Aeroengine performance prediction using a physical-embedded data-driven method

Accurate and efficient prediction of aeroengine performance is of paramount importance for engine design, maintenance, and optimization endeavours. However, existing methodologies often struggle to strike an optimal balance among predictive accuracy, computational efficiency, modelling complexity, and data dependency. To address these challenges, we propose a strategy that synergistically combines domain knowledge from both the aeroengine and neural network realms to enable real-time prediction of engine performance parameters. Leveraging aeroengine domain knowledge, we judiciously design the network structure and regulate the internal information flow. Concurrently, drawing upon neural network domain expertise, we devise four distinct feature fusion methods and introduce an innovative loss function formulation. To rigorously evaluate the effectiveness and robustness of our proposed strategy, we conduct comprehensive validation across two distinct datasets. The empirical results demonstrate :(1) the evident advantages of our tailored loss function; (2) our model's ability to maintain equal or superior performance with a reduced parameter count; (3) our model's reduced data dependency compared to generalized neural network architectures; (4)Our model is more interpretable than traditional black box machine learning methods

Recent Advances on Sorting Methods of High-Throughput Droplet-Based Microfluidics in Enzyme Directed Evolution

Droplet-based microfluidics has been widely applied in enzyme directed evolution (DE), in either cell or cell-free system, due to its low cost and high throughput. As the isolation principles are based on the labeled or label-free characteristics in the droplets, sorting method contributes mostly to the efficiency of the whole system. Fluorescence-activated droplet sorting (FADS) is the mostly applied labeled method but faces challenges of target enzyme scope. Label-free sorting methods show potential to greatly broaden the microfluidic application range. Here, we review the developments of droplet sorting methods through a comprehensive literature survey, including labeled detections [FADS and absorbance-activated droplet sorting (AADS)] and label-free detections [electrochemical-based droplet sorting (ECDS), mass-activated droplet sorting (MADS), Raman-activated droplet sorting (RADS), and nuclear magnetic resonance-based droplet sorting (NMR-DS)]. We highlight recent cases in the last 5 years in which novel enzymes or highly efficient variants are generated by microfluidic DE. In addition, the advantages and challenges of different sorting methods are briefly discussed to provide an outlook for future applications in enzyme DE

Bioinspired and bristled microparticles for ultrasensitive pressure and strain sensors

Biological sensory organelles are often structurally optimized for high sensitivity. Tactile hairs or bristles are ubiquitous mechanosensory organelles in insects. The bristle features a tapering spine that not only serves as a lever arm to promote signal transduction, but also a clever design to protect it from mechanical breaking. A hierarchical distribution over the body further improves the signal detection from all directions. We mimic these features by using synthetic zinc oxide microparticles, each having spherically-distributed, high-aspect-ratio, and high-density nanostructured spines resembling biological bristles. Sensors based on thin films assembled from these microparticles achieve static-pressure detection down to 0.015 Pa, sensitivity up to 121 kPa−1, and a strain gauge factor \u3e104, showing supreme overall performance. Other properties including a robust cyclability \u3e2000, fast response time ~7 ms, and low-temperature synthesis compatible to various integrations further indicate the potential of this sensor technology in applying to wearable technologies and human interfaces

Model Will Tell: Training Membership Inference for Diffusion Models

Diffusion models pose risks of privacy breaches and copyright disputes, primarily stemming from the potential utilization of unauthorized data during the training phase. The Training Membership Inference (TMI) task aims to determine whether a specific sample has been used in the training process of a target model, representing a critical tool for privacy violation verification. However, the increased stochasticity inherent in diffusion renders traditional shadow-model-based or metric-based methods ineffective when applied to diffusion models. Moreover, existing methods only yield binary classification labels which lack necessary comprehensibility in practical applications. In this paper, we explore a novel perspective for the TMI task by leveraging the intrinsic generative priors within the diffusion model. Compared with unseen samples, training samples exhibit stronger generative priors within the diffusion model, enabling the successful reconstruction of substantially degraded training images. Consequently, we propose the Degrade Restore Compare (DRC) framework. In this framework, an image undergoes sequential degradation and restoration, and its membership is determined by comparing it with the restored counterpart. Experimental results verify that our approach not only significantly outperforms existing methods in terms of accuracy but also provides comprehensible decision criteria, offering evidence for potential privacy violations.Comment: 18 pages, 6 figures, 7 table

OPT: One-shot Pose-Controllable Talking Head Generation

One-shot talking head generation produces lip-sync talking heads based on arbitrary audio and one source face. To guarantee the naturalness and realness, recent methods propose to achieve free pose control instead of simply editing mouth areas. However, existing methods do not preserve accurate identity of source face when generating head motions. To solve the identity mismatch problem and achieve high-quality free pose control, we present One-shot Pose-controllable Talking head generation network (OPT). Specifically, the Audio Feature Disentanglement Module separates content features from audios, eliminating the influence of speaker-specific information contained in arbitrary driving audios. Later, the mouth expression feature is extracted from the content feature and source face, during which the landmark loss is designed to enhance the accuracy of facial structure and identity preserving quality. Finally, to achieve free pose control, controllable head pose features from reference videos are fed into the Video Generator along with the expression feature and source face to generate new talking heads. Extensive quantitative and qualitative experimental results verify that OPT generates high-quality pose-controllable talking heads with no identity mismatch problem, outperforming previous SOTA methods.Comment: Accepted by ICASSP202