ASSOCIATION BETWEEN HASHIMOTO’S THYROIDITIS AND DEPRESSION

Hashimoto’s thyroiditis is a disease of the thyroid gland which affects the body in various ways leading to somatic complications. In addition to that, it affects the patient’s mental health. The extent of psychiatric diseases in patients with Hashimoto’s thyroiditis is not extensively explored. The primary objective of this study was to find the association between Hashimoto’s disease and depression in female patients aged 36-50 from North America/Central America. Questionnaires were designed to assess the extent of possible depression in those patients. We compared 115 cases to 188 controls. After analyzing results, we found that relative risk for developing depression in patients with hashimoto’s disease was 1.7202 (95% CI 1.4722- 2.0099, p value&lt; 0.001). Thus, we concluded that Hashimoto’s disease is associated with increased risk of development of depression in a given sample.</jats:p

OXIDATIVE STRESS AND ANTIOXIDANTS WITH EMPHASIS ON AGEING (Review Article)

Numerous theories have been postulated to understand the process of aging. One of them links degenerative senescence to reactive oxygen species (ROS), which are natural byproducts of oxygen metabolism. Understanding and supporting this theory may be of great importance due to number of reasons. Firstly, there are well-established risk factors that can increase the production of ROS in our body. Secondly, there are different types of antioxidants that can neutralize toxic effects of ROS. Examples of antioxidants include natural enzymes produced in our body, as well as certain exogenous supplements. Moreover, antioxidant supplementation is already offered by some facilities as a hope to decrease age-related complications. Therefore, it is crucial to understand, how ROS is involved in the process of aging and if there is any evidence how alteration in ROS and antioxidants levels influence the process of ageing.</jats:p