Statistical evidence of central moment as fault indicators in ball bearing diagnostics

This paper deals with post processing of vibration data coming from a experimental tests. An AC motor running at constant speed is provided with a faulted ball bearing, tests are done changing the type of fault (outer race, inner race and balls) and the stage of the fault (three levels of severity: from early to late stage). A healthy bearing is also measured for the aim of comparison. The post processing simply consists in the computation of scalar quantities that are used in condition monitoring of mechanical systems: variance, skewness and kurtosis. These are the second, the third and the fourth central moment of a real-valued function respectively. The variance is the expectation of the squared deviation of a random variable from its mean, the skewness is the measure of the lopsidedness of the distribution, while the kurtosis is a measure of the heaviness of the tail of the distribution, compared to the normal distribution of the same variance. Most of the papers in the last decades use them with excellent results. This paper does not propose a new fault detection technique, but it focuses on the informative content of those three quantities in ball bearing diagnostics from a statistical point of view. In this paper, a discriminant function analysis is used, to determine which central moment has a high discrimination power in the diagnostics of ball bearing in stationary conditions

Extension of the predictive policy to a series of mechanical systems

In the literature, a great interest is reserved to complex systems (i.e. serial or parallel or mixed systems), constituted by the interconnection of single elements. The evolution of system reliability depends on its structure as well as on the evolution of the reliability of its individual elements. Maintenance activities on systems strongly affect element aging and system\u2019s operating life. Preventive maintenance, for example, is used to increase system availability reducing, as a consequence, the probability of failure. Generally, maintenance plans are performed with respect to some criteria depending on cost or on reliability/availability requirements. Therefore, the optimum maintenance scheduling of a system can be based on the minimization of the total cost or on the maximization of its availability. Many Authors emphasize the requirement on system reliability. In [1], for example, the concept of reliability equivalence from simple series and parallel systems to some complex systems is presented and reliability equivalence factors of complex systems are obtained. One of the most critical problems in preventive maintenance is the determination of the optimum frequency to perform maintenance actions on systems, in order to ensure a pre-defined level of availability. In this paper the predictive maintenance policy, for a single element, is extended to a system constituted by two series elements, named A and B. The transition from a single unit to a series system is not immediate and presents a great number of problems. Actually, when a maintenance action is scheduled for a system of this kind, the decision maker must decide if it is more convenient (with respect to some chosen criterion) to intervene on element A or B or on both. The proposed methodology deals with this practical problem in the context of the predictive maintenance policy. Research on this topic is in a running state and the methodology is only theoretically presented

System monitoring and maintenance policies: a review

In the industrial context, the main goal of the maintenance team is to avoid sudden failures that can cause the stoppage of the system with a consequent loss of production. This means that each maintenance action must be performed before the degradation level of a system exceeds a critical threshold beyond which the failure probability becomes high. The increasing importance given to maintenance is shown not only by the great deal of literature on the topic, but also by the interest in transforming this area from a managerial area to a branch of applied mathematics (Operational Research or Statistics). Maintenance is now considered as a subject and much research activity is concerned with its mathematical modeling rather than with the management processes relating to maintenance itself. In [1], Scarf evidences the great importance of the mathematical modeling of maintenance and the correlated strategic support given by the maintenance management information systems. Nevertheless, no model can be built without an exhaustive collection of data. By data, Author means not only specific figures regarding, for example, failure times, but all information related to the process under study. With the recent advent of condition monitoring and the development of appropriate decision models, critical components of a system can be tracked through appropriate variable(s) correlated to their degradation process, logistic support (for example, spares inventory) can be provided, maintenance history can be stored, predetermined maintenance activity can be alarmed and management reports can be produced. The use of condition monitoring techniques reduces the uncertainty operators feel about the current state of the plant. For example, knowledge about the vibration levels of a rotating bearing gives engineers confidence about its operation in the short term. Data acquired by monitoring systems, maintenance histories collected for specific components can be considered fundamental resources for the mathematical modeling of the maintenance activities. This paper is the first part of two [2], presenting the transition from preventive maintenance policy to the predictive one. In particular, the paper presents a brief review of the subject and some critical considerations about the two maintenance policies

An X-ray polarimeter for hard X-ray optics

Development of multi-layer optics makes feasible the use of X-ray telescope at energy up to 60-80 keV: in this paper we discuss the extension of photoelectric polarimeter based on Micro Pattern Gas Chamber to high energy X-rays. We calculated the sensitivity with Neon and Argon based mixtures at high pressure with thick absorption gap: placing the MPGC at focus of a next generation multi-layer optics, galatic and extragalactic X-ray polarimetry can be done up till 30 keV.Comment: 12 pages, 7 figure

An X-ray Polarimeter for HXMT Mission

The development of micropixel gas detectors, capable to image tracks produced in a gas by photoelectrons, makes possible to perform polarimetry of X-ray celestial sources in the focus of grazing incidence X-ray telescopes. HXMT is a mission by the Chinese Space Agency aimed to survey the Hard X-ray Sky with Phoswich detectors, by exploitation of the direct demodulation technique. Since a fraction of the HXMT time will be spent on dedicated pointing of particular sources, it could host, with moderate additional resources a pair of X-ray telescopes, each with a photoelectric X-ray polarimeter in the focal plane. We present the design of the telescopes and the focal plane instrumentation and discuss the performance of this instrument to detect the degree and angle of linear polarization of some representative sources. Notwithstanding the limited resources the proposed instrument can represent a breakthrough in X-ray Polarimetry.Comment: 10 pages, 9 figure

Heterogeneous effects of spinoff foundations on the means of technology transfer: the role of past academic-industry collaborations

Focusing on the Italian population of academic entrepreneurs, we analyze the effect of establishing a spinoff firm on researchers' attitudes towards carrying out other activities in collaboration with firms, namely, co-publishing and co-patenting. We investigate the heterogeneity in this effect in terms of existing collaborations with firms in the pre-spinoff period. Using a counterfactual analysis on subgroups, we verify that academic entrepreneurs with previous publications with firms diminish their co-publishing and increase their co-patenting after founding a spinoff. Conversely, academic entrepreneurs who had no previous publications with firms increase their co-publishing and decrease their co-patenting. We maintain that such results are related to academics' learning processes connected with their previous technology transfer activities. The policy implications are related to technology transfer aims and contradict the idea that promoting spinoffs is an appropriate "one-size-fits-all" initiative

POLARIX: a pathfinder mission of X-ray polarimetry

Since the birth of X-ray astronomy, spectral, spatial and timing observation improved dramatically, procuring a wealth of information on the majority of the classes of the celestial sources. Polarimetry, instead, remained basically unprobed. X-ray polarimetry promises to provide additional information procuring two new observable quantities, the degree and the angle of polarization. POLARIX is a mission dedicated to X-ray polarimetry. It exploits the polarimetric response of a Gas Pixel Detector, combined with position sensitivity, that, at the focus of a telescope, results in a huge increase of sensitivity. Three Gas Pixel Detectors are coupled with three X-ray optics which are the heritage of JET-X mission. POLARIX will measure time resolved X-ray polarization with an angular resolution of about 20 arcsec in a field of view of 15 arcmin $\times$ 15 arcmin and with an energy resolution of 20 % at 6 keV. The Minimum Detectable Polarization is 12 % for a source having a flux of 1 mCrab and 10^5 s of observing time. The satellite will be placed in an equatorial orbit of 505 km of altitude by a Vega launcher.The telemetry down-link station will be Malindi. The pointing of POLARIX satellite will be gyroless and it will perform a double pointing during the earth occultation of one source, so maximizing the scientific return. POLARIX data are for 75 % open to the community while 25 % + SVP (Science Verification Phase, 1 month of operation) is dedicated to a core program activity open to the contribution of associated scientists. The planned duration of the mission is one year plus three months of commissioning and SVP, suitable to perform most of the basic science within the reach of this instrument.Comment: 42 pages, 28 figure

Safety culture to improve accidental events reporting in radiotherapy

The potential for unintended and adverse radiation exposure in radiotherapy is real and should be studied because radiotherapy is a highly complex, multistep process which requires input from numerous individuals from different areas and steps of the radiotherapy workflow. The 'Incident' (I) is a consequence of which are not negligible from the point of view of protection or safety. A 'near miss' (NM) is defined as an event which is highly likely to happen but did not occur. The purpose of this work is to show that through a systematic reporting and analysis of these adverse events, their occurrence can be reduced

XIPE: the X-ray Imaging Polarimetry Explorer

X-ray polarimetry, sometimes alone, and sometimes coupled to spectral and temporal variability measurements and to imaging, allows a wealth of physical phenomena in astrophysics to be studied. X-ray polarimetry investigates the acceleration process, for example, including those typical of magnetic reconnection in solar flares, but also emission in the strong magnetic fields of neutron stars and white dwarfs. It detects scattering in asymmetric structures such as accretion disks and columns, and in the so-called molecular torus and ionization cones. In addition, it allows fundamental physics in regimes of gravity and of magnetic field intensity not accessible to experiments on the Earth to be probed. Finally, models that describe fundamental interactions (e.g. quantum gravity and the extension of the Standard Model) can be tested. We describe in this paper the X-ray Imaging Polarimetry Explorer (XIPE), proposed in June 2012 to the first ESA call for a small mission with a launch in 2017 but not selected. XIPE is composed of two out of the three existing JET-X telescopes with two Gas Pixel Detectors (GPD) filled with a He-DME mixture at their focus and two additional GPDs filled with pressurized Ar-DME facing the sun. The Minimum Detectable Polarization is 14 % at 1 mCrab in 10E5 s (2-10 keV) and 0.6 % for an X10 class flare. The Half Energy Width, measured at PANTER X-ray test facility (MPE, Germany) with JET-X optics is 24 arcsec. XIPE takes advantage of a low-earth equatorial orbit with Malindi as down-link station and of a Mission Operation Center (MOC) at INPE (Brazil).Comment: 49 pages, 14 figures, 6 tables. Paper published in Experimental Astronomy http://link.springer.com/journal/1068

Synergism Between Immunotherapy and Radiotherapy in Esophageal Cancer: An Overview of Current Knowledge and Future Perspectives

Background: Esophageal cancer (EC) is an aggressive neoplasm of the gastrointestinal tract that is usually treated with a combination of chemotherapy, radiotherapy (RT), and/or surgery, according to disease status. Despite the availability of multimodal therapeutic strategies, local recurrence is frequently observed. Immunotherapy is a promising therapeutic approach that is currently highly investigated in association to standard therapies, including RT, with the aim to improve patients' outcomes. Materials and Methods: A PubMed search was performed with the following keywords in all fields: "esophageal cancer" and "radiotherapy" and "radiation" and "immunotherapy" and "PD-1" and "PD L1." For an overview of ongoing trials, an additional search on ClinicalTrials.gov website was performed using the keywords "esophageal cancer" and "immunotherapy" and "PD-L1" and "CTLA-4" and "radiation" and "radiotherapy." Emerging data from preclinical and clinical studies are suggesting a synergistic effect between immunotherapy and RT. With the aim to update the knowledge of this synergistic immune-mediated antitumor activity and discuss current challenges, the authors summarize published data concerning the basic mechanisms and the effectiveness and tolerance of the combination between immunotherapy and RT for patients with EC, followed by an overview of ongoing clinical trial. Conclusions: Published results encourage the use of personalized therapeutic approaches for EC patients in the future; results from ongoing studies will help to identify the optimal strategies for patient selection and treatment response evaluation