Gingival crevicular fluid alkaline phosphatase activity in relation to pubertal growth spurt and dental maturation: A multiple regression study

Introduction: The identification of the onset of the pubertal growth spurt has major clinical implications when dealing with orthodontic treatment in growing subjects. Aim: Through multivariate methods, this study evaluated possible relationships between the gingival crevicular fluid (GCF) alkaline phosphatase (ALP) activity and pubertal growth spurt and dentition phase. Materials and methods: One hundred healthy growing subjects (62 females, 38 males; mean age, 11.5±2.4 years) were enrolled into this doubleblind, prospective, cross-sectional-design study. Phases of skeletal maturation (pre - pubertal, pubertal, post - pubertal) was assessed using the cervical vertebral maturation method. Samples of GCF for the ALP activity determination were collected at the mesial and distal sites of the mandibular central incisors. The phases of the dentition were recorded as intermediate mixed, late mixed, or permanent. A multinomial multiple logistic regression model was used to assess relationships of the enzymatic activity to growth phases and dentition phases. Results: The GCF ALP activity was greater in the pubertal growth phase as compared to the pre - pubertal and post - pubertal growth phases. Significant adjusted odds ratios for the GCF ALP activity for the pre - pubertal and post - pubertal subjects, in relation to the pubertal group, were 0.76 and 0.84, respectively. No significant correlations were seen for the dentition phase. Conclusions: The GCF ALP activity is a valid candidate as a non - invasive biomarker for the identification of the pubertal growth spurt irrespective of the dentition phase

On the Origin of the Type Ia Supernova Width-Luminosity Relation

Brighter Type Ia supernovae (SNe Ia) have broader, more slowly declining B-band light curves than dimmer SNe Ia. We study the physical origin of this width-luminosity relation (WLR) using detailed radiative transfer calculations of Chandrasekhar mass SN Ia models. We find that the luminosity dependence of the diffusion time (emphasized in previous studies) is in fact of secondary relevance in understanding the model WLR. Instead, the essential physics involves the luminosity dependence of the spectroscopic/color evolution of SNe Ia. Following maximum-light, the SN colors are increasingly affected by the development of numerous Fe II/Co II lines which blanket the B-band and, at the same time, increase the emissivity at longer wavelengths. Because dimmer SNe Ia are generally cooler, they experience an earlier onset of Fe III to Fe II recombination in the iron-group rich layers of ejecta, resulting in a more rapid evolution of the SN colors to the red. The faster B-band decline rate of dimmer SNe Ia thus reflects their faster ionization evolution.Comment: 6 pages, submitted to Ap

The Persistence of Memory, or How the X-Ray Spectrum of SNR 0509-67.5 Reveals the Brightness of its Parent Type Ia Supernova

We examine the dynamics and X-ray spectrum of the young Type Ia supernova remnant 0509-67.5 in the context of the recent results obtained from the optical spectroscopy of its light echo. Our goal is to estimate the kinetic energy of the supernova explosion using Chandra and XMM-Newton observations of the supernova remnant, thus placing the birth event of 0509-67.5 in the sequence of dim to bright Type Ia supernovae. We base our analysis on a standard grid of one-dimensional delayed detonation explosion models, together with hydrodynamic and X-ray spectral calculations of the supernova remnant evolution. From the remnant dynamics and the properties of the O, Si, S, and Fe emission in its X-ray spectrum we conclude that 0509-67.5 was originated ~400 years ago by a bright, highly energetic Type Ia explosion similar to SN 1991T. Our best model has a kinetic energy of 1.4x10E51 erg and synthesizes 0.97 Msun of 56Ni. These results are in excellent agreement with the age estimate and spectroscopy from the light echo. We have thus established the first connection between a Type Ia supernova and its supernova remnant based on a detailed quantitative analysis of both objects.Comment: 10 pages, 9 figures, plus an exclusive astro-ph-only Appendix; ApJ in press, companion paper to Rest et al. 0

Diversity of Decline-Rate-Corrected Type Ia Supernova Rise Times: One Mode or Two?

B-band light-curve rise times for eight unusually well-observed nearby Type Ia supernovae (SNe) are fitted by a newly developed template-building algorithm, using light-curve functions that are smooth, flexible, and free of potential bias from externally derived templates and other prior assumptions. From the available literature, photometric BVRI data collected over many months, including the earliest points, are reconciled, combined, and fitted to a unique time of explosion for each SN. On average, after they are corrected for light-curve decline rate, three SNe rise in 18.81 +- 0.36 days, while five SNe rise in 16.64 +- 0.21 days. If all eight SNe are sampled from a single parent population (a hypothesis not favored by statistical tests), the rms intrinsic scatter of the decline-rate-corrected SN rise time is 0.96 +0.52 -0.25 days -- a first measurement of this dispersion. The corresponding global mean rise time is 17.44 +- 0.39 days, where the uncertainty is dominated by intrinsic variance. This value is ~2 days shorter than two published averages that nominally are twice as precise, though also based on small samples. When comparing high-z to low-z SN luminosities for determining cosmological parameters, bias can be introduced by use of a light-curve template with an unrealistic rise time. If the period over which light curves are sampled depends on z in a manner typical of current search and measurement strategies, a two-day discrepancy in template rise time can bias the luminosity comparison by ~0.03 magnitudes.Comment: As accepted by The Astrophysical Journal; 15 pages, 6 figures, 2 tables. Explanatory material rearranged and enhanced; Fig. 4 reformatte

Can differences in the nickel abundance in Chandrasekhar mass models explain the relation between brightness and decline rate of normal Type Ia Supernovae?

The use of Type Ia supernovae as distance indicators relies on the determination of their brightness. This is not constant, but it can be calibrated using an observed relation between the brightness and the properties of the optical light curve (decline rate, width, shape), which indicates that brighter SNe have broader, slower light curves. However, the physical basis for this relation is not yet fully understood. Among possible causes are different masses of the progenitor white dwarfs or different opacities in Chandrasekhar-mass explosions. We parametrise the Chandrasekhar-mass models presented by Iwamoto et al (1999), which synthesize different amounts of Ni, and compute bolometric light curves and spectra at various epochs. Since opacity in SNe Ia is due mostly to spectral lines, it should depend on the mass of Fe-peak elements synthesized in the explosion, and on the temperature in the ejecta. Bolometric light curves computed using these prescriptions for the optical opacity reproduce the relation between brightness and decline rate. Furthermore, when spectra are calculated, the change in colour between maximum and two weeks later allows the observed relation between M_B(Max) and Dm_{15}(B) to be reproduced quite nicely. Spectra computed at various epochs compare well with corresponding spectra of spectroscopically normal SNeIa selected to cover a similar range of Dm_{15}(B) values.Comment: 25 pages, including 6 figures. Accepted for publication in Ap

On Variations in the Peak Luminosity of Type Ia Supernovae

We explore the idea that the observed variations in the peak luminosities of Type Ia supernovae originate in part from a scatter in metallicity of the main-sequence stars that become white dwarfs. Previous, numerical, studies have not self-consistently explored metallicities greater than solar. One-dimensional Chandrasekhar mass models of SNe Ia produce most of their 56Ni in a burn to nuclear statistical equilibrium between the mass shells 0.2 and 0.8 solar masses, for which the electron to nucleon ratio is constant during the burn. We show analytically that, under these conditions, charge and mass conservation constrain the mass of 56Ni produced to depend linearly on the original metallicity of the white dwarf progenitor. Detailed post-processing of W7-like models confirms this linear dependence. The effect that we identify is most evident at metallicities larger than solar, and is in agreement with previous self-consistent calculations over the metallicity range common to both calculations. The observed scatter in the metallicity (1/3--3 times solar) of the solar neighborhood is enough to induce a 25% variation in the mass of 56Ni ejected by Type Ia supernovae. This is sufficient to vary the peak V-band brightness by approximately 0.2. This scatter in metallicity is present out to the limiting redshifts of current observations (z < 1). Sedimentation of 22Ne can possibly amplify the variation in 56Ni mass up to 50%. Further numerical studies can determine if other metallicity-induced effects, such as a change in the mass of the 56Ni-producing region, offset or enhance this variation.Comment: 4 pages, 1 figure, to appear in ApJL. Uses emulateapj.cls (included

Medium Modification of The Pion-Pion Interaction at Finite Density

We discuss medium modifications of the unitarized pion-pion interaction in the nuclear medium. We incorporate both the effects of chiral symmetry restoration and the influence of collective nuclear pionic modes originating from the p-wave coupling of the pion to delta-hole configurations. We show in particular that the dropping of the sigma meson mass significantly enhances the low energy structure created by the in-medium collective pionic modes.Comment: 26 pages, 7 figures included, Latex fil

Optical and Infrared Photometry of the Unusual Type Ia Supernova 2000cx

We present optical and infrared photometry of the unusual Type Ia supernova 2000cx. With the data of Li et al. (2001) and Jha (2002), this comprises the largest dataset ever assembled for a Type Ia SN, more than 600 points in UBVRIJHK. We confirm the finding of Li et al. regarding the unusually blue B-V colors as SN 2000cx entered the nebular phase. Its I-band secondary hump was extremely weak given its B-band decline rate. The V minus near infrared colors likewise do not match loci based on other slowly declining Type Ia SNe, though V-K is the least ``abnormal''. In several ways SN 2000cx resembles other slow decliners, given its B-band decline rate (Delta m_15(B) = 0.93), the appearance of Fe III lines and weakness of Si II in its pre-maximum spectrum, the V-K colors and post-maximum V-H colors. If the distance modulus derived from Surface Brightness Fluctuations of the host galaxy is correct, we find that the rate of light increase prior to maximum, the characteristics of the bolometric light curve, and the implied absolute magnitude at maximum are all consistent with a sub-luminous object with Delta m_15(B) ~ 1.6-1.7 having a higher than normal kinetic energy.Comment: 46 pages, 17 figures, to be published in Publications of the Astronomical Society of the Pacifi

On the fraction of intermediate-mass close binaries that explode as type-Ia supernovae

Type-Ia supernovae (SNe-Ia) are thought to result from a thermonuclear runaway in white dwarfs (WDs) that approach the Chandrasekhar limit, either through accretion from a companion or a merger with another WD. I compile observational estimates of the fraction eta of intermediate-mass stars that eventually explode as SNe-Ia, supplement them with several new estimates, and compare them self-consistently. The estimates are based on five different methods, each utilising some observable related to the SN-Ia rate, combined with assumptions regarding the IMF: the ratio of SN-Ia to core-collapse rates in star-forming galaxies; the SN-Ia rate per unit star-formation rate; the SN-Ia rate per unit stellar mass; the iron to stellar mass ratio in galaxy clusters; and the abundance ratios in galaxy clusters. The five methods indicate that a fraction in the range eta~2-40% of all stars with initial masses of 3-8 M_sun (the generally assumed SN-Ia progenitors) explode as SNe-Ia. A fraction of eta~15% is consistent with all five methods for a range of plausible IMFs. Considering also the binarity fraction among such stars, the mass ratio distribution, the separation distribution, and duplicity (every binary can produce only one SN-Ia explosion), this implies that nearly every intermediate mass close binary ends up as a SN-Ia, or possibly more SNe-Ia than progenitor systems. Theoretically expected fractions are generally one to two orders of magnitude lower. The problem could be solved: if all the observational estimates are in error; or with a ``middle-heavy'' IMF; or by some mechanism that strongly enhances the efficiency of binary evolution toward SN-Ia explosion; or by a non-binary origin for SNe-Ia.Comment: MNRAS, accepted versio