Instability of the salinity profile during the evaporation of saline groundwater

We investigate salt transport during the evaporation and upflow of saline groundwater. We describe a model in which a sharp evaporation-precipitation front separates regions of soil saturated with an air-vapour mixture and with saline water. We then consider two idealised problems. We first investigate equilibrium configurations of the fresh-water system when the depth of the soil layer is finite, obtaining results for the location of the front and for the upflow of water induced by the evaporation. Motivated by these results, we develop a solution for a propagating front in a soil layer of infinite depth, and we investigate the gravitational stability of the salinity profile which develops below the front, obtaining marginal linear stability conditions in terms of a Rayleigh number and a dimensionless salt saturation parameter. Applying our findings to realistic parameter regimes, we predict that salt fingering is unlikely to occur in low-permeability soils, but is likely in high-permeability (sandy) soils under conditions of relatively low evaporative upflow

Fantasies of subjugation: a discourse theoretical account of British policy on the European Union

The decision by the UK government to hold a referendum on Britain’s membership of the European Union (EU) marks an important development in policy towards the EU. Policy changes of this kind must be understood in the historical and political context in which they occur. This includes the framing of the policy issues within public discourse. In the UK, policies are formed in a discursive environment which is overwhelmingly hostile towards the EU. Debates are structured by a predominantly Euroskeptic discourse which emphasizes the UK’s separation and heterogeneity from the rest of the EU. Drawing on the logics of critical explanation, this article examines the structure and affective power of Euroskeptic discourses which dictate the terms of the EU debate. It presents a case study of the recent EU treaty revision process, culminating in the Treaty of Lisbon. In so doing, it enables a deeper understanding of recent policy developments

Successful Flash-Cooling of Xenon Derivatized Myoglobin Crystals

This paper demonstrates for the first time a method for preparing cryocooled xenon-derivatized protein crystals. The method is based upon the hypothesis and subsequent observation that the diffusion of a xenon atom from a tight binding site following depressurization occurs on a timescale of minutes. We have observed significant changes in diffraction intensities from myoglobin crystals for up to 5 min following depressurization from 1 MPa of xenon. In accordance with this observation, a xenon-derivatized myoglobin crystal was cryocooled at ~95 K within 20 s of complete depressurization. A crystallographic data set was then collected to 2.0 Å resolution and isomorphous and anomalous difference Patterson maps revealed the presence of a well ordered xenon site with an occupancy of approximately 0.5. Phasing statistics for this site were of good quality and demonstrate the practicality of this method. The ability to cryocool xenon-derivatized crystals will make this heavy-atom substitution method even more useful for single-isomorphous-replacement and multiple-isomorphous-replacement phasing of macromolecules

Analytic Inversion of Emission Lines of Arbitrary Optical Depth for the Structure of Supernova Ejecta

We derive a method for inverting emission line profiles formed in supernova ejecta. The derivation assumes spherical symmetry and homologous expansion (i.e., $v(r) \propto r$), is analytic, and even takes account of occultation by a pseudo-photosphere. Previous inversion methods have been developed which are restricted to optically thin lines, but the particular case of homologous expansion permits an analytic result for lines of {\it arbitrary} optical depth. In fact, we show that the quantity that is generically retrieved is the run of line intensity $I_\lambda$ with radius in the ejecta. This result is quite general, and so could be applied to resonance lines, recombination lines, etc. As a specific example, we show how to derive the run of (Sobolev) optical depth $\tau_\lambda$ with radius in the case of a pure resonance scattering emission line.Comment: 6 pages, no figures, to appear in Astrophysical Journal Letters, requires aaspp4.sty to late

INTEGRAL and XMM-Newton Spectral Studies of NGC 4388

We present first INTEGRAL and XMM-Newton observations of a Seyfert galaxy, the type 2 AGN NGC 4388. Several INTEGRAL observations performed in 2003 allow us to study the spectrum in the 20 - 300 keV range. In addition two XMM-Newton observations give detailed insight into the 0.2 - 10 keV emission. The measurements presented here and comparison with previous observations by BeppoSAX, SIGMA and CGRO/OSSE show that the overall spectrum from soft X-rays up to the gamma-rays can be described by a highly absorbed (N_H = 2.7e23 1/cm^2) and variable non-thermal component in addition to constant non-absorbed thermal emission (T = 0.8 keV) of low abundance (7% solar), plus a constant Fe K-alpha and K-beta line. The hard X-ray component is well described by a simple power law with a mean photon index of 1.7. During the INTEGRAL observations the 20 - 100 keV flux increased by a factor of 1.4. The analysis of XMM-Newton data implies that the emission below 3 keV is decoupled from the AGN and probably due to extended emission as seen in Chandra observations. The constant iron line emission is apparently also decoupled from the direct emission of the central engine and likely to be generated in the obscuring material, e.g. in the molecular torus.Comment: 11 pages, 5 figures, accepted for publication in Ap

Describing protein conformational ensembles: beyond static snapshots

Protein molecules are not static but are in varying degrees of motion. Of course, the breadth of structural arrangements in an ensemble will vary tremendously. Some proteins are like ‘rocks’ and are very tightly constrained in terms of deviations of their coordinates from their averages. Others are ‘writhing snakes’, with little recognized persistent structure, and then there is everything in between. Through the work of many, there is an increasing awareness of the role of dynamics in the biological function of proteins, and new computational and experimental methods are allowing us to make these connections. A personal perspective on the state of affairs is offered with examples primarily from the author's own work

Analysis of the Type IIn Supernova 1998S: Effects of Circumstellar Interaction on Observed Spectra

We present spectral analysis of early observations of the Type IIn supernova 1998S using the general non-local thermodynamic equilibrium atmosphere code \tt PHOENIX}. We model both the underlying supernova spectrum and the overlying circumstellar interaction region and produce spectra in good agreement with observations. The early spectra are well fit by lines produced primarily in the circumstellar region itself, and later spectra are due primarily to the supernova ejecta. Intermediate spectra are affected by both regions. A mass-loss rate of order $\dot M \sim 0.0001-0.001$\msol yr$^{-1}$ is inferred for a wind speed of 100-1000 \kmps. We discuss how future self-consistent models will better clarify the underlying progenitor structure.Comment: to appear in ApJ, 2001, 54

Limits from the Hubble Space Telescope on a Point Source in SN 1987A

We observed supernova 1987A (SN 1987A) with the Space Telescope Imaging Spectrograph (STIS) on the Hubble Space Telescope (HST) in 1999 September, and again with the Advanced Camera for Surveys (ACS) on the HST in 2003 November. No point source is observed in the remnant. We obtain a limiting flux of F_opt < 1.6 x 10^{-14} ergs/s/cm^2 in the wavelength range 2900-9650 Angstroms for any continuum emitter at the center of the supernova remnant (SNR). It is likely that the SNR contains opaque dust that absorbs UV and optical emission, resulting in an attenuation of ~35% due to dust absorption in the SNR. Taking into account dust absorption in the remnant, we find a limit of L_opt < 8 x 10^{33} ergs/s. We compare this upper bound with empirical evidence from point sources in other supernova remnants, and with theoretical models for possible compact sources. Bright young pulsars such as Kes 75 or the Crab pulsar are excluded by optical and X-ray limits on SN 1987A. Of the young pulsars known to be associated with SNRs, those with ages < 5000 years are all too bright in X-rays to be compatible with the limits on SN 1987A. Examining theoretical models for accretion onto a compact object, we find that spherical accretion onto a neutron star is firmly ruled out, and that spherical accretion onto a black hole is possible only if there is a larger amount of dust absorption in the remnant than predicted. In the case of thin-disk accretion, our flux limit requires a small disk, no larger than 10^{10} cm, with an accretion rate no more than 0.3 times the Eddington accretion rate. Possible ways to hide a surviving compact object include the removal of all surrounding material at early times by a photon-driven wind, a small accretion disk, or very high levels of dust absorption in the remnant.Comment: 40 pages, 5 figures. AAStex. Accepted, ApJ 04/28/200

Moving beyond static snapshots: Protein dynamics and the Protein Data Bank

Proteins are the molecular machines of living systems. Their dynamics are an intrinsic part of their evolutionary selection in carrying out their biological functions. Although the dynamics are more difficult to observe than a static, average structure, we are beginning to observe these dynamics and form sound mechanistic connections between structure, dynamics, and function. This progress is highlighted in case studies from myoglobin and adenylate kinase to the ribosome and molecular motors where these molecules are being probed with a multitude of techniques across many timescales. New approaches to time-resolved crystallography are allowing simple “movies” to be taken of proteins in action, and new methods of mapping the variations in cryo-electron microscopy are emerging to reveal a more complete description of life’s machines. The results of these new methods are aided in their dissemination by continual improvements in curation and distribution by the Protein Data Bank and their partners around the world