142 research outputs found
The role of Na+/H+ exchanger in Ca2+ overload and ischemic myocardial damage in hearts from type 2 diabetic db/db mice
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Mitochondrial function after global cardiac ischemia and reperfusion: Influences of organelle isolation protocols
Full text linkDog hearts were made globally ischemic for 1 hr at normothermia, at 28°C, or at normothermia after perfusion with a hyperkalemic cardioplegia solution. After 1 hr of reperfusion mitochondria were isolated from each heart using three protocols involving: processing (homogenization and centrifugation) exclusively in KCl, Tris-EDTA plus albumin (KEA) solution; homogenizing in KEA but washing mitochondria in EDTA-depleted media (KA); or processing exclusively in EDTA-free medium.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41745/1/395_2005_Article_BF01907770.pd
Myocyte membrane and microdomain modifications in diabetes: determinants of ischemic tolerance and cardioprotection
Full text linkGlucose and fatty acid metabolism in infarcted heart from streptozotocin-induced diabetic rats after 2 weeks of tissue remodeling
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Controversies on the sensitivity of the diabetic heart to ischemic injury: the sensitivity of the diabetic heart to ischemic injury is decreased
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