Quality of life among people with mental illness attending a psychiatric outpatient clinic in Ethiopia: a structural equation model

BackgroundMental illness is one of the most severe, chronic, and disabling public health problems that affects patients’ Quality of life (QoL). Improving the QoL for people with mental illness is one of the most critical steps in stopping disease progression and avoiding complications of mental illness. Therefore, we aimed to assess the QoL and its determinants in patients with mental illness in outpatient clinics in Northwest Ethiopia in 2023.MethodsA facility-based cross-sectional study was conducted among people with mental illness in an outpatient clinic in Ethiopia. The sampling interval was decided by dividing the total study participants who had a follow-up appointment during the data collection period (2400), by the total sample size 638, with the starting point selected by lottery method. The interviewer-administered WHOQOL BREF-26 tool was used to measure the quality of life (QoL) of people with mental illness. The domains of QoL were identified, and indirect and direct effects of variables were calculated using structural equation modelling with SPSS-28 and Amos-28 software. A p-value of < 0.05 and a 95% CI were used to evaluate statistical significance.ResultsA total of 636 (99.7%) participants agreed to participate and completed the data collection. The mean score of overall QoL of people with mental illness in the outpatient clinic was 49.6 ± 10 Sd. The highest QoL was found in the physical health domain (50.67 ± 9.5 Sd), and the lowest mean QoL was found in the psychological health domain (48.41 ± 10 Sd). Rural residence, drug nonadherence, suicidal ideation, not getting counselling, moderate or severe subjective severity, family does not participate in patient care and a family history of mental illness had an indirect negative effect on QoL. Alcohol use and psychological health domain had direct positive effect on QoL. Furthermore, objective severity of illness, having low self-esteem, and having history of mental illness in the family had both direct and indirect effect on QoL. Furthermore, sociodemographic factors (rural residence, illiterate educational status, not married marital status), social support-related factors (poor self-esteem, family not participating in patient care), substance use factors (alcohol use, tobacco use) and clinical factors (high objective and subjective severity of illness, not getting counselling, suicidal ideation, higher number of episodes, comorbid illness, family history of mental illness, poor drug adherence) directly and indirectly affected QoL.ConclusionsIn this study, the QoL of people with mental illness was poor, with the psychological health domain the most affected. Sociodemographic factors, social support-related factors, drug use factors, and clinical factors, directly and indirectly affected QoL through the mediator variables of physical health domains, psychological health domains, social relation health domains, and environmental health domains. In order to improve the QoL of people with mental illnesses, we recommend that emphasis be given to addressing the QoL of those with mental illness, including the development of policy and practice responses that address the above identified factors

Mental health service satisfaction among adults with mental illness attending a psychiatric outpatient clinic: a cross-sectional study

BackgroundPatient satisfaction with services is both a direct and indirect indicator of healthcare quality. It influences healthcare outcomes, patient retention, and the likelihood of medical malpractice claims. However, there is limited evidence on patient satisfaction with mental health services in Africa. Therefore, we aimed to assess mental health service satisfaction and its determinants in adult patients with mental illness in an outpatient clinic in Northwest Ethiopia.MethodsA hospital-based cross-sectional study was conducted from October to March 2023. Participants were selected using systematic random sampling with a sample interval of three, resulting in a total sample size of 638 invited to participate. Service satisfaction was measured using the interviewer-administered Client Satisfaction Questionnaire-8 (CSQ-8). Data entry, coding, and analysis were performed using SPSS-28. To examine the association of sociodemographic, clinical, social support, and substance use factors, bivariate and multivariate logistic regression analyses were applied. Statistical significance was declared at a p-value of <0.05 and 95% CI.ResultsThe rate of low mental health service satisfaction among people with mental illness in this study was 24.7%. According to our multivariate logistic regression analysis, people with urban residence 1.77 (1.15, 2.72), poor self-reported health 3.62(1.97, 6.67), having episodic illness ≥2/yr. 0.48 (0.32, 0.74), having relapse 1.75 (1.12, 2.73), and poor drug adherence 2.28 (1.20, 4.35) were more likely to have low mental health service satisfaction than their counterparts.Conclusions and recommendationOne-quarter of patients with mental illness in the outpatient clinic reported low satisfaction with mental health services. Factors associated with lower satisfaction included urban residency, episodic illness, relapse, poor self-reported health, and poor drug adherence. To enhance patient satisfaction, the clinic should prioritize targeted support for patients facing these challenges

Prevalence and Associated Factors of Depression among PLHIV in Ethiopia: Systematic Review and Meta-Analysis, 2017

Background. Depression is a substantial contributor to the global burden of disease and affects people in all communities across the globe. Depression is the most common psychiatric problem associated with HIV/AIDS and half of all PLWHIV with depression go underdiagnosed and untreated. Psychiatric complications of HIVAIDS delay mental health services in less affluent countries. However, there is lack of study with regard to the pooled estimation prevalence of depression in PLWHIV in Ethiopia. Objectives. The aim of this systematic review and meta-analysis is to summarize the most current available evidence from 2010 to March 2017 among adult PLWHIV in Ethiopia. Methods. The team explored multiple databases searching methods including MEDLINE/PubMed, PsycINFO, Google Advance Scholar, and Google Scholar to find studies published with the data on the prevalence of depression among PLWHIV. We searched 150 research articles; of these 143 articles were excluded. Subsequently, thirteen articles were used for synthesis prevalence and four studies were included in the synthesis effect of sex on depression among PLWHIV. Results. The total of pooled estimated prevalence of depression in PLWHIV was 36.65. Estimated prevalence of depression in three studies by using CES-D was 31.19% and in six studies by using PHQ-9 was 37.91%. The remaining four studies used a single tool: Kessler-6 Scale (15.5%), HADS (41.2%), HDSQ (43.9%), and BDI (55.8%). Factors such as age, marital status, living alone, poor medication adherence, poor social support, clinical stages II and III of HIV, stigma, income, and occupation were significantly associated with depression. Conclusions and Recommendation. The pooled estimate prevalence of depression among PLWHIV was higher than that in the general population. It is better to offer special attention to these populations

Prevalence and correlates of alcohol use disorders among bipolar patients at Amanuel Mental Specialized Hospital, Addis Ababa (Ethiopia): A cross-sectional institution based study

At this time, alcohol use is increasing in African countries. The prevalence of alcohol use disorders (AUDs) remains unknown in patients with psychiatric disorders. This study aimed to assess the prevalence of AUDs among individuals with bipolar disorder in the outpatient department at Amanuel Mental Specialized Hospital. An institution-based cross sectional study was conducted among 412 bipolar patients attending the outpatient department at Amanuel Mental Specialized Hospital from May – July 2015.Participants were selected using a systematic random sampling technique. Semi-structured questionnaires were used to collect socio-demographic and clinical data. Alcohol use disorder was measured using the Alcohol Use Disorders Identification Test (AUDIT-10). Binary logistic regression analysis was performed. The prevalence of alcohol use disorder was found to be 24.5%. Those affected were predominantly female (58.5%). Being18-29 years of age(AOR=3.86, 95% CI: 1.34, 11.29), being 30-44 years of age (AOR=4.99, 95%CI: 1.85, 13.46), being unable to read and write (AOR=5.58, 95%CI: 2.026, 13.650), having a secondary education (AOR=3.198, 95%CI: 1.149, 8.906), being a farmer (AOR=4.54, 95%CI: 1.67, 12.32), being employed by the government (AOR=3.53, 95%CI: 1.36, 4.15), being a day labourer (AOR=3.5, 95%CI: 1.14, 10.77), use of other substances during past 12 months (AOR=2.06, 95%CI: 1.06, 3.99), having a family history of alcohol use (AOR=2.18, 95%CI: 1.29, 3.68), having discontinued medication (AOR=2.78, 95%CI: 1.52, 5.07), having suicidal thoughts (AOR=4.56, 95%CI: 2.43, 8.54), and having attempted suicide (AOR=5.67, 95%CI: 3.27, 9.81) were statistically significant to alcohol use disorder using multivariate logistic analysis. The prevalence of co-morbid alcohol use disorder was high. This finding suggests that screening for risky alcohol use should be integrated into routine hospital outpatient care. Further, preventive measures against alcohol use disorder should be established

Prevalence of post-traumatic stress disorder and associated factors among police officers in Central Gondar Zone, North West Ethiopia, 2023: institutional-based cross-sectional study

BackgroundPost-traumatic stress disorder (PTSD) is a psychiatric disorder that follows exposure to a traumatic or stressful life event. Police officers are exposed to a number of traumatic events that put them at risk of developing post-traumatic stress disorder. Previous studies have found the prevalence of post-traumatic stress disorder among police officers to be varied and inclusive. However, in Ethiopia, little is known about the prevalence of post-traumatic stress disorder and associated factors among police officers. Therefore, assessing the prevalence and associated factors of post-traumatic stress disorder among police officers might have a plausible role in future investigations.ObjectiveThe aim of this study was to assess the prevalence of post-traumatic stress disorder and associated factors among police officers in Central Gondar Zone, North West Ethiopia, 2023.MethodsAn institutional-based cross-sectional study was conducted in Central Gondar Zone by using self-administered and semi-structured questionnaires. A multi-stage cluster sampling technique was employed to select a sample of 634 participants. Post-traumatic stress disorder was assessed using the PTSD Checklist DSM-5. The collected data were coded and entered using Epi data Software version 4.6.02 and then exported to STATA version 14 for analysis. Bivariable and multivariable logistic regression analyses were done to identify factors associated with post-traumatic stress disorder. Statistically significant results were declared at a 95% confidence interval (CI) of a p-value less than 0.05.ResultsThe prevalence of post-traumatic stress disorder was found to be 15.2%, with a 95% CI of 12.5% to 18.3%. In the multivariate analysis, female (AOR = 3.36, 95% CI 1.95–5.78), being directly exposed to traumatic events (AOR = 2.01, 95% CI 1.16–3.48), current alcohol use (AOR = 2.90, 95% CI 1.65–5.12), and having poor social support (AOR = 4.25, 95% CI 1.58–11.36) were factors significantly associated with post-traumatic stress disorder.ConclusionAccording to this study, police officers suffered from a significant burden of post-traumatic stress disorder. Female sex, police personnel directly exposed to traumatic events, current alcohol users, and those who had poor social support were found to be strongly associated with post-traumatic stress disorder. Therefore, early detection and intervention are crucial to mitigating the overall problem

Post-traumatic stress disorder in the Ethiopian population dwelling in war-affected communities: a systematic review and meta-analysis

BackgroundPost-traumatic stress disorder (PTSD) is a significant mental health concern globally, particularly prevalent in populations exposed to war and conflict. This systematic review and meta-analysis aim to examine the prevalence and factors associated with PTSD among the Ethiopian population residing in war-affected communities.MethodsThe review was reported according to the PRISMA guidelines. Related eligible published articles were searched in electronic online databases such as PubMed, Scopus, Web of Science, MEDLINE/PubMed, Scopus, Embase, Science Direct, Web of Science, Google Scholar, and Google, which reported the prevalence and risk factors of PTSD among people dwelling in the war-affected area until January 2024. The relevant data was extracted using a Microsoft Excel spreadsheet. The meta-analysis was conducted using STATA version 11. The estimated pooled prevalence and risk factors were estimated using a random effect model. The potential risk of publication bias was checked using a funnel plot and Egger’s statistical test.ResultsA total of nine published studies with 6107 participants were analyzed in this meta-analysis. The estimated pooled prevalence of PTSD among people living in war-affected areas was 48.4%, with a 95% CI (37.1, 59.8). This study found a higher prevalence of PTSD among women than men. Being female (OR= 2.2, 95% CI: 1.2, 4.3), witnessing a murder of a loved one (OR= 3.0, 95% CI: 1.2, 7.5), depression symptoms (OR= 2.8, 95% CI: 1.4, 5.6), and anxiety symptoms (OR= 3.4, 95% CI: 1.4, 8.0), a close family member killed or seriously injured (OR= 3.1, 95% CI: 1.2, 7.7), a moderate and high perceived threat to life (OR= 3.4, 95% CI: 1.3, 9.1), and poor social support (OR= 4.4, 95% CI: 1.1, 18.7) were associated with post-traumatic stress disorder.ConclusionThe result of this study shows the high prevalence rate of PTSD in people living in war-affected areas. disparities in PTSD prevalence, with women being at higher risk, and identified risk factors were witnessing the murder of a loved one, experiencing depression and anxiety, and perceived threat to life. Addressing PTSD in war-affected communities requires comprehensive interventions that consider both individual and contextual factors.Systematic review registrationwww.crd.york.ac.uk/PROSPERO/, identifier CRD42024501384

National prevalence and associated factors of khat chewing among students in Ethiopia: A protocol for a systematic review and meta-analysis

The existing prevalence of khat chewing among university students ranges from 23.1% to 74.1%. Its impact affected students mentally, physically, economically and their social interaction. The aim of this systematic review and meta-analysis will be to determine the prevalence of khat chewing and associated factors among students in Ethiopia and to help guide policy makers in the decision-making process. A complete systematic review and meta-analysis of published studies on the prevalence of khat chewing and associated factors in Ethiopia will be conducted. A computerized internet search using Medline/PubMed, Google Scholar and EMBASE databases and reference lists of previous prevalence studies and full search strategy and cross-checking of reference lists of published peerreviewed articles will be conducted to identify all cross-sectional and cohort studies published in English. We will use the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) statement for reporting. Pooled estimated effect of prevalence of khat chewing and associated factors will be analyzed using the random effects meta-analysis (random effects model) and (with 95% CI) will be measured. The underlying work is based on systematic reviews of published data and thus do not require ethical review approval. The results of the systematic review will be disseminated in different conferences, seminars and published in a reputable international reviewed journal. A complete systematic review and meta-analysis of published studies on the prevalence of khat chewing and associated factors in Ethiopia will be conducted. All observational studies of (cross-sectional, cohort, case control) and randomized controlled trials will be included. A widespread range of studies and settings will be included

Risky sexual behaviors of schizophrenic patients: a single center study in Ethiopia, 2018

Abstract Objective Identify factors related to risky sexual behavior can facilitate health care providers to approach programs that improve quality of services provided to the patient service. The aim of study to assess the prevalence of risky sexual behaviors and associated factors among schizophrenia patient at Amanuel Mental specialized hospital, Addis Ababa, Ethiopia, 2019. Result A total of four hundred twenty-nine participants were interviewed with a response rate of 97.05%. The prevalence of risky sexual behavior was 39.4% (95% CI 34.3, 43.6). In the multivariate logistic regression, being male sex (AOR = 3.78 (1.94, 7.38)), patients in age group between 18 and 24 (AOR = 4.85 (1.73, 13.6)), current use of alcohol (AOR = 1.86 (1.049, 3.32)), place of residence (AOR = 6.22 (2.98, 12.98)), positive symptom (AOR = 3.01 (1.55, 5.84)) were associated with risky sexual behavior. </jats:sec

Prevalence of perceived stigma and associated factors among primary caregivers of children and adolescents with mental illness, Addis Ababa, Ethiopia: Cross-sectional study

Background Mental illness exposes persons to stigma and this stigma also affects family caregivers of persons with mental illness. The objective of the study was to assess the prevalence of perceived stigma and associated factors among primary caregivers of children and adolescents with mental illness, Addis Ababa, Ethiopia. Methods A cross-sectional study design and systematic random sampling technique were used to recruit 408 participants at St. Paul’s Hospital Millennium Medical College and Yekatit-12 Hospital Medical College, Addis Ababa, Ethiopia. We collected the data by face-to-face interview. Devaluation of Consumer Families Scale was used to measure perceived stigma. Patient Health Questionnaire-9 and Oslo-3 social support scale were the instruments used to assess the factors. Coded variables were entered into Epidata V.3.1 and exported to SPSS V.21 for analysis. Binary logistic regression was used for analysis. Result A total of 408 participants were interviewed, with a response rate of 96.5%. The magnitude of perceived stigma was 38.5% with 95% CI (33.6-43.1). Majority (68.6%) of the respondents were female. In the multivariate logistic regression, being mother (AOR = 2.8, 95% CI: 1.59, 4.91), absence of other caregiver (AOR = 2.0, 95% CI: 1.15, 3.49), poor social support (AOR = 3.9, 95% CI: 1.59, 6.13), and symptoms of depression (AOR = 2.9, 95% CI: 1.88, 3.65) were factors significantly associated with perceived stigma. Conclusion The prevalence of perceived stigma among primary caregivers of children and adolescents with mental illness was high. Being mother, absence of other caregiver, poor social support, and symptoms of depression were factors significantly associated with perceived stigma. </jats:sec