Serum superoxide dismutase levels correlate with disease activity markers in stable bronchiectasis

published_or_final_versio

Airway neutrophilian in bronchiectasis: the role of TNF-α in vivo

Session - Respiratory & Critical Care Medicine: no. S-RC-5published_or_final_versio

Inhaled corticosteroid therapy in bronchiectasis - a 12-month study

published_or_final_versio

Pseudomonas aeruginosa pyocyanin (PYO) down-regulates inducible nitric oxide synthase (iNOS) expression in human bronchus

Session - Respiratory & Critical Care Medicine: no. S-RC-6published_or_final_versio

Up-regulation of circulating adhesion molecules in stable bronchiectasis

Session - Respiratory & Critical Care Medicine: no. S-RC-4published_or_final_versio

Endothelin-1 in the pathogenesis of stable bronchiectasis

published_or_final_versio

Downregulation of endothelin (ET)-1 and interleukin (IL)-8 expression in human respiratory mucosa by Pseudomonas aeruginosa pyocyanin (pyo) and 1-hydroxy-phenazine (HP)

published_or_final_versio

Differential regulation of cytokine-and phorbol ester-induced activation of nuclear factor kappa B by Pseudomonas aeruginosa pyocyanin in human airway epithelial cells

published_or_final_versio

Down-expression of inducible nitric oxide synthase (iNOS) and endothelial (Enos) proteins and mRNA iNOS in bronchiectasis in vivo

published_or_final_versio

Fungal microbiota from rain water and pathogenicity of Fusarium species isolated from atmospheric dust and rainfall dust

In order to determine the presence of Fusarium spp. in atmospheric dust and rainfall dust, samples were collected during September 2007, and July, August, and October 2008. The results reveal the prevalence of airborne Fusarium species coming from the atmosphere of the South East coast of Spain. Five different Fusarium species were isolated from the settling dust: Fusarium oxysporum, F. solani, F. equiseti, F. dimerum, and F. proliferatum. Moreover, rainwater samples were obtained during significant rainfall events in January and February 2009. Using the dilution-plate method, 12 fungal genera were identified from these rainwater samples. Specific analyses of the rainwater revealed the presence of three species of Fusarium: F. oxysporum, F. proliferatum and F. equiseti. A total of 57 isolates of Fusarium spp. obtained from both rainwater and atmospheric rainfall dust sampling were inoculated onto melon (Cucumis melo L.) cv. Piñonet and tomato (Lycopersicon esculentum Mill.) cv. San Pedro. These species were chosen because they are the main herbaceous crops in Almeria province. The results presented in this work indicate strongly that spores or propagules of Fusarium are able to cross the continental barrier carried by winds from the Sahara (Africa) to crop or coastal lands in Europe. Results show differences in the pathogenicity of the isolates tested. Both hosts showed root rot when inoculated with different species of Fusarium, although fresh weight measurements did not bring any information about the pathogenicity. The findings presented above are strong indications that long-distance transmission of Fusarium propagules may occur. Diseases caused by species of Fusarium are common in these areas. They were in the past, and are still today, a problem for greenhouses crops in Almería, and many species have been listed as pathogens on agricultural crops in this region. Saharan air masses dominate the Mediterranean regions. The evidence of long distance dispersal of Fusarium spp. by atmospheric dust and rainwater together with their proved pathogenicity must be taken into account in epidemiological studies