Pamphlet from Reta Gimple to her school children

A published pamphlet with several poems and printed as a gift from Reta Gimple to her students. The names of the students and the school board are also listed.https://scholars.fhsu.edu/tj_ks_territorial_docs/1043/thumbnail.jp

An Exploration of How Technology Use Influences Outdoor Recreation Choices

The purpose of this research was to determine if there is a need for technology to be accessible to people who visit parks and outdoor recreation sites. An online snowball and hard copy sample of 73 people completed a 29-item questionnaire assessing outdoor activities and the internal and external factors that surround those activities. Visual inspection of the percentage of people involved in each outdoor activity revealed that a majority of the sample population spent their outdoor recreation time hiking, camping and visiting National Parks. A Pearson product-moment correlation revealed that the number of times people participated in these outdoor activities had no correlation to their use of technology. T-test results indicated that how a person feels about their outdoor experience is not affected by whether they use technology. Overall, the study revealed that outdoor recreation choices are not affected by whether a person uses technology or not

EFFECT OF SUPERIMPOSED PRESSURE ON DAMAGE EVOLUTION AND FRACTURE BEHAVIOUR OF AUTOMOTIVE ALUMINUM ALLOYS

This study examined the damage evolution and fracture behaviour oftwo aluminum automotive alloys as a function ofvarious material and testing variables. When applicable, the observations were plotted in stress-strain space in order to construct fracture mechanism maps as functions ofpressure and temperature. The influence ofiron content was examined through the use oftwo different iron contents for each ofthe two alloy systems. For the solution hardened 5754 alloy, it was found that the presence ofincreasing iron content led to more rapid void nucleation, growth and coalescence which produced a decrease in ductility, and change in fracture mode from cup and cone to shear MVC. No change in fracture mode was observed with increasing iron content for the age hardenable 6111 alloy in the T4 temper. However, a decrease in ductility was observed. The Iow-Fe 6111 T6 alloy was found to fail intergranularly, while the high-Fe variant was observed to fail by shear MVC. It was proposed that this was the result ofthe grain refining effects ofthe increased iron content. The evolution of damage was examined by performing uniaxial tensile test under superimposed hydrostatic pressure. In this way, the amount ofdamage generated within the sample during straining could be controlled and its effect on the fracture process examined. The application ofpressure was found to decrease the amount ofdamage present in all samples tested and universally increased the observed ductility. When tested under sufficient pressure, it was found that the 5754 and 6111 T4 alloys would change fracture modes and fail by ductile rupture, with the damage processes suppressedor completely eliminated. Pressure was found to suppress the intergranular fracture mode in the Iow-Fe 6111 alloy, causing a transition to the shear MVC mode offailure. The effect oftemperature on the flow behaviour ofthe 5754 was also examined, as this alloy was found to exhibit the temperature sensitive Portevin Le Chatelier effect. The serrated yielding associated with the effect was found to be greatly reduced testing at 77 K, and grain scale and large scale shear processes within the material were observed to be almost completely eliminated. This was found to lead to large increases in uniform elongation, and a change in fracture mode from cup and cone to shear MVC for the IowFe variant.ThesisMaster of Engineering (ME

Alien Registration- Lerman, Gimple (Portland, Cumberland County)

https://digitalmaine.com/alien_docs/31987/thumbnail.jp

Capacitive Arrays for Robotic Sensing

Electromagnetic arrays have been used effectively for many years in optimizing the responses of antenna systems. The basic principles that make arrayed antennas work and make them easy to control can also be applied to near field electromagnetic array sensors. The array factor allows for flexibility in sensor geometry. Firstly, by exciting only a portion of an array in a sequential fashion one can physically scan and interrogate a region of a sample without having to move the sample or the probe head itself. Secondly, the field configurations can be altered by selectively exciting electrodes of an array. Also, the information received can be selected by combining electrodes to form different effective receiver geometries. Thirdly, array configurations allow for real-time analog signal processing. For instance, one can perform pattern matching by choosing the spatial resolution of the probe to match the spatial resolution of the desired feature

Brain structure in sagittal craniosynostosis

Craniosynostosis, the premature fusion of one or more cranial sutures, leads to grossly abnormal head shapes and pressure elevations within the brain caused by these deformities. To date, accepted treatments for craniosynostosis involve improving surgical skull shape aesthetics. However, the relationship between improved head shape and brain structure after surgery has not been yet established. Typically, clinical standard care involves the collection of diagnostic medical computed tomography (CT) imaging to evaluate the fused sutures and plan the surgical treatment. CT is known to provide very good reconstructions of the hard tissues in the skull but it fails to acquire good soft brain tissue contrast. This study intends to use magnetic resonance imaging to evaluate brain structure in a small dataset of sagittal craniosynostosis patients and thus quantify the effects of surgical intervention in overall brain structure. Very importantly, these effects are to be contrasted with normative shape, volume and brain structure databases. The work presented here wants to address gaps in clinical knowledge in craniosynostosis focusing on understanding the changes in brain volume and shape secondary to surgery, and compare those with normally developing children. This initial pilot study has the potential to add significant quality to the surgical care of a vulnerable patient population in whom we currently have limited understanding of brain developmental outcomes

Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma.

Glioblastoma is the most prevalent primary malignant brain tumor in adults and is characterized by poor prognosis and universal tumor recurrence. Effective glioblastoma treatments are lacking, in part due to somatic mutations and epigenetic reprogramming that alter gene expression and confer drug resistance. To investigate recurrently dysregulated genes in glioblastoma, we interrogated allele-specific expression (ASE), the difference in expression between two alleles of a gene, in glioblastoma stem cells (GSC) derived from 43 patients. A total of 118 genes were found with recurrent ASE preferentially in GSCs compared with normal tissues. These genes were enriched for apoptotic regulators, including schlafen family member 11 (SLFN11). Loss of SLFN11 gene expression was associated with aberrant promoter methylation and conferred resistance to chemotherapy and PARP inhibition. Conversely, low SLFN11 expression rendered GSCs susceptible to the oncolytic flavivirus Zika. This discovery effort based upon ASE revealed novel points of vulnerability in GSCs, suggesting a potential alternative treatment strategy for chemotherapy-resistant glioblastoma. SIGNIFICANCE: Assessing allele-specific expression reveals genes with recurrent cis-regulatory changes that are enriched in glioblastoma stem cells, including SLFN11, which modulates chemotherapy resistance and susceptibility to the oncolytic Zika virus

Expressions 1986

https://openspace.dmacc.edu/expressions/1007/thumbnail.jp