Effect of a high forage: Concentrate ratio on milk yield, blood parameters and oxidative status in lactating cows

A feeding strategy that requires a forage: concentrate ratio equal to 70: 30, with at least five different herbs in the forage and the use of silages prohibited, has recently been introduced in Italy. Despite the benefits in terms of human health (lower ω6: ω3 ratio, higher conjugated linoleic acid level) of the obtained milk, little information regarding the possible effects on cows' health is available. The aim of this study was to evaluate the effects of such a feeding strategy in dairy cows (90 days in milk at the beginning of the trial) on milk yield and composition, and blood metabolic profile, including the evaluation of oxidative stress. The proposed feeding strategy, compared with a semi-intensive strategy, resulted in an improvement of animal oxidative status (lower levels of reactive oxygen metabolites, higher levels of antioxidant potential and anti-reactive oxygen metabolites) and a significant increase of milk urea only in the first part of the trial. No differences in milk yield and composition were detected throughout the trial

Black hole production in tachyonic preheating

We present fully non-linear simulations of a self-interacting scalar field in the early universe undergoing tachyonic preheating. We find that density perturbations on sub-horizon scales which are amplified by tachyonic instability maintain long range correlations even during the succeeding parametric resonance, in contrast to the standard models of preheating dominated by parametric resonance. As a result the final spectrum exhibits memory and is not universal in shape. We find that throughout the subsequent era of parametric resonance the equation of state of the universe is almost dust-like, hence the Jeans wavelength is much smaller than the horizon scale. If our 2D simulations are accurate reflections of the situation in 3D, then there are wide regions of parameter space ruled out by over-production of black holes. It is likely however that realistic parameter values, consistent with COBE/WMAP normalisation, are safetly outside this black hole over-production region.Comment: 6pages, 7figures, figures correcte

Nutritional management of search and rescue dogs

Dogs used for search and rescue (SAR) may experience continuous micro-traumas that predispose them to skeletal disorders. The aim of the present study was to evaluate the effect of diet on osteo-articular apparatus in healthy SAR dogs. A total of sixteen SAR dogs were divided into two groups (low supplementation (LS) and high supplementation (HS)) and were fed for 3 months with two experimental diets, characterised by the same protein and energy density, but different inn-3 PUFA (6·2v. 8·4 % of metabolisable energy), chondroitin sulfate (219·8v. 989·0 mg/kg DM) and glucosamine (769·2v. 1318·7 mg/kg DM) in the LS and HS groups, respectively. At recruitment all dogs showed no joint inflammation signs, except four that showed mild symptoms. Haematology and serum biochemistry were performed every 30 d. Joint status was scored by physical and lameness evaluations. The sampling effect analysis showed potential beneficial effects by a decrease in a specific marker of membrane integrity (creatine kinase; CK). Comparing groups, glucose was significantly higher and CK was significantly lower in the HS group; however, in both cases the levels of these parameters fell in the normal range. At the end of the experiment, erythrocytes, Hb and packed cell volume were significantly higher in the HS compared with the LS group. These could result in an improvement in dogs' performance, even if this aspect was not investigated in the present study. Concerning joint evaluation (pain on manipulation, lameness and range of motion), no statistically significant differences were detected between the groups and within the experimental period

Mirrors Improve Rabbit Natural Behavior in a Free-Range Breeding System

The aim of this research was to evaluate the possible usefulness of mirrors in improving rabbit behavior in a free-range breeding system. Three groups (each consisting of nine replicates of three animals) were compared: isolated, isolated with mirrors and separated by a wire mesh (possible visual and olfactory contacts). Rabbits allowed to have a visual and olfactory contact showed a significantly higher expression of important natural behaviors (olfactory investigation, gnawing, alertness, stretching, locomotion) compared to the isolated rabbits (with or without mirrors); while rabbits in the mirror group showed higher allo-grooming activity than those isolated and no different locomotion activity than those separated by wire mesh. Thus, mirrors seemed to be able to modify the behavioral repertoire of isolated rabbits by acting on social perception in rabbits reared in small groups in a free-range system. Nevertheless, despite it being advisable to use a combination of different indicators in order to assess the stress level of an animal, the accuracy of serum cortisol, as well as of some secondary stress markers assay, appeared to be limited in this type of breeding

Influence of dietary hydrogenated palm oil supplementation on serum biochemistry and progesterone levels in dairy goats

The aim of this research was to investigate the influence of hydrogenated palm oil (HPO) added to a dairy goat diet on serum biochemistry and progesterone levels. Thirty pregnant Cilentana dairy goats were equally divided into 2 groups (control [CTR] and HPO groups). After kidding, concentrated feed for both groups was gradually increased up to 400 g/(animal$d), and the HPO group received 50 g/(animal$d) of HPO. Supplementation with HPO significantly increased cholesterol levels (mg/dL, 63.80 vs. 54.68 at 30 d, P 0.05; 78.20 vs. 58.00 at 60 d, P 0.05; 83.80 vs. 57.83 at 120 d, P 0.01) compared with the CTR group although no significant differences were detected for liver and kidney function indicators. Moreover, other biochemical parameters were not affected by HPO supplementation thus suggesting no change occurred in lipid and protein metabolism. Furthermore, a significant correlation was found be- tween progesterone levels and serum cholesterol (r 1⁄4 0.65, P 0.01) although these were not signifi- cantly higher in HPO supplemented goats. The dose and time of HPO supplementation appears critical as regards assessing the limits between the risks and benefits of HPO supplementation in dairy goats. At the tested dose, HPO was well tolerated by the animals and may represent a useful tool to increase energy availability during highly demanding periods

Effects of a nutritional supplement in dogs affected by osteoarthritis

Osteoarthritis is a form of chronic joint inflammation caused by the deterioration of the joint cartilage, accompanied by chronic pain, lameness and stiffness, particularly after prolonged activity. Alternative treatments of canine osteoarthritis would be desirable and, recently nutraceuticals, have been proposed for this purpose. Twenty cross breed adult dogs affected by osteoarthritis were enrolled and equally divided into two groups (control vs. experimental). The nutritional supplement (Dynamopet srl, Verone, Italy) was administered for 90 days to the dogs of the experimental group in order to evaluate its metabolic and locomotor effects. All the clinical signs (lameness, pain on manipulation and palpation, range of motion and joint swelling) significantly (p < 0.01) improved during the trial as regards the experimental group. This group showed a significantly lower joint score than the control group (mean value 7.40 vs. 3.80). With regard to haematology, the mean corpuscular volume resulted significantly (p < 0.01) higher in the experimental group, i.e. alkaline phosphatase, cholesterol and triglycerides values decreased and were significantly (p < 0.01) lower than the control one, thus suggesting an improvement in bone remodelling and lipid metabolism. A decrease in the reactive oxygen metabolites and an increase in the biological antioxidant potential demonstrated an improvement in oxidative stress during the trial in the experimental group compare to the control group. Interleukins 6 decreased in the experimental group, while interleukins 10 resulted in the opposite trend. Moreover, the administration of up to 3 months of the studied supplement was well tolerated in the dogs and caused no adverse effects

circular urban metabolism framework

In our cities, the production and consumption of resources are achieved at an unsustainable rate. Combined with an increasing global population and accelerating urbanization, the absence of a new approach will almost certainly have dramatic environmental consequences. Potential solutions are emerging: the concepts of circular economy (CE) and urban metabolism (UM), which contrast the current and traditional linear extract-produce-use-dispose model of the modern economic and urban systems, offer a new approach. In this Primer, we present the principles of CE and UM as well as their origins and definitions, strengths and weaknesses, similarities, and limits. We introduce how these concepts can be used for designing a new urban framework called circular urban metabolism (CUM), which encourages urban planners and decision makers to study, design, and manage sustainable cities. CUM has the potential to unite research fields to promote collaboration across disciplines that operate on the planning, design, and management of cities and their complexities