33 research outputs found

    The Impact of Systematic Edits in History Slicing

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    While extracting a subset of a commit history, specifying the necessary portion is a time-consuming task for developers. Several commit-based history slicing techniques have been proposed to identify dependencies between commits and to extract a related set of commits using a specific commit as a slicing criterion. However, the resulting subset of commits become large if commits for systematic edits whose changes do not depend on each other exist. We empirically investigated the impact of systematic edits on history slicing. In this study, commits in which systematic edits were detected are split between each file so that unnecessary dependencies between commits are eliminated. In several histories of open source systems, the size of history slices was reduced by 13.3-57.2% on average after splitting the commits for systematic edits.Comment: 5 pages, MSR 201

    人工酸素運搬体としての(ヘモグロビン-アルブミン)クラスターの合成

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    【学位授与の要件】中央大学学位規則第4条第1項【論文審査委員主査】小松 晃之 (中央大学理工学部教授)【論文審査委員副査】石塚 盛雄(中央大学理工学部教授)、古田 直紀(中央大学理工学部教授)、箕浦 高子(中央大学理工学部准教授)、中村 暢文(東京農工大学大学院工学研究院教授)博士(工学)中央大

    Lower prefrontal blood flow associated with intraindividual weakness in successive processing: a neurocognitive study of pediatric moyamoya disease

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    OBJECTIVE: Selective intraindividual weakness in successive processing, which is a unique verbal working memory scale included in the Das-Naglieri Cognitive Assessment System (CAS), is considered one of the intrinsic neurocognitive characteristics in pediatric moyamoya disease (MMD). The aim of the study was to elucidate the association between cerebral blood flow (CBF) and weakness in successive processing, and to identify regions related to the weakness. METHODS: The present cross-sectional study included children who had been diagnosed with MMD and were assessed using neuropsychological tests before surgery between June 2016 and December 2023. According to the CAS manual, intraindividual difference was calculated by subtracting the mean of the 4 standard scores from each standard score. Each patient was classified as either manifesting “intraindividual weakness in successive processing” (intraindividual difference of successive processing < 0) or not (intraindividual difference of successive processing ≥ 0), and CBF acquired with resting-state SPECT was compared between groups. Three-dimensional stereotactic surface projection (3D-SSP) was also used for topographical comparison of CBF. RESULTS: Of 51 children (mean age ± SD at admission 8.0 ± 2.6 years) who underwent preoperative neuropsychological tests, 43 were included in the CBF analysis. Both standard scores and intraindividual difference of the CAS significantly varied across 4 domains (p = 0.006 and p < 0.001, respectively), and those of successive processing were the lowest. Of the children analyzed, 35 (68.7%) were classified as having intraindividual weakness in successive processing. Multiple logistic regression analysis revealed the severest ischemic grade was significantly associated with intraindividual weakness in successive processing (OR 5.49 [95% CI 1.12-27.06]). Three-dimensional SSP analysis demonstrated a significant CBF decrease in the left dorsolateral and medial prefrontal cortexes in the children showing intraindividual weakness in successive processing compared with those who did not. CONCLUSIONS: Intraindividual weakness in successive processing typical of MMD might be associated with reduced CBF in the dorsolateral and medial prefrontal cortex, predominantly in the left hemisphere. Further studies in this area could contribute to the improvement of long-term social outcomes for patients with MMD

    Neuroimaging at 7 Tesla: a pictorial narrative review

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    Neuroimaging using the 7-Tesla (7T) human magnetic resonance (MR) system is rapidly gaining popularity after being approved for clinical use in the European Union and the USA. This trend is the same for functional MR imaging (MRI). The primary advantages of 7T over lower magnetic fields are its higher signal-to-noise and contrast-to-noise ratios, which provide high-resolution acquisitions and better contrast, making it easier to detect lesions and structural changes in brain disorders. Another advantage is the capability to measure a greater number of neurochemicals by virtue of the increased spectral resolution. Many structural and functional studies using 7T have been conducted to visualize details in the white matter and layers of the cortex and hippocampus, the subnucleus or regions of the putamen, the globus pallidus, thalamus and substantia nigra, and in small structures, such as the subthalamic nucleus, habenula, perforating arteries, and the perivascular space, that are difficult to observe at lower magnetic field strengths. The target disorders for 7T neuroimaging range from tumoral diseases to vascular, neurodegenerative, and psychiatric disorders, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, epilepsy, major depressive disorder, and schizophrenia. MR spectroscopy has also been used for research because of its increased chemical shift that separates overlapping peaks and resolves neurochemicals more effectively at 7T than a lower magnetic field. This paper presents a narrative review of these topics and an illustrative presentation of images obtained at 7T. We expect 7T neuroimaging to provide a new imaging biomarker of various brain disorders

    Synthesis of Hemoglobin-Albumin Clusters as an Artificial O2-Carrier

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    Properties of Magnetic Garnet Films for Flexible Magneto-Optical Indicators Fabricated by Spin-Coating Method

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    Non-destructive testing using a magneto-optical effect is a high-resolution non-destructive inspection technique for a metallic structure. It is able to provide high-spatial resolution images of defects. Previously, it has been difficult to fabricate flexible magneto-optical sensors because thermal treatment is necessary to crystallize the magnetic garnet. Therefore, it was not possible to apply magneto-optical imaging to complicated shapes in a test subject, such as a curved surface. In this study, we developed a new process for deposition of the magnetic garnet on the flexible substrate by applying the magnetic garnet powders that have already undergone crystallization. In this new process, as it does not require thermal treatment after deposition, flexible substrates with low heat resistance can be used. In this paper, we report our observations of the optical properties, magnetic hysteresis loop, crystallizability and density of the particles on the flexible substrate deposited by the spin-coating method
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