542 research outputs found

    Author Correction: Task-dependent representations of stimulus and choice in mouse parietal cortex.

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    In the original version of this Article, the Acknowledgements section was inadvertently omitted. This has now been corrected in both the PDF and HTML versions of the Article

    Recruiting Family and Consumer Sciences Volunteers

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    The purpose of the Family and Consumer Sciences (FCS) volunteer program is to build a network of advocates in counties across the state to support Extension FCS programming. This presentation will provide information to Extension FCS educators and program coordinators so they will be able to successfully recruit volunteers in their own county for 2018. The volunteer program recruits volunteers to be advocates, promoters and teachers. We will explain the roles and responsibilities of each type of volunteer and give examples of how volunteers have worked in counties. Information will be provided on how to access the volunteer website, application materials and resources for recruiting, selecting and interviewing of volunteers. Current volunteer supervisors will be sharing success stories from our first 2017 class of volunteers. Expertise of presenters reflect their experience in recruiting, training and partnering with community volunteers.AUTHOR AFFILIATION: Linnette Goard, Family and Consumer Sciences Volunteer Coordinator, The Ohio State University Extension, [email protected] (Corresponding Author); Joanna Fifner, Educator, The Ohio State University Extension; Michelle Treber, Educator, The Ohio State University Extension; Tammy Jones, Educator, The Ohio State University Extension; Shannon Carter, Educator, The Ohio State University Extension.This information is for Extension educators and program coordinators who are interested in recruiting family and consumer sciences volunteers for 2018. Learn about the successes and challenges of the first year and how the process will proceed moving forward. We will share application materials and resources for recruiting, selecting and interviewing potential volunteers. Learn how to navigate the volunteer recruiting process from those who have been successful

    Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD.

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    Hyper-reactivity to sensory input is a common and debilitating symptom in individuals with autism spectrum disorders (ASD), but the neural basis underlying sensory abnormality is not completely understood. Here we examined the neural representations of sensory perception in the neocortex of a Shank3B-/- mouse model of ASD. Male and female Shank3B-/- mice were more sensitive to relatively weak tactile stimulation in a vibrissa motion detection task. In vivo population calcium imaging in vibrissa primary somatosensory cortex (vS1) revealed increased spontaneous and stimulus-evoked firing in pyramidal neurons but reduced activity in interneurons. Preferential deletion of Shank3 in vS1 inhibitory interneurons led to pyramidal neuron hyperactivity and increased stimulus sensitivity in the vibrissa motion detection task. These findings provide evidence that cortical GABAergic interneuron dysfunction plays a key role in sensory hyper-reactivity in a Shank3 mouse model of ASD and identify a potential cellular target for exploring therapeutic interventions

    UNCONDITIONAL FORGIVINGNESS

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    In the last few decades, some scholars have questioned the moral value of forgiveness. They have argued that in order for a victim to preserve his self-respect, to not condone the wrongdoing, and to avoid unjustly pardoning the offender, he must consider forgiving only after the offender has satisfied specific conditions that have been demanded of him. Forgiveness, they claim, is morally permissible only when it is given conditionally. Unconditional forgiveness cannot be virtuous. This dissertation addresses the issues surrounding this claim. I argue that Forgivingness, which is the virtue associated with forgiving, causes its possessor to reliably offer unconditional forgiveness to every person who offends him. Further, I contend that instances of forgiveness, arising from or contributing to the development of this virtue, are never morally impermissible even though their moral quality may not be ideal. To support my thesis, I develop a model of Forgivingness that represents it as a multi-faceted virtue of cognitive, affective, motivational, and action components that, independently of the actions and attitudes of the offender, produce unilateral, unconditional forgiveness. I describe Forgivingness’s dependency on the characteristic of moral love—a quality that values an offender’s ultimate moral good and ideal self, displays good will towards him, and assimilates the virtue of self-forgetfulness into the possessor’s deliberations, desires, and actions—and explain the virtue’s relationship to ancillary or homologous emotions including hope, humility, magnanimity, and anger. I then defend the forgiveness that multi-faceted Forgivingness produces against criticisms that are commonly levied against unconditional forgiveness. In doing so, I reinforce a theme that runs throughout the entire work—that is, that virtuous forgiveness is distinct from minimal forgiveness. When relevant, I show the weaknesses in minimal forgiveness so as to emphasize the moral strength and beauty of virtuous forgiveness. Further, I distinguish virtuous forgiveness from forgetting, reconciliation, and excuse-making and explain how it can be compatible with disciplining the offender. Consequently, I demonstrate why virtuous forgiveness that is given according to my model of the virtue is immune to the criticisms that may be relevant to other forms of forgiveness

    Theology and Reality: Critical Realism in the Thought of Alister E. McGrath

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    Brian Lee Goard, Ph.D. The Southern Baptist Theological Seminary, 2011 Chairperson: Dr. Gregg R. Allison This dissertation examines the role of critical realism in the theological method of Alister E. McGrath. The thesis of the dissertation is that Alister McGrath uses critical realism in a way that strengthens his theological method and that serves a number of good theological ends, yet McGrath's methodology is in need of revision in some areas, and clarification in others, if it is going to be theologically acceptable. Chapter 1 introduces (1) the philosophy of critical realism, (2) Alister McGrath's work in theological method, and (3) the thesis and methodology of the dissertation. Chapter 2 examines the history and development of critical realism, beginning with the work of Roy Wood Sellars in the early twentieth century and concluding with a description of critical realism as developed by Roy Bhaskar. Chapter 2 argues that historically, critical realism has been a versatile method that can be applied to a variety of projects and disciplines. Chapter 3 delineates the main themes of McGrath's methodology and how critical realism affects those areas. Specific points addressed in this chapter include McGrath's prolonged engagement with other theological methodologies (chief among them being postliberalism), the concept of nature, natural theology, and the science-theology dialogue. Chapter 4 provides a critical evaluation of McGrath's use of critical realism. A number of positive conclusions about McGrath's use of critical realism are drawn, yet where McGrath has made problematic or underdeveloped applications of critical realism, both correction and suggestions for further development are offered. Finally, chapter 5 reviews the thesis of the dissertation and considers the method that has been taken in defense of that thesis. Specifically, it demonstrates how each of the previous chapters serve as evidence for the dissertation's thesis

    Stochastic volatility models and the pricing of VIX options

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    In this paper we examine and compare the performance of a variety of continuous- time volatility models in their ability to capture the behaviour of the VIX. The `3/2- model\u27 with a di®usion structure which allows the volatility of volatility changes to be highly sensitive to the actual level of volatility is found to outperform all other popular models tested. Analytic solutions for option prices on the VIX under the 3/2- model are developed and then used to calibrate at-the-money market option prices
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