Electronic Structure and Multisite Basicity of the Pyramidal Phosphinidene-Bridged Dimolybdenum Complex[Mo2(η5‑C5H5)(μ‑κ1:κ1,η5‑PC5H4)(η6‑C6H3tBu3)(CO)2(PMe3)]

We thank the DGI of Spain for financial support (Project CTQ2012-33187) and the X-ray unit of the Universidad de Oviedo for acquisition of diffraction data

Mild N-O Bond Cleavage Reactions of a Pyramidalized Nitrosyl Ligand Bridging a Dimolybdenum Center

We thank the DGI of Spain for financial support (Project CTQ2012-33187) and the Consejería de Educación de Asturias for a grant (to A.T.). We also thank the CMC of the Universidad de Oviedo for access to computing facilities, and the X-ray units of the Universities of Oviedo and Santiago de Compostela for acquisition of diffraction data

Insertion and C-C coupling processes in reactions of the unsaturated hydride[W2Cp2(H)(µ-PCy2)(CO)2] with alkynes

We thank the DGI of Spain for financial support (Project CTQ2012-33187) and a grant (to M. F. V.). We also thank the X-Ray unit of the Universidad de Santiago de Compostela, Spain, for collection of diffraction data

Implementation of an information retrieval system within a central knowledge management system

Páginas numeradas: I-XIII, 14-126Estágio realizado na Wipro Portugal SA e orientado pelo Eng.º Hugo NetoTese de mestrado integrado. Engenharia Informática e Computação. Faculdade de Engenharia. Universidade do Porto. 201

Low Speed Telemetry Link System for CubeSat

The main purpose of this project is developing a multidisciplinary Simulation Platform for CubeSats. It will be composed of three differentiated blocks, around which the project is structured: a mechanical simulation platform, a management software and a prototype that will be the base for the future GranaSAT-I. This Master’s Thesis is addressed from a double perspective: on the one hand, the development of a Simulation Platform of great usefulness in an academic environment, as a way to get students from multiple degrees closer to the aerospace world, and particularly to CubeSats, given its current context of peak, being fostered by institutions such as European Space Agency (); on the other hand, in a research environment, providing with a mean to implement new communication algorithms, orbit controllers, and generally speaking, for the development and test of new technologies and techniques, before launching. The development and implementation of this project is performed following methodologies of System Engineering contrasted in the aerospace industry, giving realism and getting the student closer to professional techniques, widely recognized in the job market. Furthermore, the complexity and multidisciplinary scope of this Master’s Thesis allows covering not only the different specialties of the Master in Telecommunication Engineering but also acquiring knowledge and transversal abilities from other fields of the Engineering, such as Mechanical or Aerospace. Besides specific software of each of the mentioned areas, advanced techniques of machining (aluminum milling), manufacturing (solder reflow) or characterization of different devices (lithium batteries, silicon solar cells...) among others, have been analyzed and applied. The result of the exposed culminates with the obtention of a complete and functional simulation environment, which complies with the requirements defined in the preliminary stages, and supposes the finalization of the Master.El objetivo principal del presente proyecto es desarrollar una Plataforma de Simulación multidisciplinar de CubeSats. Estará compuesta de tres bloques diferenciados, en torno a los cuales pivotará el proyecto: una plataforma de simulación mecánica, un software de gestión de y un prototipo de , que constituirá la base del futuro GranaSAT-I. Este Trabajo Fin de Máster se aborda desde una ambiciosa doble perspectiva: por un lado, el desarrollo de una Plataforma de Simulación de amplia utilidad en el ámbito académico, como medio para el acercamiento del alumnado de múltiples titulaciones al mundo aeroespacial y en concreto a los CubeSats, en el contexto de auge actual, fomentado por instituciones como la Agencia Espacial Europea (); en segundo lugar, en el ámbito de investigación, proveyendo de un medio para la implementación de nuevos algoritmos de comunicación, de control orbital y, en general, para el desarrollo y testeo de tecnologías y técnicas novedosas, de manera previa a su lanzamiento. El desarrollo e implementación de este proyecto se lleva a cabo siguiendo metodologías de Ingeniería de Sistemas contrastadas y asentadas en la industria espacial, dotándolo de realismo y acercando al alumno a técnicas profesionales de amplio reconocimiento en el mercado de trabajo. Asimismo, la complejidad y ámbito multidisciplinar de este Trabajo Fin de Máster le permite cubrir, no sólo las diferentes especialidades del Máster de Ingeniería de Telecomunicación, sino también adquirir conocimientos y habilidades transversales o específicos de otros campos de la Ingeniería, como la Mecánica o la Aeroespacial. Así, además de software especialista de cada uno de los campos mencionados, se han analizado y aplicado técnicas avanzadas de mecanizado (fresado de aluminio mediante control numérico), fabricación (soldadura utilizando técnicas de reflow) o caracterización de diferentes dispositivos (baterías de litio, células solares de silicio...), entre otros. El resultado de todo lo expuesto culmina con la obtención de un entorno de simulación completo y funcional, que cumple con los requisitos definidos en etapas iniciales, y con el cual se cierra la etapa universitaria de Máster

Finances and Future Health: Understanding Barriers to First-Generation Student Utilization of Federal Work-Study

First-generation college students experience disproportionate levels of stress, anxiety, and lack of preparation for undergraduate education in comparison to their multi-generational peers in relation to their levels of financial support and literacy. This impacts on their levels of resiliency, their physical and mental wellbeing, academic success, and levels of attrition. This not only has impacts on their health and wellbeing in the present, but can also negatively impact both their health and their career trajectory in the future as well. Using a 2-phase approach, researchers collected both quantitative and qualitative data related to how first-generation EOF students think about the role of financial literacy, and in particular Federal Work Study, as a component of their current and future health status and academic success. Qualitative analysis gave rise to 3 themes related to student feelings of stress, pressure/obligation, lack of preparation, and uncertainty about the role of college education in their current and future lives. Findings are shared in order to better inform and guide institutions of higher education on how to best educate and support their first-generation students, particularly in how to aid these students in improving their financial literacy and financial support to improve resiliency, wellbeing, and academic success

An Inherited Small Microdeletion at 15q13.3 in a Patient with Early- Onset Obsessive-Compulsive Disorder

Copy number variations (CNVs) have been previously associated with several different neurodevelopmen al psychiatric disorders, such as autism, schizophrenia, and attention deficit hyperactivity disorder (ADHD). the present study consisted of pilot genorne-wide screen for CNVs in a cohort of 16 patients with early-onset obsessive-compulsive disorder (OCD) and 2 mentally healthy individuals, using array-based comparative enomic hybridization (aCGH) on 44K arrays. A small rare nal inherited microdeletion (-64 kb) was identified in chromosome 15q13.3 of one male patient with very early onset have OCD. the deletion encompassed part of the FA/IN1 gene, which is involved with the glutamatergic system This finding supports the hypothesis of a complex network of several genes expressed in the brain cant ibuting for h genetic risk of OCD, and also supports the glutamatergic involvement in OCD, which has been previsously reported in the literature.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ São Paulo, Sch Med, Inst & Dept Psychiat, São Paulo, BrazilUniv São Paulo, Inst Math & Stat, Inter Inst Grad Program Bioinformat, São Paulo, BrazilAC Camargo Canc Ctr, Int Res Ctr, São Paulo, BrazilSão Paulo State Univ, Sch Med, São Paulo, BrazilUniversidade Federal de São Paulo, UPIA, São Paulo, BrazilUniversidade Federal de São Paulo, UPIA, São Paulo, BrazilFAPESP: 2008/11537-7CNPq: MCT/CNPq 14/2008Web of Scienc

Risk Assessment for Alzheimer Patients, using GPS and Accelerometers with a Machine Learning Approach

Alzheimer is a pathology with an increasing incidence as people age. The epidemiology of the Alzheimer’s disease crosses every country at later stages in life and, for that motive, has become a major concern as expectancy of life is raising in developed world. The problem, as the disease progresses, becomes, the continuity of the person’s life as normal as possible and the insurance of safety and security for that person. It is known that Alzheimer patients tend to forget about important things such as their identity and location and for that it is important to provide that they become aware of such relevant information for them and for those who could provide them support. It is also known that people with Alzheimer tend to wander and, when that happens, they can get lost and become exposed to danger. The aim of this work is to assess if the person is getting away from usual paths and to monitor if the person falls which becomes riskier while wandering out of usual paths. The usage of GPS makes it possible to keep track of routes and, with the detection of possible deviations, it becomes possible to act accordingly, either issuing warnings for that person and later to carers and family. On the other hand, using machine learning to evaluate usual movements, it is possible to determine if a person falls or endures an excessively quiet position. With those strategies working together it is aimed to ensure safety of a person and request for assistance when high risk is assessed by the technological setup. To address these cases, the proposded setup will be based on a smartphone, together with a smartwatch, both carried by that person, as such devices already provide some needed sensors and GPS receiver while providing processing capabilities

An Inherited Small Microdeletion at 15q13.3 in a Patient\ud with Early- Onset Obsessive-Compulsive Disorder

Copy number variations (CNVs) have been previously associated with several different neurodevelopmental psychiatric\ud disorders, such as autism, schizophrenia, and attention deficit hyperactivity disorder (ADHD). The present study consisted of\ud a pilot genome-wide screen for CNVs in a cohort of 16 patients with early-onset obsessive-compulsive disorder (OCD) and\ud 12 mentally healthy individuals, using array-based comparative genomic hybridization (aCGH) on 44K arrays. A small rare\ud paternal inherited microdeletion (,64 kb) was identified in chromosome 15q13.3 of one male patient with very early onset\ud OCD. The father did not have OCD. The deletion encompassed part of the FMN1 gene, which is involved with the\ud glutamatergic system. This finding supports the hypothesis of a complex network of several genes expressed in the brain\ud contributing for the genetic risk of OCD, and also supports the glutamatergic involvement in OCD, which has been\ud previously reported in the literature.We wish to thank the patients and heathy controls who volunteered to participate in this study.This study was supported by grants to Dras Cappi and Brentani from the Foundation for Research Support of the State of São Paulo (FAPESP); grant number: 2008/11537-7, and from the Brazilian National Council for Scientific and Technological Development (CNPq; protocol number MCT/CNPq 14/2008). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript