Small bowel obstruction: a recurrence of melanoma during the second trimester of pregnancy

Background: The incidence of melanoma is on the rise in the United States and is particularly prevalent among women of childbearing age. Obtaining a complete history and understanding the unpredictable behavior of melanoma is essential to make the diagnosis of recurrent disease during pregnancy. Case: A 35-year-old G2P1 at 23 weeks and 1 days’ gestation with a remote history of (treated) cutaneous melanoma underwent an exploratory laparotomy for small bowel obstruction. Pathology was consistent with recurrent metastatic melanoma. Conclusion: Metastatic melanoma diagnosed during pregnancy is rare. There are no guidelines on how or when to proceed with treatment of metastatic disease or delivery of the fetus. Immunotherapy is changing the management of melanoma and is extending life expectancy. The significant survival benefits for mother with immunotherapy may outweigh the risks of preterm delivery for the baby

Postpartum contraception acceptance and readiness study

Determine the optimal time to discuss and formulate a plan for postpartum contraception. Determine factors associated with uptake of and adherence to chosen postpartum contraception plan

The impact of time and team on primary cytoreduction outcomes

The degree of cytoreduction at time of initial surgery for epithelial ovarian cancers is correlated with overall survival. Given that surgery can be physically and mentally taxing on the surgeon, we sought to examine if there were temporal and/or team relationships related to primary cytoreduction outcomes

Unique health needs and characteristics of homeless women in Iowa City, Iowa

Context: Homeless individuals have comparatively poorer health, however few gender specific assessments exist. Purpose: This cross-sectional survey of homeless individuals assesses gender-specific health needs. Procedure: 68 Homeless adults were surveyed at a shelter from March to April, 2015 in Iowa City, IA. Descriptive statistics were computed to compare gender-subgroup responses. Main Findings: The study population was predominately male (45, 67.2%), white (37, 54.4%), and averaged 42.35 years old (range 21-74). Males were more likely to be veterans (13, 28.9% vs. 1, 4.5%, p=0.025). Women were more likely to have dependents (9, 47.4% vs. 1, 4%, p=0.001) and access to dental coverage (16, 80% vs. 12, 30.8%, p=0.001). Similar rates of chronic disease, primary care access, and unmet health needs were noted. Conclusions: Homeless women and men have unique needs and would benefit from gender-specific health interventions. Resources for child-care may be important for women who are homeless, while dental health care may be particularly beneficial for men

Thermal Conductivity of Carbon Nanotubes and their Polymer Nanocomposites: A Review

Thermally conductive polymer composites offer new possibilities for replacing metal parts in several applications, including power electronics, electric motors and generators, heat exchangers, etc., thanks to the polymer advantages such as light weight, corrosion resistance and ease of processing. Current interest to improve the thermal conductivity of polymers is focused on the selective addition of nanofillers with high thermal conductivity. Unusually high thermal conductivity makes carbon nanotube (CNT) the best promising candidate material for thermally conductive composites. However, the thermal conductivities of polymer/CNT nanocomposites are relatively low compared with expectations from the intrinsic thermal conductivity of CNTs. The challenge primarily comes from the large interfacial thermal resistance between the CNT and the surrounding polymer matrix, which hinders the transfer of phonon dominating heat conduction in polymer and CNT. This article reviews the status of worldwide research in the thermal conductivity of CNTs and their polymer nanocomposites. The dependence of thermal conductivity of nanotubes on the atomic structure, the tube size, the morphology, the defect and the purification is reviewed. The roles of particle/polymer and particle/particle interfaces on the thermal conductivity of polymer/CNT nanocomposites are discussed in detail, as well as the relationship between the thermal conductivity and the micro- and nano-structure of the composite

Isotopic and chemical assessment of the dynamics of methane sources and microbial cycling during early development of an oil sands pit lake

Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).NSERC (CRDPJ 488301-15) and COSIA; FONDECYT, Grant 11191138 (ANID Chile); COPAS COASTAL ANID, FB210021Peer ReviewedWater-capped tailings technology (WCTT) is a key component of the reclamation strategies in the Athabasca oil sands region (AOSR) of northeastern Alberta, Canada. The release of microbial methane from tailings emplaced within oil sands pit lakes, and its subsequent microbial oxidation, could inhibit the development of persistent oxygen concentrations within the water column, which are critical to the success of this reclamation approach. Here, we describe the results of a four-year (2015–2018) chemical and isotopic (δ13C) investigation into the dynamics of microbial methane cycling within Base Mine Lake (BML), the first full-scale pit lake commissioned in the AOSR. Overall, the water-column methane concentrations decreased over the course of the study, though this was dynamic both seasonally and annually. Phospholipid fatty acid (PLFA) distributions and δ13C demonstrated that dissolved methane, primarily input via fluid fine tailings (FFT) porewater advection, was oxidized by the water column microbial community at all sampling times. Modeling and under-ice observations indicated that the dissolution of methane from bubbles during ebullition, or when trapped beneath ice, was also an important source of dissolved methane. The addition of alum to BML in the fall of 2016 impacted the microbial cycling in BML, leading to decreased methane oxidation rates, the short-term dominance of a phototrophic community, and longer-term shifts in the microbial community metabolism. Overall, our results highlight a need to understand the dynamic nature of these microbial communities and the impact of perturbations on the associated biogeochemical cycling within oil sands pit lakes

Abrupt shifts of productivity and sea ice regimes at the western Barents Sea slope from the Last Glacial Maximum to the Bølling-Allerød interstadial

Advanced knowledge of spatio-temporal constraints on the Barents Sea Ice Sheet during the late Weichselian glaciation overshadows relatively limited understanding of seasonal sea ice (experiencing an annual advance-retreat cycle) and primary productivity trends accompanying massive, abrupt climate changes during glacial-deglacial cycles. Such paleo-reconstructions are crucial prerequisites for improved comprehension and prediction of current and future climate change. Here, we investigate sea ice and phytoplankton biomarker distributions in a Barents Sea sediment core covering ca. 25.8–15.4 cal kyr BP to elucidate abrupt shifts of spring–summer sea ice concentrations and relative sympagic–pelagic productivity trends at the southwestern continental slope. Despite significant presence of seasonal sea ice, the Last Glacial Maximum (LGM) and initial shelf edge deglaciation (SEDG) at the core site are characterised by occurrence of productive coastal polynya adjacent to the maximum ice sheet extent. The onset of perennial (i.e. multi-year) ice cover and near-zero productivity during Heinrich Stadial 1 (HS1; ca. 18.0–16.3 cal kyr BP) accompanies significant meltwater fluxes from ice sheet debuttressing and the consequent stagnation of thermohaline circulation. Rapid sea ice retreat and unprecedented pelagic productivity observed after 16.3 cal kyr BP coincides with areal ice sheet deglaciation and is potentially linked to the release of sub-surface heat and nutrient reservoirs, together with reinvigorated deep water circulation following millennial heating of the deep ocean during HS1. We find that a multivariate fingerprinting approach involving assessment of both downcore and surface biomarker distributions is able to distinguish relative ice-algal and pelagic diatom productivity driven by sea ice dynamics

Adult and juvenile sex identification in threatened monomorphic Geocrinia frogs using fecal steroid analysis

A reliable method for the confirmation of sex in Geocrinia frogs is currently unavailable. A captive colony of Geocrinia frogs was used to determine whether fecal steroid analysis could be used as a noninvasive method of sex diagnosis in mature frogs. Linear discriminate analysis, using measured concentrations of fecal hormones, also was applied to establish whether a reliable model could be developed to verify the sex of juvenile frogs. Fecal samples were collected over a 3-month period from all frogs in 2010, and again from 12 frogs in 2011. Samples were pooled for each individual and tested for testosterone metabolites (TMs) and estrone conjugate metabolites (EMs) using enzyme immunoassays. Mature male frogs had higher (P < 0.01) mean TM : EM ratios than those of mature females, with mature male and female ratio ranges being 100% distinct. Mature female frogs had higher (P < 0.01) mean EM concentrations than those of mature males, but EM concentrations overlapped between the sexes in 18.7% of cases. There was no statistical difference (P = 0.28) between mature males and females in mean or range of TM concentration, with overlap between the sexes in 75% of cases. Juveniles had hormone values similar to those recorded for mature male and female frogs. Generated discriminate rules were able to distinguish (100%) between mature males and females and correctly classified the sex of 75% of the juvenile frogs. It was concluded that fecal steroid analysis offers a promising, noninvasive approach to sex identification in Geocrinia frogs. Copyright 2013 Society for the Study of Amphibians and Reptiles