1,342 research outputs found

    The Growth of Industrial Sectors: Theoretical Insights and Empirical Evidence from U.S. Manufacturing

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    In this paper, we study the growth rates of 4-digit sectors in U.S. manufacturing. Two measures of size (value of shipments, value added) are considered, for each of the 38 years (1959-1996) of a sample of 458 4-digit sectors, drawn from the NBER Manufacturing Productivity database. Whole sample results are partly in line with firm growth facts: (i) sectoral growth rates are distributed according to heavy-tailed Subbotin distributions, with shape coefficient between 1.0 (Laplace) and 1.5; (ii) the volatility of growth rates is decreasing with respect to size, with a scaling exponent varying over time, but always between -0.20 and -0.10. Preliminary analyses on more homogeneous groups cast doubts on the evidence of scaling, but leave basically unaffected the distributional properties of sectoral growth. These results shed light on the role of inter-firm correlations, market concentration, and positive intersectoral feedbacks as drivers of meso-economic dynamics.Sectoral Growth, Subbotin Distribution, Scaling, U.S. Manufacturing

    Scientific and Technological Regimes in Nanotechnology: Combinatorial Inventors and Performance

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    Academics and policy makers are questioning about the relation between science and technology in the emerging field of nano science and technology (NST) and the effectiveness of different institutional regimes. We analyze the performance of inventors in the NST using multiple indicators. We clustered patents in three groups according to the scientific curricula of the inventors. The first two groups are composed by patents whose inventors respectively are all authors of at least one scientific publication in the NST and none of then has obtained a scientific publication in that field. Thirdly, we isolated those patents that have at least one inventor, who is also author of at least one scientific publication in the NST. The underlining presumption of this classification is that of a proxy of different institutional search regimes of the inventive activity; pure academic research, pure industrial R&D, and academic-industrial research partnerships.Science-Technology Relation, Emerging Field, Nanotechnology, Patent Quality, Inventive Productivity.

    IVOA Recommendation: IVOA Support Interfaces

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    This document describes the minimum interface that a (SOAP- or REST-based) web service requires to participate in the IVOA. Note that this is not required of standard VO services developed prior to this specification, although uptake is strongly encouraged on any subsequent revision. All new standard VO services, however, must feature a VOSI-compliant interface. This document has been produced by the Grid and Web Services Working Group. It has been reviewed by IVOA Members and other interested parties, and has been endorsed by the IVOA Executive Committee as an IVOA Recommendation. It is a stable document and may be used as reference material or cited as a normative reference from another document. IVOA's role in making the Recommendation is to draw attention to the specification and to promote its widespread deployment. This enhances the functionality and interoperability inside the Astronomical Community

    Financial Patenting in Europe

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    We take a first look at financial patents at the European Patent Office (EPO). As is the case at the US Patent and Trademark Office (USPTO), the number of financial patents in Europe has increased significantly in parallel with significant changes in payment and financial systems. Scholars have argued that financial patents, like other business methods patents, have low value and are owned for strategic reasons rather than for protecting real inventions. We find that established firms in non-financial sectors with diversified patent portfolios own a large share of financial patents at the EPO. However, new specialized technology providers in the financial area also hold a number of such patents. Decisions on the financial patent applications take longer and they are more likely to be refused by the patent office, suggesting greater uncertainty over validity than for other patents. They are also more likely to be opposed, which is consistent with the fact that their other economic value indicators are higher.market valuation, intangible assets, patents, software, Europe

    The growth of industrial sectors: Theoritical insights and empirical evidence from US manufacturing

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    In this paper, we study the growth rates of 4-digit sectors in U.S. manufacturing. Two measures of size (value of shipments, value added) are considered, for each of the 38 years (1959-1996) of a sample of 458 4-digit sectors, drawn from the NBER Manufacturing Productivity database. Whole sample results are partly in line with firm growth facts: (i) sectoral growth rates are distributed according to heavy-tailed Subbotin distributions, with shape coefficient between 1.0 (Laplace) and 1.5; (ii) the volatility of growth rates is decreasing with respect to size, with a scaling exponent varying over time, but always between -0.20 and -0.10. Preliminary analyses on more homogeneous groups cast doubts on the evidence of scaling, but leave basically unaffected the distributional properties of sectoral growth. These results shed light on the role of inter-firm correlations, market concentration, and positive intersectoral feedbacks as drivers of meso-economic dynamics

    Modelling credit risk for innovative firms: the role of innovation measures

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    Financial constraints are particularly severe for R&D projects of SMEs, which cannot generally rely on equity markets and, in the EU, on a sufficiently developed VC industry. If innovative SMEs have to depend on banks to finance their R&D projects, it is particularly important to develop models able to estimate their probability of default (PD) in consideration of their peculiar features. Based on the signaling value of some innovative assets, the purpose of this paper is to show the importance to include them into models which have proved to be successful for SMEs. To this end, we take a logit model and test it on a unique dataset of innovative SMEs (based on PATSTAT database, EPO BULLETIN and AMADEUS) to estimate a two-year PD with default years 2006-2008. In the regression analysis the innovation-related variables are two in order to account for R&D productivity at the level of the firm and to consider the value of the inventive output. Our analyses first address measurement issues concerning innovation-related variable and then show that, while the accounting variables and the patent value are always significant with the expected sign, the patent number per se reduces the PD only in the presence of an appropriate equity level.innovative SMEs; default probability; patent value

    Many Strong Voices: Outline for an assessment project design

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    This document defines, guides, and supports the development and implementation of a full assessment of vulnerability and adaptation to climate change in Small Island Developing States (SIDS), under the Many Strong Voices (MSV) programme. A summary of impacts of climate change on SIDS is provided along with a literature review and analysis of vulnerability and adaptation to climate change in SIDS, supplemented by consultations with SIDS partners, to indicate data availability and quality along with how to fill in data gaps. Then, an initial structure for the assessment is detailed with recommendations for implementing a SIDS assessment of climate change vulnerability and adaptation.Recommendations describe the need for the work, the scientific methods to adopt, the focus on case studies, and the emphasis on a problem- driven and action research approach involving local consultations.Research, policy, and practice outcomes of the assessment are also described

    Use of an inertia-less virtual synchronous machine within future power networks with high penetrations of converters

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    Conventional converter models for wind turbines and Voltage Source HVDC links, as submitted to System Operators, typically use dq-axis controllers with current injection (DQCI). Recent work carried out by the authors has proven that for DQCI converter-interfaced sources there are overall penetration limits, i.e. the 'tipping points' beyond which the system will become unstable. Initial investigations of this "tipping point", based on a reduced model of the transmission system of Great Britain using phasor simulation within DIgSILENT PowerFactory, are reviewed briefly in this paper. The 'tipping points' relating to maximum penetration of DQCI converter-interfaced sources are subsequently investigated in this paper using a higher fidelity three-phase dynamic power system model in Matlab Simulink. Additionally, a new converter controller, termed here as Virtual Synchronous Machine Zero Inertia (VSM0H), is described and implemented in the model. It is shown that, in principle, it is possible to significantly increase the penetration of converter based generation (up to 100% of installed capacity) without reaching a stability constraint

    Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum.

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    Autosomal recessive hereditary spastic paraplegia (ARHSP) with thin corpus callosum (TCC) is a common and clinically distinct form of familial spastic paraplegia that is linked to the SPG11 locus on chromosome 15 in most affected families. We analyzed 12 ARHSP-TCC families, refined the SPG11 candidate interval and identified ten mutations in a previously unidentified gene expressed ubiquitously in the nervous system but most prominently in the cerebellum, cerebral cortex, hippocampus and pineal gland. The mutations were either nonsense or insertions and deletions leading to a frameshift, suggesting a loss-of-function mechanism. The identification of the function of the gene will provide insight into the mechanisms leading to the degeneration of the corticospinal tract and other brain structures in this frequent form of ARHSP
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