31 research outputs found
Adiponectin circulating levels and 10-year (2002–2012) cardiovascular disease incidence:the ATTICA Study
Purpose: Adiponectin is an adipokine with anti-inflammatory and cardiovascular-protective properties. Existing epidemiological evidence is conflicting on the exact relationship between adiponectin and long-term cardiovascular disease (CVD) risk. Our aim was to prospectively assess whether circulating adiponectin is associated with long-term incident CVD. Methods: A population-based, prospective study in adults (>18 years) without previous CVD history (ATTICA study). Circulating total adiponectin levels were measured at baseline (2001–2002) in a sub-sample (n = 531; women/men: 222/309; age: 40 ± 11 years) of the ATTICA cohort and complete 10-year follow-up data were available in 366 of these participants (women/men: 154/212; age: 40 ± 12 years). Results: After adjusting for multiple factors, including age, sex, body mass index, waist circumference, smoking, physical activity, Mediterranean diet adherence, hypertension, diabetes, and hypercholesterolemia, our logistic regression analysis indicates that an increase in circulating total adiponectin levels by 1 unit was associated with 36% lower CVD risk (relative risk [RR]: 0.64, 95% confidence interval [CI] 0.42–0.96; p = 0.03). Further adjusting for interleukin-6 plasma levels had no significant impact (RR: 0.60, 95% CI 0.38–0.94; p = 0.03), while additional adjustment for circulating C-reactive protein (CRP) modestly attenuated this association (RR: 0.63, 95% CI 0.40–0.99; p = 0.046). Conclusions: In our study, elevated circulating total adiponectin levels were associated with lower 10-year CVD risk in adults without previous CVD, independently of other established CVD risk factors. This association appeared to be modestly attenuated by CRP, yet was not mediated by interleukin-6 which is the main endocrine/circulating pro-inflammatory cytokine
Adiponectin and interleukin-6 levels in insulin-treated diabetic rats with experimental periodontitis
The psychology of passion: A meta-analytical review of a decade of research on intrapersonal outcomes
It is just over a decade since Vallerand et al. (J Personal Soc Psychol 85:756–767, 2003) introduced the dualistic model of passion. In this study, we conduct a meta-analytical review of relationships between Vallerand et al’s two passions (viz. harmonious and obsessive), and intrapersonal outcomes, and test the moderating role of age, gender, domain, and culture. A systematic literature search yielded 94 studies, within which 27 criterion variables were reported. These criterion variables derived from four research areas within the intrapersonal sphere: (a) well-/ill-being, (b) motivation factors, (c) cognitive outcomes and, (d) behaviour and performance. From these areas we retrieved 1308 independent effect sizes and analysed them using random-effects models. Results showed harmonious passion positively corresponded with positive intrapersonal outcomes (e.g., positive affect, flow, performance). Obsessive passion, conversely, showed positive associations with positive and negative
Perfectionism and emotion regulation in coaches: A test of the 2 × 2 model of dispositional perfectionism
The manner in which coaches regulate their emotions has implications for their performance and well-being. Drawing on research that has found perfectionism to predict emotion regulation in other settings, this study adopted the 2 × 2 model of perfectionism to examine whether subtypes of perfectionism among coaches were associated with variation in the use of emotion regulation strategies. Coaches (N = 238, M age = 23.92, SD = 10.32) from various sports completed measures of perfectionism (personal standards and evaluative concerns) and emotion regulation strategies (expressive suppression, cognitive reappraisal, and control of anger directed inwards and outwards). Moderated hierarchical regression provided mixed support for the 2 × 2 model. As expected, pure personal standards perfectionism (high standards/low concerns) was generally associated with the highest capacity for emotion regulation and pure evaluative concerns perfectionism (low standards/high concerns) with the lowest. Unexpectedly, mixed perfectionism (high standards/high concerns) was associated with the highest level of expressive suppression, suggesting that in some instances standards might exacerbate rather than attenuate concerns
