Pre-main sequence stars with disks in the Eagle Nebula observed in scattered light

NGC6611 and its parental cloud, the Eagle Nebula (M16), are well-studied star-forming regions, thanks to their large content of both OB stars and stars with disks and the observed ongoing star formation. We identified 834 disk-bearing stars associated with the cloud, after detecting their excesses in NIR bands from J band to 8.0 micron. In this paper, we study in detail the nature of a subsample of disk-bearing stars that show peculiar characteristics. They appear older than the other members in the V vs. V-I diagram, and/or they have one or more IRAC colors at pure photospheric values, despite showing NIR excesses, when optical and infrared colors are compared. We confirm the membership of these stars to M16 by a spectroscopic analysis. The physical properties of these stars with disks are studied by comparing their spectral energy distributions (SEDs) with the SEDs predicted by models of T-Tauri stars with disks and envelopes. We show that the age of these stars estimated from the V vs. V-I diagram is unreliable since their V-I colors are altered by the light scattered by the disk into the line of sight. Only in a few cases their SEDs are compatible with models with excesses in V band caused by optical veiling. Candidate members with disks and photospheric IRAC colors are selected by the used NIR disk diagnostic, which is sensitive to moderate excesses, such as those produced by disks with low masses. In 1/3 of these cases, scattering of stellar flux by the disks can also be invoked. The photospheric light scattered by the disk grains into the line of sight can affect the derivation of physical parameters of ClassII stars from photometric optical and NIR data. Besides, the disks diagnostic we defined are useful for selecting stars with disks, even those with moderate excesses or whose optical colors are altered by veiling or photospheric scattered light.Comment: Accepted for publication in A&

The circumstellar disc around the Herbig AeBe star HD169142

We present 7 mm and 3.5 cm wavelength continuum observations toward the Herbig AeBe star HD169142 performed with the Very Large Array (VLA) with an angular resolution of ~1". We find that this object exhibits strong (~4.4 mJy), unresolved (~1") 7 mm continuum emission, being one of the brightest isolated Herbig AeBe stars ever detected with the VLA at this wavelength. No emission is detected at 3.5 cm continuum, with a 3 sigma upper limit of ~0.08 mJy. From these values, we obtain a spectral index of ~2.5 in the 3.5 cm to 7 mm wavelength range, indicating that the observed flux density at 7mm is most likely dominated by thermal dust emission coming from a circumstellar disc. We use available photometric data from the literature to model the spectral energy distribution (SED) of this object from radio to near-ultraviolet frequencies. The observed SED can be understood in terms of an irradiated accretion disc with low mass accretion rate, 10^{-8} solar masses per year, surrounding a star with an age of ~10 Myr. We infer that the mass of the disc is ~0.04 solar masses, and is populated by dust grains that have grown to a maximum size of 1 mm everywhere, consistent with the lack of silicate emission at 10 microns. These features, as well as indications of settling in the wall at the dust destruction radius, led us to speculate the disc of HD169142 is in an advanced stage of dust evolution, particularly in its inner regions.Comment: 13 pages, 2 figures. Accepted by MNRA

Correlation between the spatial distribution of circumstellar disks and massive stars in the young open cluster NGC 6611. II: Cluster members selected with Spitzer/IRAC

Context: the observations of the proplyds in the Orion Nebula Cluster, showing clear evidence of ongoing photoevaporation, have provided a clear proof about the role of the externally induced photoevaporation in the evolution of circumstellar disks. NGC 6611 is an open cluster suitable to study disk photoevaporation, thanks to its large population of massive members and of stars with disk. In a previous work, we obtained evidence of the influence of the strong UV field generated by the massive cluster members on the evolution of disks around low-mass Pre-Main Sequence members. That work was based on a multi-band BVIJHK and X-ray catalog purposely compiled to select the cluster members with and without disk. Aims: in this paper we complete the list of candidate cluster members, using data at longer wavelengths obtained with Spitzer/IRAC, and we revisit the issue of the effects of UV radiation on the evolution of disks in NGC 6611. Methods: we select the candidate members with disks of NGC 6611, in a field of view of 33'x34' centered on the cluster, using IRAC color-color diagrams and suitable reddening-free color indices. Besides, using the X-ray data to select Class III cluster members, we estimate the disks frequency vs. the intensity of the incident radiation emitted by massive members. Results: we identify 458 candidate members with circumstellar disks, among which 146 had not been revealed in our previous work. Comparing of the various color indices we used to select the cluster members with disk, we claim that they detect the excesses due to the emission of the same physical region of the disk: the inner rim at the dust sublimation radius. Our new results confirm that UV radiation from massive stars affects the evolution of nearby circumstellar disks.Comment: Accepted for publication at Astronomy & Astrophysic

Multiplicity, Disks and Jets in the NGC 2071 Star-Forming Region

We present centimeter and millimeter observations of the NGC 2071 star-forming region performed with the VLA and CARMA. We detected counterparts at 3.6 cm and 3 mm for the previously known sources IRS 1, IRS 2, IRS 3, and VLA 1. All these sources show SEDs dominated by free-free thermal emission at cm wavelengths, and thermal dust emission at mm wavelengths, suggesting that all of them are associated with YSOs. IRS 1 shows a complex morphology at 3.6 cm, with changes in the direction of its elongation. We discuss two possible explanations to this morphology: the result of changes in the direction of a jet due to interactions with a dense ambient medium, or that we are actually observing the superposition of two jets arising from two components of a binary system. Higher angular resolution observations at 1.3 cm support the second possibility, since a double source is inferred at this wavelength. IRS 3 shows a clear jet-like morphology at 3.6 cm. Over a time-span of four years, we observed changes in the morphology of this source that we interpret as due to ejection of ionized material in a jet. The emission at 3 mm of IRS 3 is angularly resolved, with a deconvolved size (FWHM) of ~120 AU, and seems to be tracing a dusty circumstellar disk perpendicular to the radio jet. An irradiated accretion disk model around an intermediate-mass YSO can account for the observed SED and spatial intensity profile at 3 mm, supporting this interpretation.Comment: Accepted by The Astrophysical Journa

Vertical structure models of T Tauri and Herbig Ae/Be disks

In this paper we present detailed models of the vertical structure (temperature and density) of passive irradiated circumstellar disks around T Tauri and Herbig Ae/Be stars. In contrast to earlier work, we use full frequency- and angle-dependent radiative transfer instead of the usual moment equations. We find that this improvement of the radiative transfer has strong influence on the resulting vertical structure of the disk, with differences in temperature as large as 70 %. However, the spectral energy distribution (SED) is only mildly affected by this change. In fact, the SED compares reasonably well with that of improved versions of the Chiang & Goldreich (CG) model. This shows that the latter is a reasonable model for the SED, in spite of its simplicity. It also shows that from the SED alone, little can be learned about the vertical structure of a passive circumstellar disk. The molecular line emission from these disks is more sensitive to the vertical temperature and density structure, and we show as an example how the intensity and profiles of various CO lines depend on the adopted disk model. The models presented in this paper can also serve as the basis of theoretical studies of e.g. dust coagulation and settling in disks.Comment: 12 pages, 15 figures, accepted for publication in A&

Molecular Detection of Babesia spp. (Apicomplexa: Piroplasma) in Free-Ranging Canids and Mustelids From Southern Italy.

Babesiosis is an emerging tick-borne disease caused by apicomplexan parasites with widespread geographical distribution and various wildlife species as reservoir hosts. The aims of this study were to investigate the prevalence and assess the role of free-ranging canids and mustelids in the maintenance of Babesia spp. in southern Italy. PCR analysis of splenic samples targeting the 18S rRNA gene revealed the presence of Babesia spp. in 36 of 82 (43.9%) red foxes (Vulpes vulpes) including 29 (58%) from Campania region and seven (21.8%) from Calabria region, in seven of 13 (53.8%) Eurasian badgers (Meles meles), and in one of 13 (7.7%) gray wolves (Canis lupus). Samples from other host species including 9 Eurasian otters (Lutra lutra), 1 stone marten (Martes foina), 1 least weasel (Mustela nivalis), and 1 European polecat (Mustela putorius) tested Babesia spp. negative. Sequence analysis of the 18S rRNA gene demonstrated the presence of B. vulpes in the red fox and two sequence types of badger-associated Babesia spp. in the Eurasian badger. The Babesia sp. sequence detected in the gray wolf was identical to a badger-associated Babesia sp. This study shows that the number of Babesia spp. infecting free-ranging carnivores in Italy is higher than currently believed, and suggests that these hosts may play an important role in the maintenance of the sylvatic cycle of these parasites. It is the first report of badger-associated Babesia spp. in Italy and in a gray wolf

The infrared properties of the new outburst star IRAS 05436-0007 in quiescent phase

We compiled and investigated the infrared/sub-mm/mm SED of the new outburst star IRAS 05436-0007 in quiescent phase. The star is a flat-spectrum source, with an estimated total luminosity of L_bol ~ 5.6 L_sun, typical of low-mass T Tauri stars. The derived circumstellar mass of 0.5 M_sun is rather high among low-mass YSOs. The observed SED differs from the SEDs of typical T Tauri stars and of 4 well-known EXors, and resembles more the SEDs of FU Orionis objects indicating the presence of a circumstellar envelope. IRAS 05436-0007 seems to be a Class II source with an age of approximately 4x10^5 yr. In this evolutionary stage an accretion disk is already fully developed, though a circumstellar envelope may also be present. Observations of the present outburst will provide additional knowledge on the source.Comment: 4 pages, 4 figures, to be published in Astronomy & Astrophysics Letter

Biological properties of a human compact anti-ErbB2 antibody.

ErbB2 is a prognostic factor and target of therapy for many carcinomas. In contrast with the other ErbB receptors, ErbB2 lacks a soluble direct ligand, but it is the preferred co-receptor for the ErbB family members, forming heterodimers with more potent and prolonged signalling activity than that of homodimers. We recently produced a new anti-ErbB2 antibody, Erb-hcAb, by fusion of Erbicin, a human, anti-ErbB2 scFv, selectively cytotoxic to ErbB2-positive cells, and a human Fc domain. This fully human antitumour antibody represents a compact version of an IgG1, with the cytotoxicity of the scFv moiety on target cells, combined with the ability of the Fc moiety to induce both antibody- and complement-dependent cytotoxicity. Here, we describe the main properties of Erb-hcAb, using as a reference Herceptin, an anti-ErbB2 humanized monoclonal currently employed in clinical immunotherapy. We found that both bivalent Erb-hcAb and Herceptin increase receptor phosphorylation and downregulation, whereas monovalent Erbicin does not. These results correlate with the finding that Erb-hcAb is capable of inducing apoptosis and inhibiting cell cycle progression in ErbB2-positive cells. Its powerful in vitro antitumour action matched that observed in vivo in experiments with human ErbB2-positive tumour xenografts established in athymic mice. Finally, Erb-hcAb displays a glycosylation profile virtually superimposable to that of a human IgG. These findings suggest that Erb-hcAb is a very promising new agent for the immunotherapy of carcinomas that overexpress the ErbB2 receptor

Discovery of a Planetary-Mass Brown Dwarf with a Circumstellar Disk

Using the Hubble Space Telescope, the 4 m Blanco telescope at the Cerro Tololo Inter-American Observatory, and the Spitzer Space Telescope, we have performed deep imaging from 0.8 to 8 um of the southern subcluster in the Chamaeleon I star-forming region. In these data, we have discovered an object, Cha 110913-773444, whose colors and magnitudes are indicative of a very low-mass brown dwarf with a circumstellar disk. In a near-infrared spectrum of this source obtained with the Gemini Near-Infrared Spectrograph, the presence of strong steam absorption confirms its late-type nature (>=M9.5) while the shapes of the H- and K-band continua and the strengths of the Na I and K I lines demonstrate that it is a young, pre-main-sequence object rather than a field dwarf. A comparison of the bolometric luminosity of Cha 110913-773444 to the luminosities predicted by the evolutionary models of Chabrier and Baraffe and Burrows and coworkers indicates a mass of 8+7/-3 M_Jup, placing it fully within the mass range observed for extrasolar planetary companions (M<=15 M_Jup). The spectral energy distribution of this object exhibits mid-infrared excess emission at >5 um, which we have successfully modeled in terms of an irradiated viscous accretion disk with M'<=10e-12 M_sun/year. Cha 110913-773444 is now the least massive brown dwarf observed to have a circumstellar disk, and indeed is one of the least massive free-floating objects found to date. These results demonstrate that the raw materials for planet formation exist around free-floating planetary-mass bodies.Comment: 5 pages, accepted to Astrophysical Journal Letter