PRETA Air: Hazardous Air Pollutants

This report shows that people living in a 10-county region of southwestern Pennsylvania have a significantly higher than acceptable risk of developing cancer due to exposure to toxic air pollution released by manufacturing processes, energy production and diesel combustionThe Pittsburgh Regional Environmental Threats Analysis Report -- funded by The Heinz Endowments -- analyzes publicly available data on hazardous air pollutants (HAPs), also known as air toxics. Air toxics include approximately 200 pollutants identified by the U.S. Environmental Protection Agency (EPA) as known or suspected to cause cancer or other serious health effects, such as respiratory, neurological and reproductive disorders. The report is the third in a series as part of a project examining major threats to human health and the environment in southwestern Pennsylvania

Operator Product Expansions and Consistency Relations in a O(N) Invariant Fermionic CFT for 2<d<4

A conformally invariant theory of Majorana fermions in 2<d<4 with O(N) symmetry is studied using Operator Product Expansions and consistency relations based on the cancellation of shadow singularities. The critical coupling G_{*} of the theory is calculated to leading order in 1/N. This value is then used to reproduce the O(1/N) correction for the anomalous dimension of the fermion field as evidence for the validity of our approach to conformal field theory in d>2.Comment: 13 pages, Late

A Parameterized Centrality Metric for Network Analysis

A variety of metrics have been proposed to measure the relative importance of nodes in a network. One of these, alpha-centrality [Bonacich, 2001], measures the number of attenuated paths that exist between nodes. We introduce a normalized version of this metric and use it to study network structure, specifically, to rank nodes and find community structure of the network. Specifically, we extend the modularity-maximization method [Newman and Girvan, 2004] for community detection to use this metric as the measure of node connectivity. Normalized alpha-centrality is a powerful tool for network analysis, since it contains a tunable parameter that sets the length scale of interactions. By studying how rankings and discovered communities change when this parameter is varied allows us to identify locally and globally important nodes and structures. We apply the proposed method to several benchmark networks and show that it leads to better insight into network structure than alternative methods.Comment: 11 pages, submitted to Physical Review

Directed Accelerated Growth: Application in Citation Network

In many real world networks, the number of links increases nonlinearly with the number of nodes. Models of such accelerated growth have been considered earlier with deterministic and stochastic number of links. Here we consider stochastic accelerated growth in a network where links are directed. With the number of out-going links following a power law distribution, the results are similar to the undirected case. As the accelerated growth is enhanced, the degree distribution becomes independent of the ``initial attractiveness'', a parameter which plays a key role in directed networks. As an example of a directed model with accelerated growth, the citation network is considered, in which the distribution of the number of outgoing link has an exponential tail. The role of accelerated growth is examined here with two different growth laws.Comment: To be published in the proceedings of Statphys Kolkata V (Physica A

Anti-oxidative cellular protection effect of fasting-induced autophagy as a mechanism for hormesis

The aim of this investigation was to test the hypothesis that fasting-induced augmented lysosomal autophagic turnover of cellular proteins and organelles will reduce potentially harmful lipofuscin (age-pigment) formation in cells by more effectively removing oxidatively damaged proteins. An animal model (marine snail - common periwinkle, Littorina littorea) was used to experimentally test this hypothesis. Snails were deprived of algal food for 7 days to induce an augmented autophagic response in their hepatopancreatic digestive cells (hepatocyte analogues). This treatment resulted in a 25% reduction in the cellular content of lipofuscin in the digestive cells of the fasting animals in comparison with snails fed ad libitum on green alga (Ulva lactuca). Similar findings have previously been observed in the digestive cells of marine mussels subjected to copper-induced oxidative stress. Additional measurements showed that fasting significantly increased cellular health based on lysosomal membrane stability, and reduced lipid peroxidation and lysosomal/cellular triglyceride. These findings support the hypothesis that fasting-induced augmented autophagic turnover of cellular proteins has an anti-oxidative cytoprotective effect by more effectively removing damaged proteins, resulting in a reduction in the formation of potentially harmful proteinaceous aggregates such as lipofuscin. The inference from this study is that autophagy is important in mediating hormesis. An increase was demonstrated in physiological complexity with fasting, using graph theory in a directed cell physiology network (digraph) model to integrate the various biomarkers. This was commensurate with increased health status, and supportive of the hormesis hypothesis. The potential role of enhanced autophagic lysosomal removal of damaged proteins in the evolutionary acquisition of stress tolerance in intertidal molluscs is discussed and parallels are drawn with the growing evidence for the involvement of autophagy in hormesis and anti-ageing processes

A new proof of the Vorono\"i summation formula

We present a short alternative proof of the Vorono\"i summation formula which plays an important role in Dirichlet's divisor problem and has recently found an application in physics as a trace formula for a Schr\"odinger operator on a non-compact quantum graph \mathfrak{G} [S. Egger n\'e Endres and F. Steiner, J. Phys. A: Math. Theor. 44 (2011) 185202 (44pp)]. As a byproduct we give a new proof of a non-trivial identity for a particular Lambert series which involves the divisor function d(n) and is identical with the trace of the Euclidean wave group of the Laplacian on the infinite graph \mathfrak{G}.Comment: Enlarged version of the published article J. Phys. A: Math. Theor. 44 (2011) 225302 (11pp

On Symmetries of Extremal Black Holes with One and Two Centers

After a brief introduction to the Attractor Mechanism, we review the appearance of groups of type E7 as generalized electric-magnetic duality symmetries in locally supersymmetric theories of gravity, with particular emphasis on the symplectic structure of fluxes in the background of extremal black hole solutions, with one or two centers. In the latter case, the role of an "horizontal" symmetry SL(2,R) is elucidated by presenting a set of two-centered relations governing the structure of two-centered invariant polynomials.Comment: 1+13 pages, 2 Tables. Based on Lectures given by SF and AM at the School "Black Objects in Supergravity" (BOSS 2011), INFN - LNF, Rome, Italy, May 9-13 201

Relation of vertebral deformities to bone density, structure, and strength.

Because they are not reliably discriminated by areal bone mineral density (aBMD) measurements, it is unclear whether minimal vertebral deformities represent early osteoporotic fractures. To address this, we compared 90 postmenopausal women with no deformity (controls) with 142 women with one or more semiquantitative grade 1 (mild) deformities and 51 women with any grade 2-3 (moderate/severe) deformities. aBMD was measured by dual-energy X-ray absorptiometry (DXA), lumbar spine volumetric bone mineral density (vBMD) and geometry by quantitative computed tomography (QCT), bone microstructure by high-resolution peripheral QCT at the radius (HRpQCT), and vertebral compressive strength and load-to-strength ratio by finite-element analysis (FEA) of lumbar spine QCT images. Compared with controls, women with grade 1 deformities had significantly worse values for many bone density, structure, and strength parameters, although deficits all were much worse for the women with grade 2-3 deformities. Likewise, these skeletal parameters were more strongly associated with moderate to severe than with mild deformities by age-adjusted logistic regression. Nonetheless, grade 1 vertebral deformities were significantly associated with four of the five main variable categories assessed: bone density (lumbar spine vBMD), bone geometry (vertebral apparent cortical thickness), bone strength (overall vertebral compressive strength by FEA), and load-to-strength ratio (45-degree forward bending ÷ vertebral compressive strength). Thus significantly impaired bone density, structure, and strength compared with controls indicate that many grade 1 deformities do represent early osteoporotic fractures, with corresponding implications for clinical decision making

Elephants and suffering in dusty corners

The following non-refereed paper has been compiled by the editors from the audio transcript and notes provided by Susanna Ferrar for her talk delivered to the Inaugural Totally Huge New Music Festival Conference (Perth: 9 Oct. 2005). The original program note to her presentation reads: I keep talking about this project I\u27m doing, visiting places where the ashes of my grandparents\u27 children ended up, who were all born and raised in Western Australia. As I proceed, adventures seem to be befalling me. Sometimes it seems more important to hang out the washing or change the cat litter. The level of anxiety is high. I\u27m not sure I can cope. I am the artist. I am going to talk. I am chipping away all the bits that aren\u27t part of whatever it is that I am creating. I have sound, I have pictures. There are words. I don\u27t know what they will make in the end. It will be personal, subjective, universal, pretentious, daring, weak. Ferra also played the violin as part of her presentation

Generalized spacetimes defined by cubic forms and the minimal unitary realizations of their quasiconformal groups

We study the symmetries of generalized spacetimes and corresponding phase spaces defined by Jordan algebras of degree three. The generic Jordan family of formally real Jordan algebras of degree three describe extensions of the Minkowskian spacetimes by an extra "dilatonic" coordinate, whose rotation, Lorentz and conformal groups are SO(d-1), SO(d-1,1) XSO(1,1) and SO(d,2)XSO(2,1), respectively. The generalized spacetimes described by simple Jordan algebras of degree three correspond to extensions of Minkowskian spacetimes in the critical dimensions (d=3,4,6,10) by a dilatonic and extra (2,4,8,16) commuting spinorial coordinates, respectively. The Freudenthal triple systems defined over these Jordan algebras describe conformally covariant phase spaces. Following hep-th/0008063, we give a unified geometric realization of the quasiconformal groups that act on their conformal phase spaces extended by an extra "cocycle" coordinate. For the generic Jordan family the quasiconformal groups are SO(d+2,4), whose minimal unitary realizations are given. The minimal unitary representations of the quasiconformal groups F_4(4), E_6(2), E_7(-5) and E_8(-24) of the simple Jordan family were given in our earlier work hep-th/0409272.Comment: A typo in equation (37) corrected and missing titles of some references added. Version to be published in JHEP. 38 pages, latex fil