612 research outputs found

    The passage of Zeppelin

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    Thesis (M.S.V.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1982.MICROFICHE COPY AVAILABLE IN ARCHIVES AND ROTCH.Includes bibliographical references.by Lorilee S. Garbowski.M.S.V.S

    Residual erythropoiesis protects against myocardial hemosiderosis in transfusion-dependent thalassemia by lowering labile plasma iron via transient generation of apotransferrin

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    Cardiosiderosis is a leading cause of mortality in transfusion-dependent thalassemias. Plasma non-transferrin-bound iron and its redox-active component, labile plasma iron, are key sources of iron loading in cardiosiderosis. Risk factors were identified in 73 patients with or without cardiosiderosis. Soluble transferrin receptor-1 levels were significantly lower in patients with cardiosiderosis (odds ratio 21). This risk increased when transfusion-iron loading rates exceeded the erythroid transferrin uptake rate (derived from soluble transferrin receptor-1) by >0.21mg/kg/d (odds ratio 48). Labile plasma iron was >3-fold higher where this uptake rate threshold was exceeded, but non-transferrin-bound iron and transferrin saturation were comparable. Cardiosiderosis risk was also decreased in patients with low liver iron, ferritin and labile plasma iron, or high bilirubin, reticulocyte counts or hepcidin. We hypothesized that high erythroid transferrin uptake rate decreases cardiosiderosis through increased erythroid re-generation of apotransferrin. To test this, iron uptake and intracellular reactive oxygen species were examined in HL-1 cardiomyocytes under conditions modelling transferrin effects on non-transferrin-bound iron speciation with ferric citrate. Intracellular iron and reactive oxygen species increased with ferric citrate concentrations especially where iron-to-citrate ratios exceeded 1:100, i.e. conditions favoring kinetically labile monoferric rather than oligomer species. Excess iron-binding equivalents of apotransferrin inhibited iron uptake, decreased intracellular reactive oxygen species and labile plasma iron, under conditions favoring monoferric species. In conclusion, high transferrin iron utilisation, relative to the transfusion-iron load rate, decreases the cardiosiderotic risk. A putative mechanism is the transient re-generation of apotransferrin by an active erythron, rapidly binding labile plasma iron-detectable ferric monocitrate species

    Book Review: Anna Niedźwiedź and Kaja Kajder, eds., Mapy miasta: Dziedzictwa i sacrum w przestrzeni Krakowa / Maps of the City: Heritages and the Sacred within Kraków’s Cityscape.

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    The book Maps of the City is the result of an exhibition at The Seweryn Udziela Ethnographic Museum in Kraków that was held between November 2017 and February 2018. As the subtitle makes clear, the exhibition focused on the place of heritage and the sacred within Kraków’s cityscape, together with the relationship between the two, both for the city’s residents and visitors. The latter group includes pilgrims. The curator of the exhibition was Anna Niedźwiedź, a cultural anthropologist at Jagiellonian University and author of The Image and the Figure: Our Lady of Częstochowa in Polish Culture and Popular Religion (2010). She is also one of the editors of the book. This richly illustrated volume is no mere catalogue of a museum exhibition. The editors, together with their team of anthropologists, have written essays based on original research that forms the basis of the exhibition and the chapters of the book. What we have in the end is a book that is both for the broader reading public and the scholar, and due to its bilingual form, both for Polish and English readers

    The War in Ukraine and Political Theology in Poland

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    In the broadest of terms, political theology can be defined as “the analysis of political arrangements (including cultural-psychological, social, and economic aspects) from the perspective of God’s ways with the world.”1 Since the world changes, as do the politics accompanying them, political theology is of necessity a dynamic branch of the theological enterprise. The editors to the second edition of The Wiley Blackwell Companion to Political Theology note a number of such changes that justify the expanded second edition of their handbook, including—what is most pertinent for understanding political theology at present in Poland—“the discourse on religion and violence, and new modalities of war.”2 A substantive chapter in this vein, by Emmanuel Katongole, starts with a news item concerning civil war in Ivory Coast in 2011. The author follows this sample news stressing the problems of “power struggle, corruption, sham elections, and civil war that characterize politics of much of sub-Saharan Africa.”3 Political theology is not new to Poland, but obviously the full- scale invasion by Russia of the neighboring Ukraine on February 24, 2022, together with the accompanying atrocities has had a similar impact in the field in the country to that of a number of the authors in the handbook. This article will provide an introductory view of a significant part of this ongoing response in the country

    The Pianist

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    This is a review of The Pianist (2002)

    Katyn

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    This is a review of Katyn (2007)

    Catholicism in the New Poland: A Religion and Society in Transition

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    Excerpt: Polish society is divided along a number of lines; hardly unusual in any contemporary pluralistic society. The new divisions have not been adequately named. Michał Kuź, a Polish political scientist, has coined the self-explanatory terms “localists” and “internationalists” to describe perhaps the most pertinent current divide within European societies.1 These worldview divides are also visible along political party lines. The proportions of the parties of the divide are naturally different in Poland than in countries of the old Europe. It is relatively easy to indicate which of the parties in the political landscape of the country within the localist and internationalist divide places more emphasis on patriotism.2 Poles generally consider themselves European and their attitude toward the European Union remains quite positive across the board, with only a small group of genuine Eurosceptics present in the society.3 To put it in more traditional terms, in Polish society there is a small group of cosmopolitans and strong nationalists at opposite ends of the spectrum, while most citizens range somewhere in between. These divisions naturally play out at various levels in the field of religious life as well. However, to begin to understand the place of religion in Polish society, it is best to start at its most basic unit: the family

    The Catholic Imagination in Martin Scorsese\u27s The Last Waltz

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    The author examines Martin Scorsese\u27s rockumentary The Last Waltz of 1978 as an encounter between the communitarian focus of the Catholic imagination (cf. Greeley Catholic Imagination) and the more individualistic ethos dominant in contemporary society (cf. Taylor Ethics of Authenticity). He claims the encounter not only shapes Scorsese\u27s fiction films but also exhibit\u27s his notion of the filmmaker\u27s mission. The subject matter of the film lends itself to this examination because a rock band balances between the individuality of its performers and the communality of its form. Moreover, overt religious values and themes of the film are explored in relation to the above questions

    Katyn

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    This is a review of Katyn (2007)
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