21,347 research outputs found
Role of stable modes in driven shear-flow turbulence
A linearly unstable, sinusoidal shear flow is examined in the
gyrokinetic framework in both the linear and nonlinear regimes. In the linear
regime, it is shown that the eigenmode spectrum is nearly identical to
hydrodynamic shear flows, with a conjugate stable mode found at every unstable
wavenumber. In the nonlinear regime, turbulent saturation of the instability is
examined with and without the inclusion of a driving term that prevents
nonlinear flattening of the mean flow, and a scale-independent radiative
damping term that suppresses the excitation of conjugate stable modes. A simple
fluid model for how momentum transport and partial flattening of the mean flow
scale with the driving term is constructed, from which it is shown that, except
at high radiative damping, stable modes play an important role in the turbulent
state and yield significantly improved quantitative predictions when compared
with corresponding models neglecting stable modes.Comment: 34 pages pre-print format, 13 figures, submitted to Physics of
Plasma
Dorsalization of the neural tube by the non-neural ectoderm
The patterning of cell types along the dorsoventral axis of the spinal cord requires a complex set of inductive signals. While the chordamesoderm is a well-known source of ventralizing signals, relatively little is known about the cues that induce dorsal cell types, including neural crest. Here, we demonstrate that juxtaposition of the non-neural and neural ectoderm is sufficient to induce the expression of dorsal markers, Wnt-1, Wnt-3a and Slug, as well as the formation of neural crest cells. In addition, the competence of neural plate to express Wnt-1 and Wnt-3a appears to be stage dependent, occurring only when neural tissue is taken from stage 8–10 embryos but not from stage 4 embryos, regardless of the age of the non-neural ectoderm. In contrast to the induction of Wnt gene expression, neural crest cell formation and Slug expression can be induced when either stage 4 or stage 8–10 neural plates are placed in contact with the non-neural ectoderm. These data suggest that the non-neural ectoderm provides a signal (or signals) that specifies dorsal cell types within the neural tube, and that the response is dependent on the competence of the neural tissue
A-STAR: The All-Sky Transient Astrophysics Reporter
The small mission A-STAR (All-Sky Transient Astrophysics Reporter) aims to
locate the X-ray counterparts to ALIGO and other gravitational wave detector
sources, to study the poorly-understood low luminosity gamma-ray bursts, and to
find a wide variety of transient high-energy source types, A-STAR will survey
the entire available sky twice per 24 hours. The payload consists of a coded
mask instrument, Owl, operating in the novel low energy band 4-150 keV, and a
sensitive wide-field focussing soft X-ray instrument, Lobster, working over
0.15-5 keV. A-STAR will trigger on ~100 GRBs/yr, rapidly distributing their
locations.Comment: Accepted for the European Astronomical Society Publications Series:
Proceedings of the Fall 2012 Gamma-Ray Burst Symposium held in Marbella,
Spain, 8-12 Oct 201
The nature of supernovae 2010O and 2010P in Arp 299 - I. Near-infrared and optical evolution
We present near-infrared and optical photometry, plus optical spectroscopy of
two stripped-envelope supernovae (SNe) 2010O and 2010P that exploded in two
different components of an interacting luminous infrared galaxy Arp 299 within
only a few days of one another. SN 2010O is found to be photometrically and
spectroscopically similar to many normal Type Ib SNe and our multiwavelength
observations of SN 2010P suggest it to be a Type IIb SN. No signs of clear
hydrogen features or interaction with the circumstellar medium are evident in
the optical spectrum of SN 2010P. We derive estimates for the host galaxy
line-of-sight extinctions for both SNe, based on both light-curve and
spectroscopic comparison finding consistent results. These methods are also
found to provide much more robust estimates of the SN host galaxy reddening
than the commonly used empirical relations between extinction and equivalent
width of Na I D absorption features. The SN observations also suggest that
different extinction laws are present in different components of Arp 299. For
completeness, we study high-resolution pre-explosion images of Arp 299 and find
both SNe to be close to, but not coincident with, extended sources that are
likely massive clusters. A very simple model applied to the bolometric light
curve of SN 2010O implies a rough estimate for the explosion parameters of
erg,
M and M.Comment: 16 pages, 11 figures. Minor changes in text from v1. Published in
MNRA
Physical activity is prospectively associated with adolescent nonalcoholic fatty liver disease
Objectives: The aim of the present study was to assess whether objectively measured physical activity at mean ages 12 and 14 years are prospectively associated with ultrasound scan liver fat and stiffness (alanine aminotransferase, aspartate aminotransferase [AST], and [gamma]-glutamyl transferase [GGT]) assessed at mean age 17.8 years.
Methods: Participants were from the Avon Longitudinal Study of Parents and Children. Total physical activity (counts per minute) and minutes of moderate to vigorous physical activity (MVPA) were measured using ActiGraph accelerometers at mean ages 12 and 14 years.
Results: Greater total physical activity and MVPA at ages 12 and 14 years were associated with lower odds of liver fat and lower GGT levels at mean age 17.8 years, such as per 15-minute increase in daily MVPA at age 12 years, the confounder adjusted odds ratio of liver fat was 0.47 (95% confidence interval [CI] 0.27–0.84). Associations attenuated after additional adjustment for fat mass as a potential confounder (eg, per 15-minute increase in daily MVPA at age 12 years, the odds ratio of liver fat attenuated to 0.65 [95% CI 0.35–1.21]) or a potential mediator (eg, per 15-minute increase in daily MVPA at age 12 years the odds ratio of liver fat attenuated to 0.59 [95% CI 0.32–1.09]). Results did not further attenuate after additional adjustment for insulin resistance. There was some evidence that greater total physical activity and MVPA at age 12 years were associated with the higher AST levels.
Conclusions: Adolescents who were more active in childhood have lower odds of fatty liver and lower GGT levels. These findings are likely to be, at least in part, explained by adiposity
Soft-tissue specimens from pre-European extinct birds of New Zealand
We provide the first complete review of soft tissue remains from New Zealand birds that became extinct prior to European settlement (c. AD 1800). These rare specimens allow insights into the anatomy and appearance of the birds that are not attainable from bones. Our review includes previously unpublished records of ‘lost’ specimens, and descriptions of recently discovered specimens such as the first evidence of soft tissues from the South Island goose (Cnemiornis calcitrans). Overall, the soft tissue remains are dominated by moa (with specimens from each of the six genera), but also include specimens from Finsch's duck (Chenonetta finschi) and the New Zealand owlet-nightjar (Aegotheles novaezealandiae). All desiccated soft tissue specimens that have radiocarbon or stratigraphic dates are late Holocene in age, and most have been found in the semi-arid region of Central Otago
Selective Use of Pericardial Window and Drainage as Sole Treatment for Hemopericardium from Penetrating Chest Trauma
Background
Penetrating cardiac injuries (PCIs) are highly lethal, and a sternotomy is considered mandatory for suspected PCI. Recent literature suggests pericardial window (PCW) may be sufficient for superficial cardiac injuries to drain hemopericardium and assess for continued bleeding and instability. This study objective is to review patients with PCI managed with sternotomy and PCW and compare outcomes.
Methods
All patients with penetrating chest trauma from 2000 to 2016 requiring PCW or sternotomy were reviewed. Data were collected for patients who had PCW for hemopericardium managed with only pericardial drain, or underwent sternotomy for cardiac injuries grade 1–3 according to the American Association for the Surgery of Trauma (AAST) Cardiac Organ Injury Scale (OIS). The PCW+drain group was compared with the Sternotomy group using Fisher’s exact and Wilcoxon rank-sum test with P\u3c0.05 considered statistically significant.
Results
Sternotomy was performed in 57 patients for suspected PCI, including 7 with AAST OIS grade 1–3 injuries (Sternotomy group). Four patients had pericardial injuries, three had partial thickness cardiac injuries, two of which were suture-repaired. Average blood drained was 285mL (100–500 mL). PCW was performed in 37 patients, and 21 had hemopericardium; 16 patients proceeded to sternotomy and 5 were treated with pericardial drainage (PCW+drain group). All PCW+drain patients had suction evacuation of hemopericardium, pericardial lavage, and verified bleeding cessation, followed by pericardial drain placement and admission to intensive care unit (ICU). Average blood drained was 240mL (40–600 mL), and pericardial drains were removed on postoperative day 3.6 (2–5). There was no significant difference in demographics, injury mechanism, Revised Trauma Score exploratory laparotomies, hospital or ICU length of stay, or ventilator days. No in-hospital mortality occurred in either group.
Conclusions
Hemodynamically stable patients with penetrating chest trauma and hemopericardium may be safely managed with PCW, lavage and drainage with documented cessation of bleeding, and postoperative ICU monitoring.
Level of evidence
Therapeutic study, level IV
Evolution of population with sexual and asexual reproduction in changing environment
Using a lattice model based on Monte Carlo simulations, we study the role of
the reproduction pattern on the fate of an evolving population. Each individual
is under the selection pressure from the environment and random mutations. The
habitat ("climate") is changing periodically. Evolutions of populations
following two reproduction patterns are compared, asexual and sexual. We show,
via Monte Carlo simulations, that sexual reproduction by keeping more
diversified populations gives them better chances to adapt themselves to the
changing environment. However, in order to obtain a greater chance to mate, the
birth rate should be high. In the case of low birth rate and high mutation
probability there is a preference for the asexual reproduction.Comment: 11 pages including figs., for Int. J. Mod. Phys. C 15, issue 2 (2004
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