NEW DIMENSIONS AND POTENTIALS FOR AID-UNIVERSITY COOPERATION

Research and Development/Tech Change/Emerging Technologies,

Field-guided proton acceleration at reconnecting X-points in flares

An explicitly energy-conserving full orbit code CUEBIT, developed originally to describe energetic particle effects in laboratory fusion experiments, has been applied to the problem of proton acceleration in solar flares. The model fields are obtained from solutions of the linearised MHD equations for reconnecting modes at an X-type neutral point, with the additional ingredient of a longitudinal magnetic field component. To accelerate protons to the highest observed energies on flare timescales, it is necessary to invoke anomalous resistivity in the MHD solution. It is shown that the addition of a longitudinal field component greatly increases the efficiency of ion acceleration, essentially because it greatly reduces the magnitude of drift motions away from the vicinity of the X-point, where the accelerating component of the electric field is largest. Using plasma parameters consistent with flare observations, we obtain proton distributions extending up to gamma-ray-emitting energies (>1MeV). In some cases the energy distributions exhibit a bump-on-tail in the MeV range. In general, the shape of the distribution is sensitive to the model parameters.Comment: 14 pages, 4 figures, accepted for publication in Solar Physic

Thermo-acoustic wave propagation and reflection near the liquid-gas critical point

We study the thermo-acoustic wave propagation and reflection near the liquid-gas critical point. Specifically, we perform a numerical investigation of the acoustic responses in a near-critical fluid to thermal perturbations based on the same setup of a recent ultrasensitive interferometry measurement in CO2 [Y. Miura et al. Phys. Rev. E 74, 010101(R) (2006)]. The numerical results agree well with the experimental data. New features regarding the reflection pattern of thermo-acoustic waves near the critical point under pulse perturbations are revealed by the proper inclusion of the critically diverging bulk viscosity.Comment: 14 pages, 4 figures, Accepted by PRE (Rapid Communication

A laminar flow model of aerosol survival of epidemic and non-epidemic strains of Pseudomonas aeruginosa isolated from people with cystic fibrosis

Cystic fibrosis (CF) is an inherited multi-system disorder characterised by chronic airway infection with pathogens such as Pseudomonas aeruginosa. Acquisition of P. aeruginosa by patients with CF is usually from the environment, but recent studies have demonstrated patient to patient transmission of certain epidemic strains, possibly via an airborne route. This study was designed to examine the survival of P. aeruginosa within artificially generated aerosols. Survival was effected by the solution used for aerosol generation. Within the aerosols it was adversely affected by an increase in air temperature. Both epidemic and non-epidemic strains of P. aeruginosa were able to survive within the aerosols, but strains expressing a mucoid phenotype had a survival advantage. This would suggest that segregating individuals free of P. aeruginosa from those with chronic P. aeruginosa infection who are more likely to be infected with mucoid strains may help reduce the risk of cross-infection. Environmental factors also appear to influence bacterial survival. Warming and drying the air within clinical areas and avoidance of humidification devices may also be beneficial in reducing the risk of cross-infection

Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life

Background: Older adults are the main recipients of repeat prescriptions for benzodiazepine (BZD) hypnotics. BZDs can impair cognitive function and may not aid sleep when taken continuously for years. This study therefore aimed to determine if withdrawing from BZDs leads to changes in patients' cognitive function, quality of life, mood and sleep. Method: One hundred and ninety-two long-term users of BZD hypnotics, aged [gt-or-equal, slanted]65 years, were identified in 25 general practices. One hundred and four who wished to withdraw were randomly allocated to one of two groups under double-blind, placebo controlled conditions: group A's BZD dose was tapered from week 1 of the trial; group B were given their usual dose for 12 weeks and then it was tapered. An additional group (C) of 35 patients who did not wish to withdraw from BZDs participated as ‘continuers’. All patients were assessed at 0, 12 and 24 weeks and 50% were re-assessed at 52 weeks. Results: Sixty per cent of patients had taken BZDs continuously for >10 years; 27% for >20 years. Of all patients beginning the trial, 80% had successfully withdrawn 6 months later. There was little difference between groups A and B, but these groups differed from continuers (C) in that the performance of the withdrawers on several cognitive/psychomotor tasks showed relative improvements at 24 or 52 weeks. Withdrawers and continuers did not differ in sleep or BZD withdrawal symptoms. Conclusions: These results have clear implications for clinical practice. Withdrawal from BZDs produces some subtle cognitive advantages for older people, yet little in the way of withdrawal symptoms or emergent sleep difficulties. These findings also suggest that, taken long-term, BZDs do not aid sleep

Government Payments: Economic Impact on Southeastern Peanut Farms

Southeastern peanut farms with diversified field crops utilize government payments to supplement market receipts. Production in 2002 represented growing conditions under adverse weather, while 2003 represented optimal conditions. Representative farm analysis provides insight into allocation of market receipts and government payments for meeting variable costs and fixed costs.Crop Production/Industries,

High-risk Sexual Behavior is Associated with Post-Exposure Prophylaxis Non-adherence among Men who have Sex with Men Enrolled in a Combination Prevention Intervention.

Methamphetamine use among men who have sex with men (MSM) is associated with increased HIV prevalence, due to increased engagement in high-risk sexual behavior. Fifty-three HIV-negative, methamphetamine-using MSM were enrolled in a biobehavioral combination prevention intervention in Los Angeles, CA, to assess the feasibility of administering postexposure prophylaxis (PEP) in combination with contingency management (CM) to prevent HIV seroconversion. The study combined a CM behavioral intervention targeting reductions in methamphetamine use with a PEP biomedical intervention for HIV prevention. Those who reported recent exposure to HIV were initiated on tenofovir/emtricitabine- (Truvada)-based PEP (n=35). This secondary analysis sought to determine whether recent and/or lifetime sexual risk taking was associated with PEP adherence. Regression analyses controlling for participant sociodemographics demonstrated that, at baseline, increased number of lifetime sexually transmitted diseases (STDs; Coef.=-0.07; 95% CI=(-0.12) - (-0.01)) and recent episodes of unprotected anal intercourse (UAI; Coef.=-0.01; 95% CI= (-.01) - (-0.002)) were each associated with reductions in medication adherence. Given these associations between baseline sexual risk and PEP adherence, providers working with high-risk MSM may look to target reductions in sexual risk taking; this will reduce direct risk of HIV infection and may work to optimize medication adherence in the case of PEP initiation. Clinicaltrials.gov identifier: NCT00856323

Geometry Optimization of Crystals by the Quasi-Independent Curvilinear Coordinate Approximation

The quasi-independent curvilinear coordinate approximation (QUICCA) method [K. N\'emeth and M. Challacombe, J. Chem. Phys. {\bf 121}, 2877, (2004)] is extended to the optimization of crystal structures. We demonstrate that QUICCA is valid under periodic boundary conditions, enabling simultaneous relaxation of the lattice and atomic coordinates, as illustrated by tight optimization of polyethylene, hexagonal boron-nitride, a (10,0) carbon-nanotube, hexagonal ice, quartz and sulfur at the $\Gamma$-point RPBE/STO-3G level of theory.Comment: Submitted to Journal of Chemical Physics on 7/7/0