Commissioning strategies and methods

Accelerator beam commissioning is a challenging and exciting period. It is generally the first integrated operation of the many systems in an accelerator and, most importantly, of the beam. First, general preparation is discussed. Then general methods for initial beam commissioning are described, including methods for transverse and longitudinal beam set-up. The particular emphasis here is on tuning methods for linear accelerators.Comment: 16 pages, contribution to the CAS - CERN Accelerator School: Course on High Power Hadron Machines; 24 May - 2 Jun 2011, Bilbao, Spai

Electrophysiological studies of the nervous system

The electrophysiology of the nervous system is studied using cats and human subjects. Data cover effects of chlorolose on evoked potential, the evoked resistance shift that accompanies evoked potentials, and the relationship of eye movements to potentials aroused by visual stimulation

On hemispheric differences in evoked potentials to speech stimuli

Confirmation is provided for the belief that evoked potentials may reflect differences in hemispheric functioning that are marginal at best. Subjects were right-handed and audiologically normal men and women, and responses were recorded using standard EEG techniques. Subjects were instructed to listen for the targets while laying in a darkened sound booth. Different stimuli, speech and tone signals, were used. Speech sounds were shown to evoke a response pattern that resembles that to tone or clicks. Analysis of variances on peak amplitude and latency measures showed no significant differences between hemispheres, however, a Wilcoxon test showed significant differences in hemispheres for certain target tasks

Clinical applications of the human brainstem responses to auditory stimuli

A technique utilizing the frequency following response (FFR) (obtained by auditory stimulation, whereby the stimulus frequency and duration are mirror-imaged in the resulting brainwaves) as a clinical tool for hearing disorders in humans of all ages is presented. Various medical studies are discussed to support the clinical value of the technique. The discovery and origin of the FFR and another significant brainstem auditory response involved in studying the eighth nerve is also discussed

Summary of the Superconducting RF Linac for Muon Collider and Neutrino Factory

Project-X is a proposed project to be built at Fermi National Accelerator Laboratory with several potential missions. A primary part of the Project-X accelerator chain is a Superconducting linac, and In October 2009 a workshop was held to concentrate on the linac parameters. The charge of the workshop was to "..focus only on the SRF linac approaches and how it can be used...". The focus of Working Group 2 of this workshop was to evaluate how the different linac options being considered impact the potential realization of Muon Collider (MC) and Neutrino Factory (NF) applications. In particular the working group charge was, "to investigate the use of a multi-megawatt proton linac to target, phase rotate and collect muons to support a muon collider and neutrino factory". To focus the working group discussion, three primary questions were identified early on, to serve as a reference: 1) What are the proton source requirements for muon colliders and neutrino factories? 2) What are the issues with respect to realizing the required muon collider and neutrino factory proton sources? a. General considerations b. Considerations specific to the two linac configurations identified by Project-X. 3) What things need to be done before we can be reasonably confident that ICD1/ICD2 can be upgraded to provide the neutrino factory / muon collider needs? A number of presentations were given, and are available at the workshop web-site. This paper does not summarize the individual presentations, but rather addresses overall findings as related to the three guiding questions listed above.Comment: 6 pp. Workshop on Applications of High Intensity Proton Accelerators 19-21 Oct 2009: Batavia, Illinoi

Electrophysiological measurement of human auditory function

Knowledge of the human auditory evoked response is reviewed, including methods of determining this response, the way particular changes in the stimulus are coupled to specific changes in the response, and how the state of mind of the listener will influence the response. Important practical applications of this basic knowledge are discussed. Measurement of the brainstem evoked response, for instance, can state unequivocally how well the peripheral auditory apparatus functions. It might then be developed into a useful hearing test, especially for infants and preverbal or nonverbal children. Clinical applications of measuring the brain waves evoked 100 msec and later after the auditory stimulus are undetermined. These waves are clearly related to brain events associated with cognitive processing of acoustic signals, since their properties depend upon where the listener directs his attention and whether how long he expects the signal

Loudness enhancement: Monaural, binaural and dichotic

It is shown that when one tone burst precedes another by 100 msec variations in the intensity of the first systematically influences the loudness of second. When the first burst is more intense than the second, the second is increased and when the first burst is less intense, the loudness of the second is decreased. This occurs in monaural, binaural and dichotic paradigms of signal presentation. Where both bursts are presented to the same ear there is more enhancement with less intersubject variability than when they are presented to different ears. Monaural enhancements as large as 30 db can readily be demonstrated, but decrements rarely exceed 5 db. Possible physiological mechanisms are discussed for this loudness enhancement, which apparently shares certain characteristics with time-order-error, assimilation, and temporal partial masking experiments

Electrophysiological measurement of human auditory function

Contingent negative variations in the presence and amplitudes of brain potentials evoked by sound are considered. Evidence is produced that the evoked brain stem response to auditory stimuli is clearly related to brain events associated with cognitive processing of acoustic signals since their properties depend upon where the listener directs his attention, whether the signal is an expected event or a surprise, and when sound that is listened-for is heard at last

The capacitated transshipment location problem with stochastic handling utilities at the facilities

The problem consists in finding a transshipment facilities location that maximizes the total net utility when the handling utilities at the facilities are stochastic variables, under supply, demand, and lower and upper capacity constraints. The total net utility is given by the expected total shipping utility minus the total fixed cost of the located facilities. Shipping utilities are given by a deterministic utility for shipping freight from origins to destinations via transshipment facilities plus a stochastic handling utility at the facilities, whose probability distribution is unknown. After giving the stochastic model, by means of some results of the extreme values theory, the probability distribution of the maximum stochastic utilities is derived and the expected value of the optimum of the stochastic model is found. An efficient heuristics for solving real-life instances is also given. Computational results show a very good performance of the proposed methods both in terms of accuracy and efficienc