Gaze patterns to child figures reflect deviant sexual preference in child sex offenders: a first glance

Research on non-offending heterosexual participants has indicated that men’s gaze allocation reflects their sexual preference. In this exploratory pilot study we investigated whether naturalistic gaze behaviour is sensitive to deviant sexual preferences. We compared gaze patterns of convicted heterosexual child sex offenders (CSOs; n = 13) with female victims to heterosexual non-offending men (n = 13) in a task of free-viewing images of clothed male and female figures aged 10, 20 and 40 years. CSOs dedicated more fixations to the upper body of the female child than male child figures. The pattern was different for the control sample, whose gaze pattern to male and female figures could only be differentiated when viewing adult figures. CSOs showed significantly greater difference in their gaze towards the upper body of male and female children than non-offenders. Our findings provide preliminary evidence for eye-tracking as a potential method of assessing deviant sexual interest

International Consensus Statement on Rhinology and Allergy: Rhinosinusitis

Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document. Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided. Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS

Association of the 5-HT2c gene with susceptibility and minimum body mass index in anorexia nervosa

The association between a non-conservative Cys23Ser in the 5-HT2c gene and anorexia nervosa in females was examined. We used case-controls and family based association analysis in a sample of 118 patients with DSMIV anorexia nervosa, 244 controls and 47 family trios. There was a significant increase in the frequency of the Ser23 allele in the patients by allele (18.8% vs 12.8%; p = 0.026; OR 1.58, 95% Cl 1.0-2.4) and genotype (32.2% vs 19.9%; genotype-wise p = 0.027). There was significant correlation between genotype and minimum BMI (r(2) = 0.056; p = 0.01), indicating that the Ser23 allele has an effect on severity of illness. We performed TDT analysis using a sub-sample of the cases (58) for whom both parents were available and we found an excess transmission of the Ser23 allele (p = 0.05). Our findings are consistent a role for the Ser23 allele of 5-HT2c in mediating susceptibility to and increasing severity of anorexia nervosa