Preliminary Design of Reactive Distillation Columns

A procedure that combines feasibility analysis, synthesis and design of reactive distillation columns is introduced. The main interest of this methodology lies on a progressive introduction of the process complexity. From minimal information concerning the physicochemical properties of the system, three steps lead to the design of the unit and the specification of its operating conditions. Most of the methodology exploits and enriches approaches found in the literature. Each step is described and our contribution is underlined. Its application is currently limited to equilibrium reactive systems where degree of freedom is equal to 2 or less than 2. This methodology which provides a reliable initialization point for the optimization of the process has been applied with success to different synthesis. The production of methyl-tert-butyl-ether (MTBE) and methyl acetate are presented as examples

Providers and women's perspectives on person-centered maternity care: a mixed methods study in Kenya.

BackgroundGlobally, there has been increasing attention to women's experiences of care and calls for a person-centered care approach. At the heart of this approach is the patient-provider relationship. It is necessary to examine the extent to which providers and women agree on the care that is provided and received. Studies have found that incongruence between women's and providers' perceptions may negatively impact women's compliance, satisfaction, and future use of health facilities. However, there are no studies that examine patient and provider perspectives on person-centered care.MethodsTo fill this gap in the literature, we use cross-sectional data of 531 women and 33 providers in seven government health facilities in Kenya to assess concordance and discordance in person-centered care measures. Additionally, we analyze 41 in-depth interviews with providers from three of these facilities to examine why differences in reporting may occur. Descriptive statistical methods were used to measure the magnitude of differences between reports of women and reports of providers. Thematic analyses were conducted for provider surveys.ResultsOur findings suggest high discordance between women and providers' perspectives in regard to person-centered care experiences. On average, women reported lower levels of person-centered care compared to providers, including low respectful and dignified care, communication and autonomy, and supportive care. Providers were more likely to report higher rates of poor health facility environment such as having sufficient staff. We summarize the overarching reasons for the divergence in women and provider reports as: 1) different understanding or interpretation of person-centered care behaviors, and 2) different expectations, norms or values of provider behaviors. Providers rationalized abuse towards women, did not allow a companion of choice, and blamed women for poor patient-provider communication. Women lacked assurance in privacy and confidentiality, and faced challenges related to the health facility environment. Providers attributed poor person-centered care to both individual and facility/systemic factors.ConclusionsImplications of this study suggests that providers should be trained on person-centered care approaches and women should be counseled on understanding patient rights and how to communicate with health professionals

A statistical model for application of maneuver flight loads data to structural design criteria

Statistical model for application of maneuver flight loads data to structural design dat

New possibilities arise for studies of hybridization: SNP-based markers for the multi-species Daphnia longispina complex derived from transcriptome data

In order to trace community dynamics and reticulate evolution in hybrid species complexes, long-term comparative studies of natural populations are necessary. Such studies require the development of tools for fine-scale genetic analyses. In the present study, we developed species-diagnostic SNP-based markers for hybridizing freshwater crustaceans: the multispecies Daphnia longispina complex. Specifically, we took advantage of transcriptome data from a key species of this hybrid complex, the annotated genome of a related Daphnia species and well-defined reference genotypes from three parental species. Altogether eleven nuclear loci with several species-specific SNP sites were identified in sequence alignments of these reference genotypes from three parental species and their interspecific hybrids. A PCR-RFLP assay was developed for cost-efficient large population screening by SNP-based genotyping. Taxon assignment by RFLP patterns was nearly perfectly concordant with microsatellite genotyping across several screened populations from Europe. Finally, we were able to amplify two short regions of these loci in formaldehyde-preserved samples dating back to the year 1960. The species-specific SNP-based markers developed here provide valuable tools to study hybridization over time, including the long-term impact of various environmental factors on hybridization and biodiversity changes. SNP-based genotyping will finally allow eco-evolutionary dynamics to be revealed at different time scale

Participant accuracy and impact of biofeedback on a skilled swallowing task

Biofeedback is as a visual way to self-assess muscle contraction, particularly during rehabilitative exercises. Speech language pathologists and otolaryngologists have investigated the use of visual biofeedback in swallowing therapy, especially for volitional swallowing rehabilitative exercises such as the effortful swallow, which requires the patient to maximally swallow with all their strength. In contrast to the effortful swallow, “effortful skilled swallowing” is the ability to swallow with a specific and precise amount of effort, which is an emerging topic in dysphagia research. Dysphagia, also known as disordered swallowing, can be an organic congenital disorder treated via feeding tubes, or an acquired disorder as a result of a old age, traumatic injury, intubation, neurodegenerative diseases, or a stroke, among other etiologies. In the United States, one quarter of the population will struggle with swallowing at some point. It plagues 13-15% of acute care hospital patients, 30-35% of those in rehabilitation settings, and 40-50% of individuals living in nursing homes. This study examined the use of skilled swallowing targets in healthy, non-dysphagic participants, concentrating on examining the following: 1) the participants’ ability to differentiate and execute different skill level targets, 2) the effectiveness of visual biofeedback at improving participant’s accuracy at skilled swallowing tasks, and 3) participant accuracy over time, over the course of 30 successive swallows. Data was collected from eight participants, seven of which were used in this study. Participants were trained and then randomly instructed to swallow at three different effort levels: 50%, 75%, and 100%. They were then evaluated to see how closely they swallowed compared to the target effort level. This was defined as the level of accuracy. Accuracy was measured by surface electromyography (sEMG) electrodes placed on the anterior submental region of the neck. Visual biofeedback of their EMG signal was provided to the participant for fifteen random swallows of the thirty swallows in each experimental exercise. The results indicate that participants are able to modulate their swallowing effort to approximate three different effort levels, but that biofeedback did not affect participants’ accuracy. Additionally, participants’ accuracy in achieving skilled swallow targets did not change over the course of 30 swallows. These results indicate that swallowing effort can be modulated and used as a skilled task during treatment. Biofeedback, while useful in training a swallowing task, may not be needed during every trial to ensure accuracy. Finally, in these healthy participants, there did not seem to be an effect of boredom or fatigue while successively performing 30 skilled swallow tasks over the course of 22 minutes. It is not known if these results are generalizable to an older, dysphagic population

Continuous positive airway pressure for children with undifferentiated respiratory distress in Ghana: an open-label,cluster, crossover trial

Background In low-income and middle-income countries, invasive mechanical ventilation is often not available for children at risk of death from respiratory failure. We aimed to determine if continuous positive airway pressure (CPAP), a form of non-invasive ventilation, decreases all-cause mortality in children with undifferentiated respiratory distress in Ghana. Methods This open-label, cluster, crossover trial was done in two Ghanaian non-tertiary hospitals where invasive mechanical ventilation is not routinely available. Eligible participants were children aged from 1 month to 5 years with a respiratory rate of more than 50 breaths per min in children 1–12 months old, or more than 40 breaths per min in children older than 12 months, and use of accessory muscles or nasal flaring. CPAP machines were allocated to one hospital during each study block, while the other hospital served as the control site. The initial intervention site was randomly chosen using a coin toss. 5 cm of water pressure was delivered via CPAP nasal prongs. The primary outcome measure was all-cause mortality rate at 2 weeks after enrolment in patients for whom data were available after 2 weeks. We also did post-hoc regression analysis and subgroup analysis of children by malaria status, oxygen saturation, and age. This study is registered with ClinicalTrials.gov, number NCT01839474. Findings Between Jan 20, 2014, and Dec 5, 2015, 2200 children were enrolled: 1025 at the intervention site and 1175 at the control site. Final analysis included 1021 patients in the CPAP group and 1160 patients in the control group. 2 weeks after enrolment, 26 (3%) of 1021 patients in the CPAP group, and 44 (4%) of 1160 patients in the control group, had died (relative risk [RR] of mortality 0·67, 95% CI 0·42–1·08; p=0·11). In children younger than 1 year, all-cause mortality was ten (3%) of 374 patients in the CPAP group, and 24 (7%) of 359 patients in the control group (RR 0·40, 0·19–0·82; p=0·01). After adjustment for study site, time, and clinically important variables, the odds ratio for 2-week mortality in the CPAP group versus the control group was 0·4 in children aged up to 6 months, 0·5 for children aged 12 months, 0·7 for children aged 24 months, and 1·0 for those aged 36 months. 28 patients (3%) in the CPAP group and 24 patients (2%) in the control group had CPAP-related adverse events, such as vomiting, aspiration, and nasal, skin, or eye trauma. No serious adverse events were observed. Interpretation In the unadjusted analysis the use of CPAP did not decrease all-cause 2-week mortality in children 1 month to 5 years of age with undifferentiated respiratory distress. After adjustment for study site, time, and clinically important variables, 2-week mortality in the CPAP group versus the control group was significantly decreased in children 1 year of age and younger. CPAP is safe and improves respiratory rate in a non-tertiary setting in a lowermiddle- income country

The right to know

Among all everyday choices, food consumption has the largest environmental impact on biodiversity and the global warming. Organizations and politicians have long tried to find a communication strategy to change behavior in this area but with no effect. It is a fact that peoples positive attitude in sustainable living do not match with the actual behavior and that this discrepancy is hard to bridge. The researchers at the Interactive institute believes that the theory of visualizing product information through graphical software and technological tools will help consumers put products in relation to each other and reflect over their consumption and decrease this gap between attitude and behavior. The tools future on the market is questioned and has been investigated and discussed with the executives from Sweden's leading retail chains along with the researchers at the Interactive institute through qualitative research methods. Through the research Its learnd that creating a perfect functioning communication strategy for consumer behavior is not just as easy as finding the most effective one, it also has to be made with the consideration of ethtics and other countries situation

Experimental investigation of tire performance on slush

An investigation of tires behaviour on winter roads was always a high importance in the context of road safety. This paper presents the experimental investigation of tire performance on slush that is identified as two mixtures: a mixture of snow and water, and a mixture of crushed ice and water. The measurements of longitudinal and lateral performance including tire traction, braking and cornering were performed. Tire traction tests were performed for both mixtures with different amount of material. A decreasing in the tire friction was observed when amount of the mixture of snow and water was increased twice. For the mixture of crushed ice and water, an opposite trend was observed. The standard deviation values for the peak force coefficient showed a good reproducibility and reliability of performed tire tests