2,207 research outputs found
Metabolic and nutritional status changes after 10% weight loss in severely obese patients treated with laparoscopic surgery vs integrated medical treatment
Noninvasive Evaluation of Abdominal Fat and Liver Changes Following Progressive Weight Loss in Severely Obese Patients Treated with Laparoscopic Gastric Bypass.
Physical Processes Controlling Earth's Climate
As background for consideration of the climates of the other terrestrial planets in our solar system and the potential habitability of rocky exoplanets, we discuss the basic physics that controls the Earths present climate, with particular emphasis on the energy and water cycles. We define several dimensionless parameters relevant to characterizing a planets general circulation, climate and hydrological cycle. We also consider issues associated with the use of past climate variations as indicators of future anthropogenically forced climate change, and recent advances in understanding projections of future climate that might have implications for Earth-like exoplanets
Phase Diagram for a 2-D Two-Temperature Diffusive XY Model
Using Monte Carlo simulations, we determine the phase diagram of a diffusive
two-temperature XY model. When the two temperatures are equal the system
becomes the equilibrium XY model with the continuous Kosterlitz-Thouless (KT)
vortex-antivortex unbinding phase transition. When the two temperatures are
unequal the system is driven by an energy flow through the system from the
higher temperature heat-bath to the lower temperature one and reaches a
far-from-equilibrium steady state. We show that the nonequilibrium phase
diagram contains three phases: A homogenous disordered phase and two phases
with long range, spin-wave order. Two critical lines, representing continuous
phase transitions from a homogenous disordered phase to two phases of long
range order, meet at the equilibrium the KT point. The shape of the
nonequilibrium critical lines as they approach the KT point is described by a
crossover exponent of phi = 2.52 \pm 0.05. Finally, we suggest that the
transition between the two phases with long-range order is first-order, making
the KT-point where all three phases meet a bicritical point.Comment: 5 pages, 4 figure
Data Mining a Medieval Medical Text Reveals Patterns in Ingredient Choice That Reflect Biological Activity against Infectious Agents
We used established methodologies from network science to identify patterns in medicinal ingredient combinations in a key medieval text, the 15th-century Lylye of Medicynes, focusing on recipes for topical treatments for symptoms of microbial infection. We conducted experiments screening the antimicrobial activity of selected ingredients. These experiments revealed interesting examples of ingredients that potentiated or interfered with each other’s activity and that would be useful bases for future, more detailed experiments. Our results highlight (i) the potential to use methodologies from network science to analyze medieval data sets and detect patterns of ingredient combination, (ii) the potential of interdisciplinary collaboration to reveal different aspects of the ethnopharmacology of historical medical texts, and (iii) the potential development of novel therapeutics inspired by premodern remedies in a time of increased need for new antibiotics.The pharmacopeia used by physicians and laypeople in medieval Europe has largely been dismissed as placebo or superstition. While we now recognize that some of the materia medica used by medieval physicians could have had useful biological properties, research in this area is limited by the labor-intensive process of searching and interpreting historical medical texts. Here, we demonstrate the potential power of turning medieval medical texts into contextualized electronic databases amenable to exploration by the use of an algorithm. We used established methodologies from network science to reveal patterns in ingredient selection and usage in a key text, the 15th-century Lylye of Medicynes, focusing on remedies to treat symptoms of microbial infection. In providing a worked example of data-driven textual analysis, we demonstrate the potential of this approach to encourage interdisciplinary collaboration and to shine a new light on the ethnopharmacology of historical medical texts
Finding network communities using modularity density
Many real-world complex networks exhibit a community structure, in which the modules correspond to actual functional units. Identifying these communities is a key challenge for scientists. A common approach is to search for the network partition that maximizes a quality function. Here, we present a detailed analysis of a recently proposed function, namely modularity density. We show that it does not incur in the drawbacks suffered by traditional modularity, and that it can identify networks without ground-truth community structure, deriving its analytical dependence on link density in generic random graphs. In addition, we show that modularity density allows an easy comparison between networks of different sizes, and we also present some limitations that methods based on modularity density may suffer from. Finally, we introduce an efficient, quadratic community detection algorithm based on modularity density maximization, validating its accuracy against theoretical predictions and on a set of benchmark networks
Climates of Warm Earth-like Planets I: 3-D Model Simulations
We present a large ensemble of simulations of an Earth-like world with
increasing insolation and rotation rate. Unlike previous work utilizing
idealized aquaplanet configurations we focus our simulations on modern
Earth-like topography. The orbital period is the same as modern Earth, but with
zero obliquity and eccentricity. The atmosphere is 1 bar N-dominated with
CO=400 ppmv and CH=1 ppmv. The simulations include two types of
oceans; one without ocean heat transport (OHT) between grid cells as has been
commonly used in the exoplanet literature, while the other is a fully coupled
dynamic bathtub type ocean. The dynamical regime transitions that occur as day
length increases induce climate feedbacks producing cooler temperatures, first
via the reduction of water vapor with increasing rotation period despite
decreasing shortwave cooling by clouds, and then via decreasing water vapor and
increasing shortwave cloud cooling, except at the highest insolations.
Simulations without OHT are more sensitive to insolation changes for fast
rotations while slower rotations are relatively insensitive to ocean choice.
OHT runs with faster rotations tend to be similar with gyres transporting heat
poleward making them warmer than those without OHT. For slower rotations OHT is
directed equator-ward and no high latitude gyres are apparent. Uncertainties in
cloud parameterization preclude a precise determination of habitability but do
not affect robust aspects of exoplanet climate sensitivity. This is the first
paper in a series that will investigate aspects of habitability in the
simulations presented herein. The datasets from this study are opensource and
publicly available.Comment: 27 pages ApJS accepted. Expanded Introduction and several additional
figure
- …
