Aproximació no lineal i mostratge comprimit

En aquest article donem una pinzellada a un camp relativament nou de la matemàtica, el mostratge comprimit, un terme que correspon a l'expressió compressed sensing o compressive sampling. És una branca del tractament del senyal que d'alguna manera ha aparegut de forma natural associada a un altre gran camp ben modern i present, l'anomenat big data analysis. El mostratge compressiu no tracta pas de la manipulació de grans bases de dades per extreure'n informació útil, sinó justament de no generar informació inútil, innecessària. Per a l'exposició, ens referirem breument a una altra teoria que té entitat per si sola, la teoria de l'aproximació no lineal.In this paper we give an introduction to relatively new field in mathematics, the so called compressed sensing or compressive sampling. It can be presented as a branch of signal analysis, whose appearance is related to another important field, big data analyis. Compressed sensing does not deal with processing big data sets, but rather with sampling methods that do not lead to unnnecessary data. For the sake of the exposition we briefly refer as well to non linear approximation theory

Connections between signal processing and complex analylis

Donem una descripció d'una de les línies de recerca del Grup de Teoria de Funcions de la UAB i la UB, que tracta els problemes de mostreig i interpolació en anàlisi del senyal i les seves connexions amb la teoria de funcions de variable complexa.We describe one of the research lines of the Grup de Teoria de Funcions de la UAB UB, which deals with sampling and interpolation problems in signal analysis and their connections with complex function theory

BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT.

The genetic background of donor and recipient is an important factor determining the outcome of allogeneic hematopoietic SCT (allo-HSCT). We applied whole-genome analysis to investigate genetic variants - other than HLA class I and II - associated with negative outcome after HLA-identical sibling allo-HSCT in a cohort of 110 β-Thalassemic patients. We identified two single-nucleotide polymorphisms (SNPs) in BAT2 (A/G) and BAT3 (T/C) genes, SNP rs11538264 and SNP rs10484558, both located in the HLA class III region, in strong linkage disequilibrium between each other (R2 =0.92). When considered as single SNP, none of them reached a significant association with graft rejection (nominal P<0.00001 for BAT2 SNP rs11538264, and P<0.0001 for BAT3 SNP rs10484558), whereas the BAT2/BAT3 A/C haplotype was present at significantly higher frequency in patients who rejected as compared to those with functional graft (30.0% vs 2.6%, nominal P=1.15 × 10-8; and adjusted P=0.0071). The BAT2/BAT3 polymorphisms and specifically the A/C haplotype may represent a novel immunogenetic factor associated with graft rejection in patients undergoing allo-HSCT

The Thermal Structure of Gas in Pre-Stellar Cores: A Case Study of Barnard 68

We present a direct comparison of a chemical/physical model to multitransitional observations of C18O and 13CO towards the Barnard 68 pre-stellar core. These observations provide a sensitive test for models of low UV field photodissociation regions and offer the best constraint on the gas temperature of a pre-stellar core. We find that the gas temperature of this object is surprisingly low (~7-8 K), and significantly below the dust temperature, in the outer layers (Av < 5 mag) that are traced by C18O and 13CO emission. As shown previously, the inner layers (Av > 5 mag) exhibit significant freeze-out of CO onto grain surfaces. Because the dust and gas are not fully coupled, depletion of key coolants in the densest layers raises the core (gas) temperature, but only by ~1 K. The gas temperature in layers not traced by C18O and 13CO emission can be probed by NH3 emission, with a previously estimated temperature of ~10-11 K. To reach these temperatures in the inner core requires an order of magnitude reduction in the gas to dust coupling rate. This potentially argues for a lack of small grains in the densest gas, presumably due to grain coagulation.Comment: 33 pages, 11 figures, accepted by Astrophysical Journa

Staphylococcus aureus sortase a-mediated incorporation of peptides: Effect of peptide modification on incorporation

The endogenous Staphylococcus aureus sortase A (SrtA) transpeptidase covalently anchors cell wall-anchored (CWA) proteins equipped with a specific recognition motif (LPXTG) into the peptidoglycan layer of the staphylococcal cell wall. Previous in situ experiments have shown that SrtA is also able to incorporate exogenous, fluorescently labelled, synthetic substrates equipped with the LPXTG motif (K(FITC)LPETG-amide) into the bacterial cell wall, albeit at high concentrations of 500 μM to 1 mM. In the present study, we have evaluated the effect of substrate modification on the incorporation efficiency. This revealed that (i) by elongation of LPETG-amide with a sequence of positively charged amino acids, derived from the C-terminal domain of physiological SrtA substrates, the incorporation efficiency was increased by 20-fold at 10 μM, 100 μM and 250 μM; (ii) Substituting aspartic acid (E) for methionine increased the incorporation of the resulting K(FITC)LPMTG-amide approximately three times at all concentrations tested; (iii) conjugation of the lipid II binding antibiotic vancomycin to K(FITC)LPMTG-amide resulted in the same incorporation levels as K(FITC)LPETG-amide, but much more efficient at an impressive 500-fold lower substrate concentration. These newly developed synthetic substrates can potentially find broad applications in for example the in situ imaging of bacteria; the incorporation of antibody recruiting moieties; the targeted delivery and covalent incorporation of antimicrobial compounds into the bacterial cell wall

Construction and Expected Performance of the Hadron Blind Detector for the PHENIX Experiment at RHIC

A new Hadron Blind Detector (HBD) for electron identification in high density hadron environment has been installed in the PHENIX detector at RHIC in the fall of 2006. The HBD will identify low momentum electron-positron pairs to reduce the combinatorial background in the $e^{+}e^{-}$ mass spectrum, mainly in the low-mass region below 1 GeV/c$^{2}$. The HBD is a windowless proximity-focusing Cherenkov detector with a radiator length of 50 cm, a CsI photocathode and three layers of Gas Electron Multipliers (GEM). The HBD uses pure CF$_{4}$ as a radiator and a detector gas. Construction details and the expected performance of the detector are described.Comment: QM2006 proceedings, 4 pages 3 figure

Translation of clinical problems in osteoarthritis into pathophysiological research goals

Osteoarthritis (OA) accounts for more disability among the elderly than any other disease and is associated with an increased mortality rate. The prevalence in Europe will rise in the future since this continent has a strongly ageing population and an obesity epidemic; obesity and age both being major risk factors for OA. No adequate therapeutic options, besides joint replacement, are available, although they are greatly needed and should be acquired by adequate research investments. However, the perspective on OA from a researcher's point of view is not always aligned with the perspective of a patient with OA. Researchers base their views on OA mainly on abnormalities in structure and function while patients consider OA as a collection of symptoms. In this viewpoint paper, we discuss the possibility of translating the most important clinical problems into pathophysiological research goals to facilitate the translation from bench to bedside and vice versa. This viewpoint is the outcome of a dialogue within the 'European League Against Rheumatism study group on OA' and People with Arthritis/Rheumatism across Europe (PARE) representatives

A discourse perspective on creating organizational knowledge: the case of strategizing

This chapter outlines a discursive epistemology of knowledge production through an analysis of the role of time and context in the social construction of organizational insights, outcomes and theories. While the role of time and context has been widely acknowledged in organizational discourse analysis, it has remained unclear what is specific to knowledge generation. Drawing upon a case study of an attempted company acquisition, we illustrate how knowledge is discursively produced and consumed during a process of strategizing. Our analysis shows how knowledge producing processes (e.g. strategizing, theorizing, conceptualizing and hypothesizing) extend both the time horizon of discourses that relate to the future, and the context horizon for discourse(s) that relate to the broader context. This reconstructs the tapestry of interwoven discourses that make up a local discourse and enable new managerial knowledge to be produced

The sardinian bitter honey: From ancient healing use to recent findings

Sardinian bitter honey, obtained from the autumnal flowering of the strawberry tree (Arbutus unedo L.), has an old fame and tradition in popular use, especially as a medicine. Its knowledge dates back over 2000 years, starting from the Greeks and Romans to the present day. There are many literary references from illustrious personalities of the past such as Cicero, Horace, Virgil, and Dioscorides, until recent times, associated with the peculiar anomaly of its taste, which lends itself to literary and poetic metaphors. The curiosity of its bitter taste is also what led to the first studies starting in the late 1800s, aimed to reveal its origin. Other studies on its botanical source and characteristics have been carried out over time, up to the most recent investigations, which have confirmed its potential for use in the medical field, thanks to its antioxidant, antiradical, and cancer-preventing properties. These benefits have been associated with its phenolic component and in particular with the prevailing phenolic acid (homogentisic acid). Later, other strawberry tree honeys from the Mediterranean area have also shown the same properties. However, Sardinian bitter honey maintains its geographical and historical identity, which is recognized by other Mediterranean cultures

How the infestation level of Varroa destructor affects the distribution pattern of multi-infested cells in worker brood of Apis mellifera

The mite Varroa destructor, the main ectoparasite of honey bees, is a threat to apiculture worldwide. Understanding the ecological interactions between Varroa and honeybees is fundamental for reducing mite impact in apiaries. This work assesses bee colonies with various Varroa infestation levels in apiaries to determine: (1) the relationship between multi-infested brood cells and brood infestation level, (2) the damage caused by Varroa to parasitized honey bee pupae, and (3) mite reproduction rate at various infestation levels. Data were collected from 19 worker brood combs, each from a different colony, ranging from 160 to 1725 (mean = 706) sealed cells per comb. Mite distribution was aggregated, ranging from about 2% to 74% infested cells per comb. The percentage of cells invaded by one, two, three, four, or more than four foundress mites, as a function of infestation level, was estimated by five highly significant (p &lt; 0.0001) second-degree polynomial regression equations. The correction factors found could increase the precision of prediction models. Varroa fertility and adult bee longevity decreased as multi-infestation levels increased, and the implications of this relationship are discussed. Finally, these findings could improve sampling methods and the timing of mite treatments in apiaries, thus favoring sustainable management strategies