The body in the library: adventures in realism

This essay looks at two aspects of the virtual ‘material world’ of realist fiction: objects encountered by the protagonist and the latter’s body. Taking from Sartre two angles on the realist pact by which readers agree to lend their bodies, feelings, and experiences to the otherwise ‘languishing signs’ of the text, it goes on to examine two sets of first-person fictions published between 1902 and 1956 — first, four modernist texts in which banal objects defy and then gratify the protagonist, who ends up ready and almost able to write; and, second, three novels in which the body of the protagonist is indeterminate in its sex, gender, or sexuality. In each of these cases, how do we as readers make texts work for us as ‘an adventure of the body’

Structure and genome of severe acute respiratory syndrome coronavirus 2

SARS-CoV-2 is a novel coronavirus responsible for the current COVID-19 pandemic. It is the seventh coronavirus known to infect humans (the previous human coronaviruses are HCoV-OC43, HCoV-229E, HCoV-HKU1, HCoV-NL63, SARS-CoV and MERS-CoV) and the third human coronavirus known to cause severe illness in human after SARS-CoV and MERS-CoV. These three coronaviruses have caused three different severe respiratory diseases outbreaks within the last two decades: SARS in 2002-2003, MERS in 2012 and COVID-19 in 2020. The aim of this review was to summarize information on the genome and structure of SARS-CoV-2.    SARS-CoV-2 is an enveloped positive-sense single-stranded RNA virus with a crown-like appearance due to the presence of spike glycoprotein on the envelope. The nonsegmented genome of SARS-CoV-2 of approximately 30kb encodes two large polyproteins, four main structural proteins namely spike, membrane, envelope and nucleocapsid proteins as well as several accessory proteins. Analysis of SARS-CoV-2 genome shows that it is highly related to coronavirus from the bat (96%), pangolin (91%) and SARS-CoV (80%). Variants of SARS-CoV-2 have evolved continuously as a result of genetic mutations and are circulating worldwide. These variants have varying degrees of transmissibility, disease severity, susceptibility to therapeutics and detection by diagnostic tools. Understanding the structure and genome of SARS-CoV-2 is important in the control, management, diagnosis and treatment of COVID-19 as well as vaccine development

The Carmaux Strike

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Effects of Electronic Devices and Social Media in the Prospects of Australian Higher Education, Teaching and Learning [Efectos de los dispositivos electrónicos y las redes sociales en las perspectivas de la educación superior, la enseñanza y el aprendizaje en Australia]

Abstract: This paper presents a comprehensive analysis of the effects of electronic devices and social media in the prospects of Australian higher education, teaching and learning. The purpose of this research is to discover teaching and learning when electronic devices and social media are implemented and integrated in Australian educaN2o3e4liaztion. This paper mainly has used secondary research data and methods to provide a broad investigation of teaching and learning with electronic devices and the roles social media play. The research is subject to academic journal articles, project reports, media articles, corporation based documents and other appropriate information. The study found that electronic devices and social media present both opportunities and challenges to higher education. In addition, they offer advantages for student learning and frustrations from learning with electronic devices. One of the most important advantages is the ability to access information quickly and conveniently such as accessing course contents such a discussion boards, course readings, and video clips they need to watch for class on their mobile devices. In addition, they use their devices to upload and post content to course sites. Overall, the students found using mobile devices very convenient. Also constant connectivity among the devices helps the students to communicate with fellow classmates and the teachers. Social media such as Face book, Twitter have allowed students to share their thoughts immediately with their classmates within the course of their everyday lives. Finally the review found that though Australian students have considered electronic devices helpful, frustrations from learning with the devices are obvious which include anti-technology instructors in other classes, e-device challenges, and devices as a distraction.Keywords: Electronic Devices; Social Media; Higher Education; Teaching & Learning; Australia. Resumen:Este artículo presenta un análisis exhaustivo de los efectos de los dispositivos electrónicos y las redes sociales en las perspectivas de la educación superior, la enseñanza y el aprendizaje australianos. El propósito de esta investigación es descubrir la enseñanza y el aprendizaje cuando los dispositivos electrónicos y las redes sociales se implementan e integran en la educación australiana. Este documento ha utilizado principalmente datos y métodos de investigación secundaria para proporcionar una amplia investigación de la enseñanza y el aprendizaje con dispositivos electrónicos y los roles que desempeñan las redes sociales. La investigación está basada en artículos de revistas académicas, informes de proyectos, artículos de medios, documentos corporativos y otra información apropiada. El estudio mostró que los dispositivos electrónicos y las redes sociales presentan oportunidades y desafíos para la educación superior. Además, ofrecen ventajas para el aprendizaje de los alumnos y frustraciones derivadas del aprendizaje con dispositivos electrónicos. Una de las ventajas más importantes es la capacidad de acceder a la información de manera rápida y cómoda, como acceder a los contenidos del curso, tales como paneles de discusión, lecturas de cursos y videoclips que deben ser vistos por la clase en sus dispositivos móviles. Además, utilizan sus dispositivos para cargar y publicar contenido en los sitios del curso. En general, los estudiantes encontraron que usar dispositivos móviles es muy conveniente. También la conectividad constante entre los dispositivos ayuda a los estudiantes a comunicarse con sus compañeros de clase y los profesores. Los medios sociales como Facebook o Twitter han permitido a los estudiantes compartir sus pensamientos de inmediato con sus compañeros de clase en el transcurso de su vida cotidiana. Finalmente, la revisión encontró que aunque los estudiantes australianos han considerado útiles los dispositivos electrónicos, las frustraciones por aprender con los dispositivos son obvias, lo que incluye a los instructores antitecnología en otras clases, los desafíos de dispositivos electrónicos y los dispositivos como una distracción.Palabras clave: dispositivos electrónicos; Medios de comunicación social; Educación Superior; Enseñanza y aprendizaje; Australia

Optimization of Forced Degradation Using Experimental Design and Development of a Stability-Indicating Liquid Chromatographic Assay Method for Rebamipide in Bulk and Tablet Dosage Form

A novel stability-indicating RP-HPLC assay method was developed and validated for quantitative determination of rebamipide in bulk and tablet dosage form. Rebamipide (drug and drug product) solutions were exposed to acid and alkali hydrolysis, thermal stress, oxidation by hydrogen peroxide and photodegradation. Experimental design has been used during forced degradation to determine significant factors responsible for degradation and to obtain optimal degradation conditions. In addition, acid and alkali hydrolysis was performed using a microwave oven. The chromatographic method employed the HiQ sil C-18HS (250 × 4.6 mm; 5 μm) column with mobile phase consisting of 0.02 M potassium phosphate (pH adjusted to 6.8) and methanol (40:60, v/v) and the detection was performed at 230 nm. The procedure was validated for specificity, linearity, accuracy, precision and robustness. There was no interference observed of excipients and degradation products in the determination of the active pharmaceutical ingredient. The method showed good accuracy and precision (intra and inter day) and the response was linear in a range from 0.5 to 5 μg mL−1. The method was found to be simple and fast with less trial and error experimentation by making use of experimental design. Also, it proved that microwave energy can be used to expedite hydrolysis of rebamipide

'Against the World': Michael Field, female marriage and the aura of amateurism'

This article considers the case of Katherine Bradley and Edith Cooper, an aunt and niece who lived and wrote together as ‘Michael Field’ in the fin-de-siècle Aesthetic movement. Bradley’s bold statement that she and Cooper were ‘closer married’ than the Brownings forms the basis for a discussion of their partnership in terms of a ‘female marriage’, a union that is reflected, as I will argue, in the pages of their writings. However, Michael Field’s exclusively collaborative output, though extensive, was no guarantee for success. On the contrary, their case illustrates the notion, valid for most products of co-authorship, that the jointly written work is always surrounded by an aura of amateurism. Since collaboration defied the ingrained notion of the author as the solitary producer of his or her work, critics and readers have time and again attempted to ‘parse’ the collaboration by dissecting the co-authored work into its constituent halves, a treatment that the Fields too failed to escape

Developing the EBS Management Model to Assist SMEs to Evaluate E-Commerce Success

In the literature, a lack of strong consensus or well-known theoretical research framework exists to defining and evaluating e-commerce success among small to medium enterprises (SMEs). Exploring more effective methods to describe and evaluate e-commerce success becomes a challenging task. This research seeks to help fill the gap by proposing a new model to evaluate e-commerce success from a business perspective. This measure has been termed e-commerce business satisfaction (EBS). A total of 2401 surveys were successfully sent to SMEs. The usable response rate for the surveys was 7.54%. Principal component analysis with varimax rotation method was then adopted within the factor analysis. Using the 15 critical success factors (CSFs) obtained from previous research as a foundation, an EBS management model was finally simply developed to assist SMEs business managers in effectively adopting e-commerce systems or evaluating e-commerce success, which was categorised into five components including Marketing, Management Support and Customer Acceptance, Website Effectiveness and Cost, Managing Change and Knowledge and Skills. Further research is needed to determine the weighting of each CSF so that a yardstick measurement method might be further developed to assist SMEs in adopting e-commerce successfully