Dynamics of African swine fever virus shedding and excretion in domestic pigs infected by intramuscular inoculation and contact transmission

African swine fever virus (ASFV) is a highly virulent swine pathogen that has spread across Eastern Europe since 2007 and for which there is no effective vaccine or treatment available. The dynamics of shedding and excretion is not well known for this currently circulating ASFV strain. Therefore, susceptible pigs were exposed to pigs intramuscularly infected with the Georgia 2007/1 ASFV strain to measure those dynamics through within- and between-pen transmission scenarios. Blood, oral, nasal and rectal fluid samples were tested for the presence of ASFV by virus titration (VT) and quantitative real-time polymerase chain reaction (qPCR). Serum was tested for the presence of ASFV-specific antibodies. Both intramuscular inoculation and contact transmission resulted in development of acute disease in all pigs although the experiments indicated that the pathogenesis of the disease might be different, depending on the route of infection. Infectious ASFV was first isolated in blood among the inoculated pigs by day 3, and then chronologically among the direct and indirect contact pigs, by day 10 and 13, respectively. Close to the onset of clinical signs, higher ASFV titres were found in blood compared with nasal and rectal fluid samples among all pigs. No infectious ASFV was isolated in oral fluid samples although ASFV genome copies were detected. Only one animal developed antibodies starting after 12 days post-inoculation. The results provide quantitative data on shedding and excretion of the Georgia 2007/1 ASFV strain among domestic pigs and suggest a limited potential of this isolate to cause persistent infection

Sediments and herbivory as sensitive indicators of coral reef degradation

© 2016 by the author(s). Around the world, the decreasing health of coral reef ecosystems has highlighted the need to better understand the processes of reef degradation. The development of more sensitive tools, which complement traditional methods of monitoring coral reefs, may reveal earlier signs of degradation and provide an opportunity for pre-emptive responses. We identify new, sensitive metrics of ecosystem processes and benthic composition that allow us to quantify subtle, yet destabilizing, changes in the ecosystem state of an inshore coral reef on the Great Barrier Reef. Following severe climatic disturbances over the period 2011-2012, the herbivorous reef fish community of the reef did not change in terms of biomass or functional groups present. However, fish-based ecosystem processes showed marked changes, with grazing by herbivorous fishes declining by over 90%. On the benthos, algal turf lengths in the epilithic algal matrix increased more than 50% while benthic sediment loads increased 37-fold. The profound changes in processes, despite no visible change in ecosystem state, i.e., no shift to macroalgal dominance, suggest that although the reef has not undergone a visible regime-shift, the ecosystem is highly unstable, and may sit on an ecological knife-edge. Sensitive, process-based metrics of ecosystem state, such as grazing or browsing rates thus appear to be effective in detecting subtle signs of degradation and may be critical in identifying ecosystems at risk for the future

Understanding Specific Contexts of Antiretroviral Therapy Adherence in Rural South Africa: A Thematic Analysis of Digital Stories from a Community with High HIV Prevalence.

Near-perfect adherence to antiretroviral therapy (ART) is required to achieve the best possible prevention and treatment outcomes. Yet, there have been particular concerns about the challenges of adherence among patients living in resource-limited settings in sub-Saharan Africa. The primary objective of this study was to explore adherence in a low-resourced, rural community of high HIV prevalence in South Africa and to identify specific individual and structural factors that can either challenge or support adherence in this context. We applied digital stories as a qualitative research tool to gain insights into personal contexts of HIV and ART adherence. Through an inductive thematic analysis of twenty story texts, soundtracks and drawings, we explored experiences, understandings, and contexts of the participants and identified potential barriers and facilitators for those on lifelong treatment. We found that many of the stories reflected a growing confidence in the effectiveness of ART, which should be viewed as a key facilitator to successful adherence since this attitude can promote disclosure and boost access to social support. Nevertheless, stories also highlighted the complexity of the issues that individuals and households face as they deal with HIV and ART in this setting and it is clear that an overburdened local healthcare system has often struggled to meet the demands of a rapidly expanding epidemic and to provide the necessary medical and emotional support. Our analysis suggests several opportunities for further research and the design of novel health interventions to support optimal adherence. Firstly, future health promotion campaigns should encourage individuals to test together, or at least accompany each other for testing, to encourage social support from the outset. Additionally, home-based testing and ART club interventions might be recommended to make it easier for individuals to adhere to their treatment regimens and to provide a sense of support and solidarity

Salt of the Earth: Salt as a Driver for Social-Ecological Change in the Communities of the Olifants River Estuary

The West Coast of South Africa is a place that one might feel a sense of desolation, however, the harsh environment is one of beauty and richness. This thesis will look at socio-ecological issues linked to the Olifants River Estuary, and the fishing communities of Ebenheaser, more specifically Papendorp, which is situated approximately 350km north of Cape Town . The issues present can be described in two scales: The first, on a broader ecological scale, the ongoing expansion of mines across the West Coast threatens highly biodiverse habitats that support both ecological and human communities. The proposed new mines East and West of the Olifants River Estuary threatens the ecological systems as well as social systems as communities are directly affected by the health of the estuary (Sowman, 2016). The second scale is concerned on a social level as the communities struggle to maintain their livelihoods and ways of life as fish stocks within the estuary have been on the decline (Sowman, 2009). This decline has forced the need for secondary forms of income for the communities (Olifants River Estuarine Management plan (v.7), 2017). In-order to create a holistic understanding of the issues at hand the thesis will aim to map the patterns and processes of the estuary, its catchment and the landscape which it finds itself in through a lens of extraction. It is proposed that through this method, ecologically activated alternatives to mining might be achieved, ones which harnesses the processes of the natural systems and can provide economic relief and resilience for the community of Papendorp. This intervention also aims to highlight the translation of natural resource extraction towards one of abstraction. Traditionally, many interventions have failed to fully understand the interwoven nature of ecologies and the Anthropocene, this has led to the marginalization of groups (such as small-scale fishers) and the disregard for their cultural heritage and rights to natural resources. This multi-scalar approach aims to include all aspects of the study area, ecological, cultural, social, and economical to create a layered approach that allows for a detailed understanding of the site, its challenges and its opportunities. It is hoped that through this approach the outcome will allow for a better integration of ecology and conservation with social and economic aspects and therefore produce an intervention that aids in the improvement of both communities and ecologies

Adequate Protection and Administrative Expense: Toward a Uniform System for Awarding Superpriorities

Part I of this Note reviews the legislative history of relevant Code sections and the Code language that pertain to the granting of adequate protection. Section 361 of the Code provides for three types of adequate protection. Sections 362, 363, and 364 set out instances when actions by the trustee that result in a decrease in the value of a secured party\u27s interest require the provision of adequate protection. Finally, sections 503 and 507 designate circumstances when prepetition secured creditors are eligible to receive administrative expenses. Section 507(b) authorizes allowance of an administrative expense claim when the adequate protection provided to a secured creditor fails. Part II of this Note analyzes the conditions a creditor must satisfy to receive adequate protection. This Part argues that a creditor\u27s request to the court for adequate protection should be enough to invoke the right to administrative expense priority and suggests a Code revision to promote such an outcome. Part III addresses the issue, currently left unresolved by the Code and the Bankruptcy Rules, of whether adequate protection must be requested from and approved by the court. This Note concludes by proposing an effective system of notice and routine court approval that would address the major policy concerns of private agreements and could be provided with only minor revisions of the Bankruptcy Rules

Forming Leaders to Flourish in Crises

Challenges of learship formation duing crisis

A critical literacy and narrative analysis of African Storybook folktales for early reading

Thesis (M.A. (Applied Language and Literacy Education))--University of the Witwatersrand, Faculty of Humanities, 2017This study critically analyses a set of folktales from the African Storybook website, which is an open licence digital publishing platform supporting early reading in Africa (www.africanstorybook.org). The selected folktales were mostly written by educators and librarians working in the African Storybook project pilot sites. The folktales were illustrated and published as indigenous African language and English storybooks during 2014 to 2015. The analysis is centrally concerned with the settings in which the folktales take place (with a distinction made between space, place and time), and the age and gender associated with central characters. The analytical tools used and the perspectives applied are drawn predominantly from post-colonial studies, African feminism, critical literacy, broad folktale scholarship, and theory from local – as opposed to global – childhoods. The analysis is interested in the conventions of the folktale genre, as it is constructed in the narratives by the writers. The three central findings with regards to the settings of folktales are as follows: (i) 90% of the folktales are set in rural environments in or near villages or small settlements. The somewhat idealised villages and settlements appear to have been relatively untouched by modern communications and infrastructure, and represent a “nostalgic, imagined past”. (ii) The study found that 75% of the folktales are set in the remote past, indexical of the folktale genre’s oral roots. (iii) Supernatural characters, objects and events occur in nearly 75% of the folktales. This suggests a possible interpretive space of intersecting temporalities and dimensions of existence, as well as possibilities for imaginative problem-solving. In addition, it raises challenging questions about the limits of human agency. The study also found that the ASb folktales, perhaps somewhat unsurprisingly for a genre that tends to employ archetypes and stereotypes, seemingly offer no characterisation outside of heteronormative family roles. But despite the heteronormativity and narrowly-defined family roles, especially for women characters, the folktales also present other positions for female gendered characters, and by extension for girl child readers – courageous, interesting, clever and unconventional female characters are in no shortage in these narrative populations. The findings suggest that the ASb folktales provide a range of identity positions for both girls and boys in African contexts, and my study reflects on how educators might navigate this complex territory. In particular, the findings point to how teachers and other adult caregivers might balance the moral and cultural lessons in folktales with the need for children to imagine and construct different worlds and positions for themselves.MT201

Post-Apartheid Film Industry

Representation, Creativity and Commercialism in the Post-Apartheid Film Industry Since the advent of democracy in 1994, South Africa has been in the process of redefining itself as a nation. The newly elected government recognised the potential role of cinema in democratic transformation and economic empowerment and established a number of strategic interventions and government bodies to foster the growth of the local industry. Similar to other forms of cultural production, cinema is informed by the national Constitution of 1996, which celebrates multiculturalism, freedom of expression, and transformation. However, it is questionable whether this vision is compatible with the state's ambition to build an internationally competitive, and commercially successful film industry. This paper provides a critical analysis of the economic and ideological workings of the post-apartheid feature film industry. The focus is on international co-productions, which have been encouraged by the state since such arrangements are seen to..

The representation and mediation of national identity in the production of post-apartheid, South African cinema

Includes bibliographical references (p. 218-236).In 1994, South Africa was emancipated from apartheid, and in 1996, a new democratic Constitution was released. This charter envisioned a progressive society and placed emphasis on equality, multiculturalism, reconciliation and freedom. The state targeted the cultural industries, including cinema, to carry this new vision to the nation. The problem, however, was that the production, exhibition and distribution infrastructure inherited from apartheid was not only dominated by Hollywood, but also exclusively catered for the white sector of the nation. This monopolised, racially skewed structure continues to pose an obstacle to the dissemination of progressive identities and the sustainability of local cinema. Through an analysis of relevant film policy, industry structure and specific cinematic texts, this study aims to trace the intersection between the dynamics of national identity representation and South Africa's political and economic position as a developing nation in the global marketplace. The research presented took place over a period of three years (2007-2010) and incorporated both quantitative and qualitative methods