830 research outputs found
The Applicability of the Eclectic Method on the Development of the Oral Production
Developing our students\u27 English oral expression in Public Institutions is a process that needs to be carefully analyzed by teachers. It is more than selected a method, it is more than following step by step what a theory says. It is going beyond our students\u27 needs. It is a deeply study of what a student really can do and needs to learn. Based on a post-method pedagogy which provides teachers the ability to break down barriers to the imposition of a specific method and make the teaching process more effective, this paper proposes the application of the eclectic method for the development of the oral expression of public high school students encouraging teachers to see the teaching process from a different and modern perspective. By analyzing the principles and features of this method, this paper describes the research made on a Public Institution with students in third year. With the goal of improving each one of the principal components of the English oral expression: range, accuracy, fluency, pronunciation and coherence, there were used selected methods, techniques and strategies based upon the students\u27 learning styles and needs. The observation and Interview techniques were used on data collection and the parameters of Inferential and descriptive statistic were applied in order to analyze the results achieved. They showed that even though not all of the group of the students could achieve the B1 level in reference to the Common European Framework and required by the Ministry of Education, a large number of them were able to increase their English oral expression. According to this data, this paper concludes that the selection of objectives, the modern teacher‘s and student\u27s role, the use of different but selected methods, the linguistic input activation and the contextualization had a significant impact on learners´ learning
Prevalência de Doença Carotídea na Patologia Cérebro-Vascular Isquémica. O Papel do Eco-Doppler
BACKGROUND: Atherosclerotic carotid disease represents approximately 20% of the causes of ischemic stroke. Effective treatment options, such as endovascular or surgical revascularization procedures, are available. Doppler Ultrasound (DUS) is a non-invasive, inexpensive, routine exam used to evaluate the presence of internal carotid artery (ICA) stenosis. We retrospectively analysed the prevalence of severe atherosclerotic carotid disease in a population of patients with acute ischemic stroke/transitory ischemic attacks (TIAs), and the role of DUS in the detection of ICA stenosis and treatment decisions in these patients.
METHODS: A total of 318 patients with ischemic stroke or TIAs was admitted to our stroke unit, and 260 patients were studied by DUS. ICA stenosis was evaluated by DUS according to peak systolic velocity. All DUS exams were performed by the same operator. ICA stenosis was further assessed in 43 patients by digital subtraction angiography (DSA) using NASCET criteria.
RESULTS: Of the total 318 patients, 260 (82%) had DUS evaluation. Of the total 520 ICAs studied by DUS, degrees of ICA stenosis were: 0-29% n= 438 (84%); 30-49% n= 8 (2%); 50-69% n= 27 (5%); 70-89% n= 15 (3%); 90-99% n= 20 (4%); oclusão n= 14 (2%). Of the total 260 patients studied, 43 (16.5%) underwent DSA. Sensibility and specificity of DUS in the diagnosis of carotid stenosis over 70% were, respectively, 91% e 84%. Of the total 31 patients with significant carotid stenosis (70-99%), 23 (74%) underwent subsequent carotid revascularization procedures.
DISCUSSION: DUS is an important screening test in our stroke unit, justifying its use as a routine exam for all patients with ischemic stroke/TIAs. Moreover, our results show the relevance of severe carotid disease in a population with acute ischemic stroke/TIAs (16.5%), with a total of 9% of patients being submitted to carotid revascularization procedures
Photosensitivity Color-Center Model for Ge-Doped Silica Preforms
A new photosensitivity physical model for Ge-doped silica preforms based on
color-center photoreactions is presented. Simulation results are in close agreement with
experimental results obtained by several condensed matter physics research groups working
in this field, suggesting that the photoreactions of this model may, indeed, describe the
physical processes involved in Ge-doped silica preform photosensitivity. The proposed
photosensitivity model is defined by two differential equations that describe the temporal
evolution of a set of color-center concentrations. The first is a modification of a very fast
reversible reaction previously proposed by Fujimaki et al., where the reaction precursor has
a different chemical structure (it is a neutral oxygen divacancy NODV unrelated to the
previously proposed germanium lone pair center GLPC). The chemical structure of this
precursor defect explains the generation of nonintrinsic neutral oxygen monovacancy
ðNOMVÞ color centers. These centers are transformed into GeE0 defects by means of a
second nonlinear reaction. This justifies the slow increase in the absorption peak experimentally
measured at 6.3 eV, which had no satisfactory explanation.Ministerio de Ciencia y Tecnología TIC2001-2969-C03-0
Recomendações técnicas para a reprodução do tambaqui.
Das espécies nativas brasileiras, o tambaqui (Colossoma macropomum) é a mais produzida em cativeiro. Quase a totalidade da produção desse animal puro ocorre nos estados da região Norte do Brasil, com destaque para Rondônia. No Mato Grosso, existe grande produção do híbrido tambacu (tambaqui x pacu-caranha, Piaractus mesopotamicus). Isso se deve à popularidade do pacu-caranha na bacia do rio Paraguai e do repasse de tecnologia, no início dos anos 1980, do Centro Nacional de Pesquisa e Conservação de Peixes Continentais (Cepta), que recomendava a produção do híbrido com o objetivo de explorar o potencial de crescimento do tambaqui associado à resistência do pacu a temperaturas amenas. Atualmente, outro híbrido bastante produzido é o tambatinga, cruzamento de duas espécies amazônicas (tambaqui x pirapitinga, Piaractus brachypomus) com características produtivas parecidas com as do tambacu, mas com destaque para a cor prateada e o opérculo avermelhado, os quais chamam a atenção do consumidor. Desse modo, este manual vai tratar exclusivamente da tecnologia aplicada à reprodução do tambaqui, desenvolvida pela UFRGS, UEM e UFMT com apoio da Embrapa, por meio do Programa de Melhoramento Genético de Organismos Aquáticos, no âmbito do projeto AQUABRASIL.bitstream/item/83462/1/Doc-212-RecomendacoesTecnicasReproducaoTambaqui.pd
Identification and Characterization of Resistance to Meloidogyne enterolobii and M. incognita in Sweetpotato Genotypes
Root-knot nematodes (RKN), Meloidogyne spp., are significant agricultural pests that cause severe economic losses on a wide range of agricultural crops worldwide, including sweetpotato. The economic viability of the sweetpotato industry in the United States is threatened by Meloidogyne enterolobii, which reproduces on sweetpotato cultivars resistant to other RKN species. To address this issue, 69 sweetpotato genotypes were evaluated to identify sources of resistance to M. enterolobii (Me) and M. incognita (Mi). Results showed that twenty-six genotypes were highly resistant to Me and eleven were resistant to Mi, with three genotypes showing resistance to both nematode species. The second objective was to evaluate the penetration, development, and reproduction of Me and Mi in sweetpotato. In resistant genotypes, such as ‘Jewel’, ‘LA14-31’, and ‘LA19-65’, Me remained as J2-stage, with halted development linked to necrotic reaction in response to root penetration by Me. For Mi, the defense response resulted in nematodes dying, maturing as males, or experiencing delayed development into adult females, with a marked reduction in egg production. The third objective involved follow-up histological observations that revealed hypersensitive cells reacting to nematode penetration in resistant genotypes. These findings provide evidence that the resistance mechanism in sweetpotato against Me is mediated by a hypersensitive reaction (HR) response that prevents the feeding site establishment and inhibits nematode development. The fourth objective was to evaluate the root system architectural (RSA) response of sweetpotato genotypes to varying inoculation levels of Me and Mi. Results showed that the genotype ‘LA18-100’ (released as ‘Avoyelles’) had greater RSA attributes compared to other genotypes evaluated. The RSA response to nematode infection was genotype-specific, and not linked to nematode resistance. However, incorporating RSA attributes into the breeding programs holds potential for identifying genotypes with favorable rooting and possible yield traits. Overall, these findings suggest that resistance to both nematode species is available in the sweetpotato genotypes developed at the LSU AgCenter. Resistance to Me appears to be qualitative and involves an HR response that prevents migration and feeding site establishment, whereas resistance to Mi appears to be quantitative, involving delayed nematode development and reductions in egg production in resistant genotypes
Boundary controllability for a 1D degenerate parabolic equation with a Robin boundary condition
In this paper we prove the null controllability of a one-dimensional
degenerate parabolic equation with a weighted Robin boundary condition at the
left endpoint, where the potential has a singularity. We use some results from
the singular Sturm-Liouville theory to show the well-posedness of our system.
We obtain a spectral decomposition of a degenerate parabolic operator with
Robin conditions at the endpoints, we use Fourier-Dini expansions and the
moment method introduced by Fattorini and Russell to prove the null
controllability and to obtain an upper estimate of the cost of controllability.
We also get a lower estimate of the cost of controllability by using a
representation theorem for analytic functions of exponential type.Comment: arXiv admin note: substantial text overlap with arXiv:2304.00178,
arXiv:2302.0119
Wild dogs at stake: deforestation threatens the only Amazon endemic canid, the short-eared dog (Atelocynus microtis)
The persistent high deforestation rate and fragmentation of the Amazon forests are the main threats to their biodiversity. To anticipate and mitigate these threats, it is important to understand and predict how species respond to the rapidly changing landscape. The short-eared dog Atelocynus microtis is the only Amazon-endemic canid and one of the most understudied wild dogs worldwide. We investigated short-eared dog habitat associations on two spatial scales. First, we used the largest record database ever compiled for short-eared dogs in combination with species distribution models to map species habitat suitability, estimate its distribution range and predict shifts in species distribution in response to predicted deforestation across the entire Amazon (regional scale). Second, we used systematic camera trap surveys and occupancy models to investigate how forest cover and forest fragmentation affect the space use of this species in the Southern Brazilian Amazon (local scale). Species distribution models suggested that the short-eared dog potentially occurs over an extensive and continuous area, through most of the Amazon region south of the Amazon River. However, approximately 30% of the short-eared dog's current distribution is expected to be lost or suffer sharp declines in habitat suitability by 2027 (within three generations) due to forest loss. This proportion might reach 40% of the species distribution in unprotected areas and exceed 60% in some interfluves (i.e. portions of land separated by large rivers) of the Amazon basin. Our local-scale analysis indicated that the presence of forest positively affected short-eared dog space use, while the density of forest edges had a negative effect. Beyond shedding light on the ecology of the short-eared dog and refining its distribution range, our results stress that forest loss poses a serious threat to the conservation of the species in a short time frame. Hence, we propose a re-assessment of the short-eared dog's current IUCN Red List status (Near Threatened) based on findings presented here. Our study exemplifies how data can be integrated across sources and modelling procedures to improve our knowledge of relatively understudied species
Search Strategies for Targeted therapy with PDE5i in patients with Pulmonary Hypertension due to heart failure and elevated Pulmonary Vascular Resistance: A Systematic Review
The Effects on Toxicity of Circadian Patterning of Continuous Hepatic Artery Infusion
Long term continuous hepatic artery infusion of FUDR was carried out in 34 rats. In the animals who
received a constant infusion schedule of 15mg/kg/day all died of toxicity with a mean survival of 9.3 days.
If the pattern of the continuous infusion was changed so that over 60% of the infusion was given during
the hours of 3pm to 9pm then all of the animals survived the 14 day infusion. If the maximum dose of
infusion was changed so that 60% of the infusion was given at night from 3am to 9am the infusion
became more toxic and all the animals died in a mean of 5.5 days. Pathologic sectioning of all the livers
reflected the above outcomes with the greatest amount of hepatic necrosis in the animals on the night
cycles. This study underscores the recent advances in chronobiology demonstrating that for continuous
hepatic arterial infusions the timing of delivery is crucial in determining the toxicity
Unraveling the Prevalence of Antibiotic Resistance in Stenotrophomonas maltophilia: Insights into an Emerging Nosocomial Pathogen
Introduction: stenotrophomonas maltophilia is a clinically relevant opportunistic and nosocomial pathogen with increasing concerns regarding antibiotic resistance. Accurate diagnosis and identification are crucial for effective treatment, and misidentification can occur, thereby emphasizing the need for appropriate laboratory testing and surveillance. This review aimed to evaluate the epidemiology, pathogenesis, diagnosis, treatment, and antimicrobial resistance of Stenotrophomonas spp. Materials and Methods. A systematic literature review was conducted using the PubMed Central Database. Inclusion criteria included studies published in open-access scientific journals within the last five years, reporting information on Stenotrophomonas spp. epidemiology, pathogenesis, diagnosis, treatment, and/or antimicrobial resistance. The synthesis of the results involved a narrative synthesis of the findings from the included studies. Results. A total of 25 articles met the inclusion criteria and provided valuable insights into Stenotrophomonas spp. infections. The distribution of reported cases by country, sample type, and antimicrobial resistance patterns was summarized. The prevalence of resistance to various antibiotics was also assessed, highlighting the need for continuous surveillance. Conclusion. This analysis revealed the presence of antimicrobial resistance in Stenotrophomonas spp., particularly in S. maltophilia. The high prevalence of antibiotic resistance underscores the importance of ongoing surveillance and control measures to combat antibiotic resistance. The diverse distribution of S. maltophilia across different sample types emphasizes the need for accurate diagnosis and identification. Addressing antimicrobial resistance in Stenotrophomonas spp. is essential for global public health
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