3D facial movement replication using digital video

The Philippines is one of the growing game development countries in the world. As of now the game titles that have been produced by local companies are less than a handful. Some of today\u27s games are becoming more and more realistic in terms of the look, the feel and the motion that is done by the characters within a game. Motion capture is one of the most optimal way of replicating movement for 3D movement. The research has devised a way to replicate, or at the very least approximate, the movements of human face in a given digital video to a 3D face model. The proponents have utilized image processing techniques for movement detection and XML scripting for movement encoding. As for the #D face renderer, the proponents have used the XFace Toolkit. The system posted an average correctness of 80.60% using frame per second comparison of the input video and 3D animation sequence output. The proponents also conducted a survey to reduce the subjectivity of the visual comparison, which in turn has an average of 77.06% confidence value

RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues

Somatic mosaicism in normal tissues Somatic cells can accumulate mutations over the course of an individual's lifetime. This generates cells that differ genetically at specific loci within the genome. To explore how this genetic diversity in individuals contributes to disease, Yizhak et al. developed a method to detect mutations from RNA sequencing data (see the Perspective by Tomasetti). Applying this method to Cancer Genome Atlas samples and normal samples from the Genotype-Tissue Expression (GTEx) project generated a tissue-specific study of mutation accumulation. Somatic mutations were detected in nearly all individuals and across many normal human tissues in genomic regions called cancer hotspots and in genes that play a role in cancer. Interestingly, the skin, lung, and esophagus exhibited the most mutations, suggesting that the environment generates many human mutations. Science , this issue p. eaaw0726 ; see also p. 938 </jats:p