1,293 research outputs found

    Method and Meaning: Selections from the Gettysburg College Collection

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    What is art historical study and how it should be carried out are fundamental questions the exhibition Method and Meaning: Selections from the Gettysburg College Collection intends to answer. This student-curated exhibition is an exciting academic endeavor of seven students of art history majors and minors in the Art History Methods course. The seven student curators are Shannon Callahan, Ashlie Cantele, Maura D’Amico, Xiyang Duan, Devin Garnick, Allison Gross and Emily Zbehlik. As part of the class assignment, this exhibition allows the students to explore various art history methods on individual case studies. The selection of the works in the exhibition reflects a wide array of student research interests including an example of 18th century Chinese jade chime stone, jade and bronze replicas of ancient Chinese bronze vessels, a piece of early 20th century Chinese porcelain, oil paintings by Pennsylvania Impressionist painter Fern Coppedge, prints by Salvador Dalí and by German artist Käthe Kollwitz, and an early 20th century wood block print by Japanese artist Kawase Hasui. [excerpt]https://cupola.gettysburg.edu/artcatalogs/1014/thumbnail.jp

    Righting a Wrong

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    Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms.

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    Interstitial pulmonary fibrosis induced by intratracheal instillation of bleomycin (BL) involves an excess production of reactive oxygen species, unavailability of adequate levels of NAD and ATP to repair the injured pulmonary epithelium, and an overexuberant lung collagen reactivity followed by deposition of highly cross-linked mature collagen fibrils resistant to enzymatic degradation. In the present study, we have demonstrated that dietary supplementation with taurine and niacin offered almost complete protection against the lung fibrosis in a multidose BL hamster model. The mechanisms for the protective effect of taurine and niacin are multifaceted. These include the ability of taurine to scavenge HOCl and stabilize the biomembrane; niacin's ability to replenish the BL-induced depletion of NAD and ATP; and the combined effect of taurine and niacin to suppress all aspects of BL-induced increases in the lung collagen reactivity, a hallmark of interstitial pulmonary fibrosis. It was concluded from the data presented at this Conference that the combined treatment with taurine and niacin, which offers a multipronged approach, will have great therapeutic potential in the intervention of the development of chemically induced interstitial lung fibrosis in animals and humans

    Gerhard Richter: Recovery and Memory in Postwar Germany

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    Gerhard Richter explored themes of memory and national identity in a society with a controversial past and a difficult recovery. He broke the silence that permeated the country and created a dialogue about remembering, memorializing, and politics. After World War II, Germany had difficulty facing the atrocities of the war and ignored the flaws in the country’s recovery. Richter witnessed first hand the social and political struggles of the country as a citizen of Nazi Germany and the German Democratic Republic, societies that required strict conformity to their ideologies. Upon his escape to West Germany, where he was exposed to Pop Art, Abstract Expressionism, and the expected rejection of Socialism, Richter forged a painting career devoid of stylistic or content conformity. Richter’s family paintings and his October 18, 1977 series from 1988 directly confront Germany’s struggle to recover from the Second World War. The family paintings address the ways in which World War II affected his own family’s dynamic and identity. The October 18, 1977 series comments on the events involving the Baader-Meinhof group inside Stammheim Prison, and in doing so highlights social unrest and political controversy in Germany in the 1970’s. Richter’s refusal to stay silent about these issues allowed him to bring to light the reality of Germany’s condition. Although these pieces were painted in a photorealistic style, the literal blurring of these images makes a statement about clarity, perception, and reality while toying with the norms associated with the mediums of painting and photography. Richter addresses unspeakable topics with an unconventional painting style to create a dynamic juxtaposition of ambiguity and directness

    We\u27ll See You Tomorrow

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    On July 14th, 2015, Hannah climbed to the top of Half Dome, a stunning rock formation that rises thousands of feet above the valley floor at Yosemite National Park. She had talked about wanting to climb to the top of this breathtaking cliff for years and frequently mentioned that she had to tackle this feat “before she died.” I was amazed and proud to see photos of her impressive accomplishment, and wondered what she might achieve next. On July 21st, 2015, Hannah committed suicide. [excerpt

    The Dento-Gingival Junction as Seen with Light Microscopy and Scanning Electron Microscopy

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    The purpose of this paper is to review the anatomical relationship of the Dento-Gingival Junction as seen in the human dentition. The junction is described under light microscopy and then reviewed as seen in the SEM with the authors\u27 unpublished findings. The authors\u27 material was derived from extracted human teeth with remaining marginal gingival tissue. The specimens were fixed with 2% glutaraldehyde in O.15M sodium cacodylate buffer (pH 7.2) for 24 h. The specimens were then washed and freeze-fractured in Freon 113 using liquid nitrogen. Afterwards they were processed by freeze-drying or CPD methods, coated with gold, and placed in the scanning electron microscope (SEM) for viewing. These specimens demonstrated the presence of numerous Sharpey\u27s fibers at the cemental surface. A large number of fibrils intermingled with the fibers to produce a dense mass of tissue. Junctional epithelium, with the adjacent homogeneous dental cuticle was demonstrated. Plaque deposits on the tooth surface extended to a cell-free zone. Morphological detail viewed with SEM and light microscopy are compared

    Direct measurement of actin polymerization, in vitro, in response to various pH regimes

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    The pH dependency of actin polymerization in vitro was demonstrated by measuring single actin filament• lengths at various pH regimes with negative staining high resolution electron microscopy. The average length of the actin filaments in a solution buffered to pH 8.0 was 12.65um, while at pH 6.0 the average length was 2.5um. Purified G-actin from chicken skeletal muscle was polymerized upon the addition of l0mM MgC12. The polymerization process was monitored via an increase in UV absorbance at 232nm. The critical concentrations of actin were determined at various pHs by the pellet assay. These kinetic studies indicated that at an acidic pH there is an increase in the number of F-actin nucleation sites and a decrease in the total polymer mass. Therefore, at pH 6.0, the polymerization reaction results in oligomer formation rather than polymer formation. By contrast, at pH 8.0, there are less F-actin nuclei, but a larger polymer mass, which is suggestive of polymer formation. These observations were demonstrated by direct measurement of the filament lengths in the electron microscope. Thus actin polymerization in vitro is a pH dependent process. Given these results, we propose that intracellular pH may affect the assembly state of actin filaments, which in turn maintains the cellular architecture and may regulate a variety of cellular activities.California State University, Northridge. Department of Biology.Includes bibliographical references (pages 48-49

    The history of degenerate (bipartite) extremal graph problems

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    This paper is a survey on Extremal Graph Theory, primarily focusing on the case when one of the excluded graphs is bipartite. On one hand we give an introduction to this field and also describe many important results, methods, problems, and constructions.Comment: 97 pages, 11 figures, many problems. This is the preliminary version of our survey presented in Erdos 100. In this version 2 only a citation was complete
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