78 research outputs found
Rhodium-Catalyzed Asymmetric Intramolecular Hydroamination of Unactivated Alkenes
One for the Rh(oad): The first rhodium-catalyzed asymmetric intramolecular hydroamination of unactivated olefins was developed by using dialkylbiaryl phosphine ligands (see scheme; cod=1,5-cyclooctadiene, Cy=cyclohexyl). A variety of 2-methylpyrrolidines have been synthesized with high enantioselectivities.National Institutes of Health (U.S.) (Grant GM46059)Merck & Co.Boehringer Ingelheim PharmaceuticalsNational Institutes of Health (U.S.) (GM 1S10RR13886-01
Pinolide, a New Nonenolide Produced by Didymella pinodes, the Causal Agent of Ascochyta Blight on Pisum sativum
Strategies for monitoring and combating resistance to combination kinase inhibitors for cancer therapy
ChemInform Abstract: Stereoselective Synthesis of the Bacterial DNA Primase Inhibitor Sch 642305 and Its C-4 Epimer.
ChemInform Abstract: Palladium-Catalyzed Asymmetric Dearomatization of Naphthalene Derivatives.
Stereoselective Total Synthesis and Absolute Configuration of the Natural Decanolides (-)-Microcarpalide (I) and (+)-Lethaloxin (II). Identity of (+)-Lethaloxin and (+)-Pinolidoxin.
The Total Synthesis and Biological Properties of the Cytotoxic Macrolide FD-891 (Ia) and Its Non-Natural (Z)-C12 Isomer (Ib).
- …
