeiro e Catarina Costa Fernandes — Foz do Iguaçu: Unioeste; Unila, 2014A interdisciplinaridade é um processo de integração de disciplinas que possuem um objeto em comum. Dessa forma, este projeto foi realizado com os alunos do primeiro ano do Ensino Médio do Colégio Estadual Newton Guimarães, durante as oficinas de Filosofia do PIBID – Programa Institucional de Bolsas de Iniciação à Docência. Visando a união das matérias de sociologia, filosofia e história, a oficina contou com dois curtas-metragens, sendo um tratando da coisificação do Homem pelo trabalho e o outro sobre a coisificação da natureza pelo Homem. Em seguida, os alunos foram incentivados a pensar esses curtas sob o ponto de vista interdisciplinar das disciplinas supracitas. A pesquisa foi resultado também, de um questionário aplicado a esses aluno

On-sky results of the adaptive optics MACAO for the new IR-spectrograph CRIRES at VLT

The adaptive optics MACAO has been implemented in 6 focii of the VLT observatory, in three different flavors. We present in this paper the results obtained during the commissioning of the last of these units, MACAO-CRIRES. CRIRES is a high-resolution spectrograph, which efficiency will be improved by a factor two at least for point-sources observations with a NGS brighter than R=15. During the commissioning, Strehl exceeding 60% have been observed with fair seeing conditions, and a general description of the performance of this curvature adaptive optics system is done.Comment: SPIE conference 2006, Advances in adaptive optics, 12 pages, 11 figure

The XIIIth Banff Conference on Allograft Pathology: The Banff 2015 Heart Meeting Report: Improving Antibody-Mediated Rejection Diagnostics: Strengths, Unmet Needs, and Future Directions.

The 13th Banff Conference on Allograft Pathology was held in Vancouver, British Columbia, Canada from October 5 to 10, 2015. The cardiac session was devoted to current diagnostic issues in heart transplantation with a focus on antibody-mediated rejection (AMR) and small vessel arteriopathy. Specific topics included the strengths and limitations of the current rejection grading system, the central role of microvascular injury in AMR and approaches to semiquantitative assessment of histopathologic and immunophenotypic indicators, the role of AMR in the development of cardiac allograft vasculopathy, the important role of serologic antibody detection in the management of transplant recipients, and the potential application of new molecular approaches to the elucidation of the pathophysiology of AMR and potential for improving the current diagnostic system. Herein we summarize the key points from the presentations, the comprehensive, open and wide-ranging multidisciplinary discussion that was generated, and considerations for future endeavors