Circulating adhesion molecules and arterial stiffness

Aim: VCAM-1 and ICAM-1 are two important members of the immunoglobulin gene superfamily of adhesion molecules, and their potential role as biomarkers of diagnosis, severity and prognosis of cardiovascular disease has been investigated in a number of clinical studies. The aim of the present study was to determine the relationship between circulating ICAM-1 and VCAM-1 levels and aortic stiffness in patients referred for echocardiographic examination. Methods: Aortic distensibility was determined by echocardiography using systolic and diastolic aortic diameters in 63 consecutive patients referred for echocardiography. Venous samples were collected in the morning after a 12-hour overnight fast, and serum concentrations of ICAM-1 and VCAM-1 were measured using commercial enzyme immunoassay kits. Results: Data of a total of 63 participants (mean age 55.6 ± 10.5 years, 31 male) were included in the study. Circulating levels of adhesion molecules were VCAM-1: 12.604 ± 3.904 ng/ml and ICAM-1: 45.417 ± 31.429 ng/ml. We were unable to demonstrate any correlation between indices of aortic stiffness and VCAM-1 and ICAM-1 levels. Conclusion: The role of soluble adhesion molecules in cardiovascular disease has not been fully established and clinical studies show inconsistent results. Our results indicate that levels of circulating adhesion molecules cannot be used as markers of aortic stiffness in patients

Effect of grain alignment on interface trap density of thermally oxidized aligned-crystalline silicon films

The authors report studies of the effect of grain alignment on interface trap density of thermally oxidized aligned-crystalline silicon (ACSi) films by means of capacitance-voltage (C-V) measurements. C-V curves were measured on metal-oxide-semiconductor (MOS) capacitors fabricated on 〈001〉- oriented ACSi films on polycrystalline substrates. From high-frequency C-V curves, the authors calculated a decrease of interface trap density from 2× 1012 to 1× 1011 cm-2 eV-1 as the grain mosaic spread in ACSi films improved from 13.7° to 6.5°. These results demonstrate the effectiveness of grain alignment as a process technique to achieve significantly enhanced performance in small-grained (≤1 μm) polycrystalline Si MOS-type devices. © 2006 American Institute of Physics

Dependence of carrier mobility on grain mosaic spread in 〈001〉-oriented Si films grown on polycrystalline substrates

We studied the dependence of carrier mobility on grain mosaic spread for 〈001〉-oriented, 200-to- 400-nm -thick Si thin films grown on polycrystalline metal substrates. The Hall mobility increased from 1% to 23% of that in bulk single-crystal Si with decreasing grain mosaic spread from 14° to 2°. For the same range of parameters, a model combining intragrain and grain boundary scattering yielded a decrease of the energy barrier height from 0.1 eV to less than 10-3 eV and an accompanying decrease of trap density from 6× 1011 cm-2 to less than 3× 1010 cm-2. These results demonstrate that, for polycrystalline Si films, improving the intergrain alignment is an effective and practical alternative to increasing the grain size to achieve enhanced mobility. © 2005 American Institute of Physics

Microwave performance of high-density bulk MgB2

We have performed microwave measurements on superconducting hot-isostatically- pressed (HIPed) bulk MgB2 using a parallel-plate resonator technique. The high density and strength of the HIPed material allowed preparation of samples with mirror-like surfaces for microwave measurements. The microwave surface resistance decreased by about 40% at 20 K when the root-mean-square surface roughness was reduced from 220 nm to 110 nm through surface-polishing and ion-milling. The surface resistance was independent of surface microwave magnetic field at least up to 4 Oe and below 30 K. We attribute this behavior, and the overall low surface resistance (~0.8 mOhms at 10 GHz and 20 K), to the high density of our samples and the absence of weak links between grains

ICTs and Education in Developing Countries: Do Policies Matter?

This paper analyzes the relationship between information and communication technologies (ICTs) and development in Puerto Rico focusing on education. While other aspects of development are just as important, the lack of progress when it comes to education turn this issue into a big threat to improve other aspects of development, such as economic and social areas. Authors discuss the case of Puerto Rico with the thought that this discussion has relevance in the way ICTs impact areas like the Caribbean and Latin America

Linking macro-level goals to micro-level routines: EHR-enabled transformation of primary care services

Information and communication technologies are known to be instrumental in the enhancement of healthcare management capabilities in developing countries. Turkey - a developing country - has undergone a major healthcare transformation marked by the redesign of primary care delivery and the implementation of a nation-wide Electronic Health Records (EHR) system. In this research, presenting Turkey\u27s case, we investigate the consequences of EHR implementation in developing countries. We argue that to better understand the consequences, we need to link macro-level healthcare goals with micro-level system usage behaviors that actualize the macro-level goals or alternatively result in unintended negative health outcomes. We posit that this linkage is achieved through the meso-level structures, namely the EHR and the organizational context, in which it is embedded. Hence, we examine the EHR\u27s role in this relationship. Our findings indicate that EHR usage both enables and constrains the achievement of clinicians\u27 professional goals in the context of primary care delivery. Moreover, goal alignment between the government agency as the designer of the system and the clinicians influence the outcomes of the EHR-enabled transformation. When the healthcare goals are aligned, the system enables the clinicians to achieve their professional goals and their system usage behaviors converge, contributing to improvements in health outcomes. Contrarily, when the goals are misaligned, the system constrains goal achievement and the clinicians show divergent usage behaviors, including goal abandonment. In turn, goal abandonment may lead to negative consequences and even adversely affect the achievement of population-level healthcare goals in the long run

Limits of the upper critical field in dirty two-gap superconductors

An overview of the theory of the upper critical field in dirty two-gap superconductors, with a particular emphasis on MgB$_2$ is given. We focus here on the maximum $H_{c2}$ which may be achieved by increasing intraband scattering, and on the limitations imposed by weak interband scattering and paramagnetic effects. In particular, we discuss recent experiments which have recently demonstrated ten-fold increase of $H_{c2}$ in dirty carbon-doped films as compared to single crystals, so that the $H_{c2}(0)$ parallel to the ab planes may approach the BCS paramagnetic limit, $H_p[T] = 1.84T_c[K] \simeq 60-70T$. New effects produced by weak interband scattering in the two-gap Ginzburg-Landau equations and $H_{c2}(T)$ in ultrathin MgB$_2$ films are addressed.Comment: Submitted to the special issue of Physica C on MgB$_2$ on Dec. 3, 200

Electrical Conductances and association constants in dilute aqueous NdCl\textsubscript{3} solutions from 298 to 523 K along an isobar of 25 MPa

Electrical measurements were performed in dilute aqueous NdCl3 solutions from 298 to 523 K along the 25 MPa isobar to obtain limiting conductances and association constants. The specific conductance data were estimated using a continuous flow cell and a Markov Chain Monte Carlo (MCMC) correction algorithm. The limiting conductances for the salts in water were derived by regressing the mean spherical approximation (MSA) conductance model and speciation analyses based on the MCMC algorithm and the Deep Earth Water (DEW) model. The limiting conductances derived from the experimental data agree well with a predictive correlation proposed by Smolyakov, Anderko, and Lencka. Only the first association constant between neodymium and chloride could be derived at low temperatures (< 373 K) due to the apparent large statistical uncertainty of the second association constant. Above 373 K, both association constants could be derived and show a reasonable agreement with Migdisov and Williams-Jones and Gammons et al.Comment: 34 pages, 8 figures, to be submitted as an articl