836 research outputs found
Factors used in the detection of elder financial abuse: A judgement and decision-making study of social workers and their managers
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 Sage Publications Ltd.Factors social workers use in practice to detect elder financial abuse are currently unknown. A critical incident technique was applied within a judgement analysis approach to elicit cue use. Only three factors were key to decision-making: who raises concern, the elder’s mental capacity and the nature of the financial anomaly occurring.Economic and Social Research Counci
Gas Accretion in Star-Forming Galaxies
Cold-mode gas accretion onto galaxies is a direct prediction of LCDM
simulations and provides galaxies with fuel that allows them to continue to
form stars over the lifetime of the Universe. Given its dramatic influence on a
galaxy's gas reservoir, gas accretion has to be largely responsible for how
galaxies form and evolve. Therefore, given the importance of gas accretion, it
is necessary to observe and quantify how these gas flows affect galaxy
evolution. However, observational data have yet to conclusively show that gas
accretion ubiquitously occurs at any epoch. Directly detecting gas accretion is
a challenging endeavor and we now have obtained a significant amount of
observational evidence to support it. This chapter reviews the current
observational evidence of gas accretion onto star-forming galaxies.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics
and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by
Springer. This chapter includes 22 pages with 7 Figure
Transverse Sizes of CIV Absorption Systems Measured from Multiple QSO Sightlines
We present tomography of the circum-galactic metal distribution at redshift
1.7 to 4.5 derived from echellete spectroscopy of binary quasars. We find CIV
systems at similar redshifts in paired sightlines more often than expected for
sightline-independent redshifts. As the separation of the sightlines increases
from 36 kpc to 907 kpc, the amplitude of this clustering decreases. At the
largest separations, the CIV systems cluster similar to Lyman-break galaxies
(Adelberger et al. 2005a). The CIV systems are significantly less correlated
than these galaxies, however, at separations less than R_1 ~ 0.42 +/- 0.15 h-1
comoving Mpc. Measured in real space, i.e., transverse to the sightlines, this
length scale is significantly smaller than the break scale estimated from the
line-of-sight correlation function in redshift space (Scannapieco et al.
2006a). Using a simple model, we interpret the new real-space measurement as an
indication of the typical physical size of enriched regions. We adopt this size
for enriched regions and fit the redshift-space distortion in the line-of-sight
correlation function. The fitted velocity kick is consistent with the peculiar
velocity of galaxies as determined by the underlying mass distribution and
places an upper limit on the outflow (or inflow) speed of metals. The implied
time scale for dispersing metals is larger than the typical stellar ages of
Lyman-break galaxies (Shapley et al. 2001), and we argue that enrichment by
galaxies at z > 4.3 played a greater role in dispersing metals. To further
constrain the growth of enriched regions, we discuss empirical constraints on
the evolution of the CIV correlation function with cosmic time. This study
demonstrates the potential of tomography for measuring the metal enrichment
history of the circum-galactic medium.Comment: 22 pages, 15 figures, 1 tabl
Gas Accretion via Lyman Limit Systems
In cosmological simulations, a large fraction of the partial Lyman limit
systems (pLLSs; 16<log N(HI)<17.2) and LLSs (17.2log N(HI)<19) probes
large-scale flows in and out of galaxies through their circumgalactic medium
(CGM). The overall low metallicity of the cold gaseous streams feeding galaxies
seen in these simulations is the key to differentiating them from metal rich
gas that is either outflowing or being recycled. In recent years, several
groups have empirically determined an entirely new wealth of information on the
pLLSs and LLSs over a wide range of redshifts. A major focus of the recent
research has been to empirically determine the metallicity distribution of the
gas probed by pLLSs and LLSs in sizable and representative samples at both low
(z2) redshifts. Here I discuss unambiguous evidence for
metal-poor gas at all z probed by the pLLSs and LLSs. At z<1, all the pLLSs and
LLSs so far studied are located in the CGM of galaxies with projected distances
<100-200 kpc. Regardless of the exact origin of the low-metallicity pLLSs/LLSs,
there is a significant mass of cool, dense, low-metallicity gas in the CGM that
may be available as fuel for continuing star formation in galaxies over cosmic
time. As such, the metal-poor pLLSs and LLSs are currently among the best
observational evidence of cold, metal-poor gas accretion onto galaxies.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics
and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by
Springe
A translational framework for public health research
<p><b>Background</b></p>
<p>The paradigm of translational medicine that underpins frameworks such as the Cooksey report on the funding of health research does not adequately reflect the complex reality of the public health environment. We therefore outline a translational framework for public health research.</p>
<p><b>Discussion</b></p>
<p>Our framework redefines the objective of translation from that of institutionalising effective interventions to that of improving population health by influencing both individual and collective determinants of health. It incorporates epidemiological perspectives with those of the social sciences, recognising that many types of research may contribute to the shaping of policy, practice and future research. It also identifies a pivotal role for evidence synthesis and the importance of non-linear and intersectoral interfaces with the public realm.</p>
<p><b>Summary</b></p>
<p>We propose a research agenda to advance the field and argue that resources for 'applied' or 'translational' public health research should be deployed across the framework, not reserved for 'dissemination' or 'implementation'.</p>
Who needs what from a national health research system: Lessons from reforms to the English Department of Health's R&D system
This article has been made available through the Brunel Open Access Publishing Fund.Health research systems consist of diverse groups who have some role in health research, but the boundaries around such a system are not clear-cut. To explore what various stakeholders need we reviewed the literature including that on the history of English health R&D reforms, and we also applied some relevant conceptual frameworks.
We first describe the needs and capabilities of the main groups of stakeholders in health research systems, and explain key features of policymaking systems within which these stakeholders operate in the UK. The five groups are policymakers (and health care managers), health professionals, patients and the general public, industry, and researchers. As individuals and as organisations they have a range of needs from the health research system, but should also develop specific capabilities in order to contribute effectively to the system and benefit from it.
Second, we discuss key phases of reform in the development of the English health research system over four decades -
especially that of the English Department of Health's R&D system - and identify how far legitimate demands of key stakeholder interests were addressed.
Third, in drawing lessons we highlight points emerging from contemporary reports, but also attempt to identify issues through application of relevant conceptual frameworks. The main lessons are: the importance of comprehensively addressing the diverse needs of various interacting institutions and stakeholders; the desirability of developing facilitating mechanisms at interfaces between the health research system and its various stakeholders; and the importance of additional money in being able to expand the scope of the health research system whilst maintaining support for basic science.
We conclude that the latest health R&D strategy in England builds on recent progress and tackles acknowledged weaknesses. The strategy goes a considerable way to identifying and more effectively meeting the needs of key groups such as medical academics, patients and industry, and has been remarkably successful in increasing the funding for health research. There are still areas that might benefit from further recognition and resourcing, but the lessons identified, and progress made by the reforms are relevant for the design and coordination of national health research systems beyond England.This article is available through the Brunel Open Access Publishing Fund
Tracing the wider impacts of biomedical research: A literature search to develop a novel citation categorisation technique
There is an increasing need both to understand the translation of biomedical research into improved healthcare and to assess the range of wider impacts from health research such as improved health policies, health practices and healthcare. Conducting such assessments is complex and new methods are being sought. Our new approach involves several steps. First, we developed a qualitative citation analysis technique to apply to biomedical research in order to assess the contribution that individual papers made to further research. Second, using this method, we then proposed to trace the citations to the original research through a series of generations of citing papers. Third, we aimed eventually to assess the wider impacts of the various generations. This article describes our comprehensive literature search to inform the new technique. We searched various databases, specific bibliometrics journals and the bibliographies of key papers. After excluding irrelevant papers we reviewed those remaining for either general or specific details that could inform development of our new technique. Various characteristics of citations were identified that had been found to predict their importance to the citing paper including the citation’s location; number of citation occasions and whether the author(s) of the cited paper were named within the citing paper. We combined these objective characteristics with subjective approaches also identified from the literature search to develop a citation categorisation technique that would allow us to achieve the first of the steps above, i.e., being able routinely to assess the contribution that individual papers make to further research.Medical Research Council as part of the MRC-NIHR Methodology Research Programme, and Professor Martin Buxton
Extremely metal-poor gas at a redshift of 7
In typical astrophysical environments, the abundance of heavy elements ranges from 0.001 to 2 times the solar value. Lower abundances have been seen in selected stars in the Milky Way’s halo and in two quasar absorption systems at redshift z = 3 (ref. 4). These are widely interpreted as relics from the early Universe, when all gas possessed a primordial chemistry. Before now there have been no direct abundance measurements from the first billion years after the Big Bang, when the earliest stars began synthesizing elements. Here we report observations of hydrogen and heavy-element absorption in a spectrum of a quasar at z = 7.04, when the Universe was just 772 million years old (5.6 per cent of its present age). We detect a large column of neutral hydrogen but no corresponding metals (defined as elements heavier than helium), limiting the chemical abundance to less than 1/10,000 times the solar level if the gas is in a gravitationally bound proto-galaxy, or to less than 1/1,000 times the solar value if it is diffuse and unbound. If the absorption is truly intergalactic, it would imply that the Universe was neither ionized by starlight nor chemically enriched in this neighbourhood at z ≈ 7. If it is gravitationally bound, the inferred abundance is too low to promote efficient cooling, and the system would be a viable site to form the predicted but as yet unobserved massive population III stars
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