20 research outputs found
EAACI position paper on occupational rhinitis
The present document is the result of a consensus reached by a panel of experts from European and non-European countries on Occupational Rhinitis (OR), a disease of emerging relevance which has received little attention in comparison to occupational asthma. The document covers the main items of OR including epidemiology, diagnosis, management, socio-economic impact, preventive strategies and medicolegal issues. An operational definition and classification of OR tailored on that of occupational asthma, as well as a diagnostic algorithm based on steps allowing for different levels of diagnostic evidence are proposed. The needs for future research are pointed out. Key messages are issued for each item
The future of medical publication as we move towards the second half of the 21st century
Malignant fibrous histiocytoma of bone associated with type-1 neurofibromatosis - A case report
Von Recklinghausen disease, or neurofibromatosis, is a congenital and
familial disorder with an autosomal dominant pattern of inheritance. The
disease primarily affects ectodermal tissues arising from the neural
crest. It is divided into two basic forms: peripheral (type 1) and
central (type 2), characterized by distinct skeletal and soft-tissue
manifestations(1-6).
Type-l neurofibromatosis usually manifests in early childhood and is
more frequent than the type-2 form of the disease(7,8). Skeletal
abnormalities and dysplasias, including erosive or pressure bone
defects, pseudarthroses, and cranial defects, are diagnosed in
approximately 80% of patients with type-1 neurofibromatosis. In
addition, multiple nonossifying fibromas that predominantly affect the
metaphyseal parts of the long tubular bones tend to develop in patients
with this type of the disease(1).
The most serious, and often fatal, complication of the disease is a
malignant peripheral nerve sheath tumor. Most cases are located within
the soft tissue of the proximal part of an extremity, the buttocks, or
the shoulder girdle. Skeletal involvement usually occurs as a result of
secondary invasion by a soft-tissue lesion; a primary malignant
peripheral nerve sheath tumor in bone is extremely rare(9-12). These
malignant tumors are highly aggressive, with a high propensity for
distant metastases, especially to the lung, liver, and bones(11-13).
We are aware of only one reported case of irradiation-induced malignant
transformation of a neurofibromatous bone lesion of von Recklinghausen
disease to malignant fibrous histiocytoma(14). We describe the case of a
young patient with type-1 neurofibromatosis in whom a malignant fibrous
histiocytoma of bone was diagnosed at the site of fibrous bone lesions
without previous irradiation. The patient was informed that data
concerning the case would be submitted for publication
The Efficacy of Patient Information Sheets in Wrist Arthroscopy: A Randomised Controlled Trial
Unusual presentation of osteoid osteoma of the scaphoid
The small carpal bones are infrequent sites for osteoid osteomas, and
their clinical and imaging pictures may be quite confusing leading to
suspect other etiologies. The authors present herein an unusual case of
osteoid osteoma of the scaphoid superimposed on a wrist injury caused by
a fall on the outstretched hand
Isolated dislocation of the scaphoid
Isolated dislocation of the carpal scaphoid is an extremely rare injury.
The authors report herein a case of a 28-year-old man managed with open
reduction and Kirschner wire fixation. The aim of this study is to
comprehensively present this unusual injury along with its treatment and
to attempt to merge the available experience in the literature in a
suggested algorithm that will guide the surgeon confronted with this
rare problem to treat it promptly and effectively
High rate of radiolucent lines following the cemented original design of the Attune total knee arthroplasty: a systematic review and meta-analysis
Acute Compartment Syndrome of the Forearm Following Autologous Blood Reinfusion: A Case Report
Compartment syndrome is a condition with multiple reported etiologies, and permanent disability may ensue if not treated in a timely fashion. We report the first case, to our knowledge, of acute forearm compartment syndrome caused by intravenous autologous blood reinfusion. The patient underwent forearm fasciotomy, and hematoma was encountered deep to the superficial volar fascia, presumably extravasated from the reinfusion catheter. With the rise in the number of knee and hip arthroplasties, surgeons need a heightened awareness of the possible complications and morbidity associated with a presumed increase in autologous blood reinfusion
