Functioning and disability in multiple sclerosis from the patient perspective

Multiple sclerosis (MS) has a great impact on functioning and disability. The perspective of those who experience the health problem has to be taken into account to obtain an in-depth understanding of functioning and disability. The objective was to describe the areas of functioning and disability and relevant contextual factors in MS from the patient perspective. A qualitative study using focus group methodology was performed. The sample size was determined by saturation. The focus groups were digitally recorded and transcribed verbatim. The meaning condensation procedure was used for data analysis. Identified concepts were linked to International Classification of Functioning, Disability and Health (ICF) categories according to established linking rules. Six focus groups with a total of 27 participants were performed. In total, 1327 concepts were identified and linked to 106 ICF categories of the ICF components Body Functions, Activities and Participation and Environmental Factors. This qualitative study reports on the impact of MS on functioning and disability from the patient perspective. The participants in this study provided information about all physical aspects and areas of daily life affected by the disease, as well as the environmental factors influencing their lives

Especies de caza: procesos de extinción ocultos tras elevados tamaños de censo

Management of game species may involve a risk of alteration of their genetic properties. Local adaptations may be disrupted if artificially selected individuals from farms or those belonging to distant geographical areas are introduced to increase population density or trophy “quality”. In Spain, red deer (Cervus elaphus) from different European subspecies have been introduced to increase the size of trophies (antlers) of local populations. Legislation against these introductions is not effective for various reasons, and once the individuals are in the Iberian peninsula it is virtually impossible to prevent their spreading throughout the whole territory without a genetic tool to distinguish between autochthonous and foreign specimens. We have developed such a genetic test and propose a strategy to dissuade land–owners from importing foreign deer. Since deer are bred mainly for their antlers, our strategy is based on an agreement with the National Trophy Body in Spain which rejects trophies from foreign populations. Rejection decreases the value of the trophy so that it becomes more profitable to produce autochthonous deer. Using such a strategy at some critical step in the production or commercialization process may be a good model to apply in protecting genetic properties of exploited species.La gestión de las especies de caza puede conllevar riesgos de alteración de sus propiedades genéticas. Las adaptaciones locales pueden deteriorarse si ejemplares producidos mediante selección artificial en granjas o procedentes de áreas geográficas distantes, son introducidos para aumentar la densidad poblacional o la "calidad" de los trofeos de caza. En España, se han introducido ejemplares de ciervo ibérico (Cervus elaphus) procedentes de distintas subespecies europeas para aumentar así el tamaño de las cuernas (trofeos de caza) de las poblaciones autóctonas. La legislación contra este tipo de introducciones no es eficaz por diversos motivos y, una vez introducidos los ejemplares en la península ibérica, es prácticamente imposible prevenir su dispersión por todo el territorio sin contar con herramientas genéticas que permitan diferenciar los ejemplares autóctonos de los foráneos. Nosotros hemos desarrollado un test genético para este fin, y hemos propuesto una estrategia para disuadir a lospropietarios de llevar a cabo la importación de ejemplares foráneos. Puesto que los ciervos se crían fundamentalmente por su cornamenta como trofeo de caza, nuestra estrategia se ha basado en un acuerdo con la Junta Nacional de Homologación de Trofeos de Caza, para que ésta rechace los trofeos pertenecientes a ejemplares foráneos. Este rechazo reduce el valor de los ejemplares procedentes de otras poblaciones y favorece la producción de ciervo autóctono. Sugerimos que la utilización de estrategias de este tipo en puntos clave de procesos de producción o comercialización, puede ser un buen modelo a aplicar para proteger las propiedades genéticas de las especies sujetas a explotación por el hombre

Developing core sets for persons following amputation based on the International Classification of Functioning, Disability and Health as a way to specify functioning

Amputation is a common late stage sequel of peripheral vascular disease and diabetes or a sequel of accidental trauma, civil unrest and landmines. The functional impairments affect many facets of life including but not limited to: Mobility; activities of daily living; body image and sexuality. Classification, measurement and comparison of the consequences of amputations has been impeded by the limited availability of internationally, multiculturally standardized instruments in the amputee setting. The introduction of the International Classification of Functioning, Disability and Health (ICF) by the World Health Assembly in May 2001 provides a globally accepted framework and classification system to describe, assess and compare function and disability. In order to facilitate the use of the ICF in everyday clinical practice and research, ICF core sets have been developed that focus on specific aspects of function typically associated with a particular disability. The objective of this paper is to outline the development process for the ICF core sets for persons following amputation. The ICF core sets are designed to translate the benefits of the ICF into clinical routine. The ICF core sets will be defined at a Consensus conference which will integrate evidence from preparatory studies, namely: (a) a systematic literature review regarding the outcome measures of clinical trails and observational studies, (b) semi-structured patient interviews, (c) international experts participating in an internet-based survey, and (d) cross-sectional, multi-center studies for clinical applicability. To validate the ICF core sets field-testing will follow. Invitation for participation: The development of ICF Core Sets is an inclusive and open process. Anyone who wishes to actively participate in this process is invited to do so

Game species: extinction hidden by census numbers

Management of game species may involve a risk of alteration of their genetic properties. Local adaptations may be disrupted if artificially selected individuals from farms or those belonging to distant geographical areas are introduced to increase population density or trophy ‘quality’. In Spain, red deer (Cervus elaphus) from different European subspecies have been introduced to increase the size of trophies (antlers) of local populations. Legislation against these introductions is not effective for various reasons, and once the individuals are in the Iberian peninsula it is virtually impossible to prevent their spreading throughout the whole territory without a genetic tool to distinguish between autochthonous and foreign specimens. We have developed such a genetic test and propose a strategy to dissuade land-owners from importing foreign deer. Since deer are bred mainly for their antlers, our strategy is based on an agreement with the National Trophy Body in Spain which rejects trophies from foreign populations. Rejection decreases the value of the trophy so that it becomes more profitable to produce autochthonous deer. Using such a strategy at some critical step in the production or commercialisation process may be a good model to apply in protecting genetic properties of exploited species

Influence of Green Versus Conventional Colored Buns on the Perceived Healthiness of Banana Heart Burgers Among Grades Four to Six Students at La Salle College Antipolo

This study investigated the influence of bun color on the perceived healthiness of banana heart burgers among grades four to six students at La Salle College Antipolo. Employing a quantitative experimental design, 30 participants were exposed to burgers with either green or conventional-colored buns. Data gathered through a structured survey were analyzed using frequency distributions and an Independent Samples T-Test. Results indicated that while the color green was overwhelmingly associated with healthiness (93.3%), changes in bun color did not significantly influence the perceived healthiness of the burgers (p = 0.784). Consequently, the study supports the null hypothesis, suggesting that visual cues such as bun color have minimal impact on the healthiness perception of food among children, underscoring the complexity of factors that influence dietary choices

Influence of Structural Defects on the Properties of Metamagnetic Shape Memory Alloys

The production of μ-particles of Metamagnetic Shape Memory Alloys by crushing and subsequent ball milling process has been analyzed. The high energy involved in the milling process induces large internal stresses and high density of defects with a strong influence on the martensitic transformation; the interphase creation and its movement during the martensitic transformation produces frictional contributions to the entropy change (exothermic process) both during forward and reverse transformation. The frictional contribution increases with the milling time as a consequence of the interaction between defects and interphases. The influence of the frictional terms on the magnetocaloric effect has been evidenced. Besides, the presence of antiphase boundaries linked to superdislocations helps to understand the spin-glass behavior at low temperatures in martensite. Finally, the particles in the deformed state were introduced in a photosensitive polymer. The mechanical damping associated to the Martensitic Transformation (MT) of the particles is clearly distinguished in the produced composite, which could be interesting for the development of magnetically-tunable mechanical dampers.This research was funded by Projects RTI2018-094683-B-C5 (4,5) (MCIU/AEI/FEDER,UE); ASACTEI Pcia.Santa Fe IO-2017-00138, PID-UNR ING 575 and ING 612 (2018–202

Health systems strengthening through surgical and perioperative care pathways- a changing paradigm

Global health has traditionally focused on the primary health development with disease-specific focus such as HIV, malaria and non-communicable diseases (NCDs). As such, surgery has traditionally been neglected in global health as investment in them is often expensive, relative to these other priorities. Therefore, efforts to improve surgical care have remained on the periphery of initiatives in health system strengthening. However, today, many would argue that global health should focus on universal health coverage with primary health and surgery and perioperative care integrated as a part of this. In this article, we discuss the past developments and future-looking solutions on how surgery can contribute to the delivery of effective and equitable healthcare across the world. These include bidirectional integration of surgical and chronic disease pathways and better understanding financing initiatives. Specifically, we focus on access to safe elective and emergency surgery for NCDs and an integrated approach towards the rising multimorbidity from chronic disease in the population. Underpinning these, data-driven solutions from high-quality research from clinical trials and cohort studies through established surgical research networks are needed. Although challenges will remain around financing, we propose that development of surgical services will strengthen and improve performance of whole health systems and contribute to improvement in population health across the world