47 research outputs found
Enhanced recovery from growth inhibition in irradiated MO4 spheroids invading into embryonic chick heart fragments in organ cultures
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Recovery from growth inhibition in irradiated MO4 spheroids: suspension cultures versus explanted cultures
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Invasiveness and tumorigenicity of MO4 mouse fibrosarcoma cells pretreated with microtubule inhibitors.
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Vinblastine, Vincristine and Vindesine: antiinvasive effect on MO4 mouse fibrosarcoma cells in vitro.
No full textIntrinsic radiosensitivity of human pancreatic tumour cells and the radiosensitising potency of the nitric oxide donor sodium nitroprusside
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EVIDENCE FOR ABROGATION OF ONCOGENE-INDUCED RADIORESISTANCE OF MAMMARY-CANCER CELLS BY HEXADECYLPHOSPHOCHOLINE IN-VITRO.
No full textHexadecylphosphocholine (HePC), an experimental and clinical antitumour agent of the alkyllysophospholipid group, was tested for its radiosensitisting effect on a panel of nine human mammary cancer cell lines in vitro. Growth inhibition by ionising radiation and recovery from it were not influenced by pretreatment with HePC in most cases, except for two cell lines expressing an activated ras oncogene. In the latter we found an enhanced radioresistance that was abolished by pretreatment with HePC. Our results suggest that HePC may act as a radiosensitiser for cells carrying an activated ras oncogene. © 1993.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
