Patient Lifecycle Management: An Approach for Clinical Processes

Clinical processes can be described, inside the Biomedical scope, like a systematic guideline to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances. In industry, Product Lifecycle Management (PLM) is the process of managing the entire lifecycle of a product from inception, through engineering design and manufacture, to service and disposal of manufactured products. Applying the concepts of PLM to Biomedical processes we create a synergy between the product’s concept in the industrial case and the patient into the health care environment. This point of view improves the actual clinical processes with a most specific treatment for each patient, by modifying the statements to assist the patient according to the needs of the patient and his illness. This research proposal tries to shift the focus of the eHealth systems onto the patient, adapts the existing and defined clinical processes or clinical paths to the patient’s needs, applies Big Data principles to bring even more attentions for the patient, and provides an easy to use system for the medical staff.Ministerio de Economía y Competitividad TIN2013-46928-C3-3-RMinisterio de Economía y Competitividad TIN2014-52382-

Greenes Restaurant Cork A La Carte Menu 2017

The food at Greenes is innovative, modern and devoted to place. Bryan McCarthy heads up the kitchen team at Greenes and recognises the uniqueness and quality of the outstanding ingredients that are available in Cork. His talented team works in tandem with the best of Cork’s food producers and in other parts of Ireland to create a menu that’s devoted to local, seasonal, foraged and organic ingredients. Expect signature dishes of a seasonal nature, refined food with a simple food philosophy - local, fresh and staying true to each ingredient’s essence. Traditional food practices, such as pickling and fermenting, together with innovative techniques, as well as quality, sustainable meat and fish, and locally sourced organic vegetables and herbs, have transformed Greenes into the destination restaurant that it is today. Greenes is located in a former bonded warehouse in Cork’s historic Victorian Quarter in the centre of the city.https://arrow.tudublin.ie/menus21c/1356/thumbnail.jp

Greenes Restaurant Cork Pre Theatre Menu 2017

The food at Greenes is innovative, modern and devoted to place. Bryan McCarthy heads up the kitchen team at Greenes and recognises the uniqueness and quality of the outstanding ingredients that are available in Cork. His talented team works in tandem with the best of Cork’s food producers and in other parts of Ireland to create a menu that’s devoted to local, seasonal, foraged and organic ingredients. Expect signature dishes of a seasonal nature, refined food with a simple food philosophy - local, fresh and staying true to each ingredient’s essence. Traditional food practices, such as pickling and fermenting, together with innovative techniques, as well as quality, sustainable meat and fish, and locally sourced organic vegetables and herbs, have transformed Greenes into the destination restaurant that it is today. Greenes is located in a former bonded warehouse in Cork’s historic Victorian Quarter in the centre of the city.https://arrow.tudublin.ie/menus21c/1358/thumbnail.jp

Greenes Restaurant Cork Lunch Menu

The food at Greenes is innovative, modern and devoted to place. Bryan McCarthy heads up the kitchen team at Greenes and recognises the uniqueness and quality of the outstanding ingredients that are available in Cork. His talented team works in tandem with the best of Cork’s food producers and in other parts of Ireland to create a menu that’s devoted to local, seasonal, foraged and organic ingredients. Expect signature dishes of a seasonal nature, refined food with a simple food philosophy - local, fresh and staying true to each ingredient’s essence. Traditional food practices, such as pickling and fermenting, together with innovative techniques, as well as quality, sustainable meat and fish, and locally sourced organic vegetables and herbs, have transformed Greenes into the destination restaurant that it is today. Greenes is located in a former bonded warehouse in Cork’s historic Victorian Quarter in the centre of the city.https://arrow.tudublin.ie/menus21c/1357/thumbnail.jp

Greenes Restaurant Cork Tasting Menu 2017

The food at Greenes is innovative, modern and devoted to place. Bryan McCarthy heads up the kitchen team at Greenes and recognises the uniqueness and quality of the outstanding ingredients that are available in Cork. His talented team works in tandem with the best of Cork’s food producers and in other parts of Ireland to create a menu that’s devoted to local, seasonal, foraged and organic ingredients. Expect signature dishes of a seasonal nature, refined food with a simple food philosophy - local, fresh and staying true to each ingredient’s essence. Traditional food practices, such as pickling and fermenting, together with innovative techniques, as well as quality, sustainable meat and fish, and locally sourced organic vegetables and herbs, have transformed Greenes into the destination restaurant that it is today. Greenes is located in a former bonded warehouse in Cork’s historic Victorian Quarter in the centre of the city.https://arrow.tudublin.ie/menus21c/1359/thumbnail.jp

Intuitive and Informal Knowledge in Preschoolers’ Development of Probabilistic Thinking

Preschoolers develop a wide range of mathematical informal knowledge and intuitive thinking before they enter formal, goal-oriented education. In their everyday activities young children get engaged with situations that enhance them to develop skills, concepts, strategies, representations, attitudes, constructs and operations concerning a wide range of mathematical notions. Recently there is scientific interest in linking children’s informal and formal knowledge in order to provide them with opportunities to avoid biases aiming at formulating, perceiving, reflecting on and exercising probabilistic notions. The current study investigates preschoolers’ (N=90) intuitive understanding of the likelihood of events in a probabilistic task with spinners. Participants, at the age of 4 to 6, are tested on their predictions of the most probable outcome prior to and after an instructive session of reasoning. The probabilistic task, based on constructivist principles, includes methodological alterations concerning the sample space and the themes of the stimuli. Educational implications are further discussed under the general point of view that in order to link informal to formal mathematical learning in preschool classroom, the subject content and the cognitive capacity of children are important to match

Knowledge Infrastructure Requirements for Computable Biomedical Knowledge (CBK)

Purpose: Platforms for computable biomedical knowledge are rapidly emerging to accelerate the application of biomedical knowledge into practice. At an inaugural Mobilizing Computable Biomedical Knowledge (MCBK) working meeting held in Ann Arbor, MI on October 18 & 19, 2017, the group took important early steps to: Engage critical dialogue on how to effectively develop and govern platforms for machine-executable biomedical knowledge to improve health and to build a pre-competitive computable biomedical knowledge community. This conference was significant for advancing work in areas that require computable knowledge to translate biomedical insights for better health: Learning Health Systems, Open Biomedical Science, and Clinical Decision Support. Participants explored what will be required to shape and sustain a community focused on making computable biomedical knowledge FAIR: Findable, Accessible, Interoperable and Reusable. Participants discussed biomedical computable knowledge in the context of four, overarching themes, one of which included Knowledge Infrastructure Requirements for Computable Biomedical Knowledge.https://deepblue.lib.umich.edu/bitstream/2027.42/140738/1/Knowledge Infrastructure Requirements for Computable Biomedical Knowledge (CBK) Briefing Paper.pdf-1Description of Knowledge Infrastructure Requirements for Computable Biomedical Knowledge (CBK) Briefing Paper.pdf : Briefing Pape

Prevalence of Brain Injuries and Recurrence of Seizures in Children With Posttraumatic Seizures

ObjectivesComputed tomography (CT) is often used in the emergency department (ED) evaluation of children with posttraumatic seizures (PTS); however, the frequency of traumatic brain injuries (TBIs) and short‐term seizure recurrence is lacking. Our main objective was to evaluate the frequency of TBIs on CT and short‐term seizure recurrence in children with PTS. We also aimed to determine the associations between the likelihood of TBI on CT with the timing of onset of PTS after the traumatic event and duration of PTS. Finally, we aimed to determine whether patients with normal CT scans and normal neurological examinations are safe for discharge from the ED.MethodsThis was a planned secondary analysis from a prospective observational cohort study to derive and validate a neuroimaging decision rule for children after blunt head trauma at 25 EDs in the Pediatric Emergency Care Applied Research Network. We evaluated children < 18 years with head trauma and PTS between June 2004 and September 2006. We assessed TBI on CT, neurosurgical interventions, and recurrent seizures within 1 week. Patients discharged from the ED were contacted by telephone 1 week to 3 months later.ResultsOf 42,424 children enrolled, 536 (1.3%, 95% confidence interval [CI] = 1.2%–1.4%) had PTS. A total of 466 of 536 (86.9%, 95% CI = 83.8%–89.7%) underwent CT in the ED. TBIs on CT were identified in 72 (15.5%, 95% CI = 12.3%–19.1%), of whom 20 (27.8%, 95% CI = 17.9%–39.6%) underwent neurosurgical intervention and 15 (20.8%, 95% CI = 12.2%–32.0%) had recurrent seizures. Of the 464 without TBIs on CT (or no CTs performed), 457 had recurrent seizure status known, and five (1.1%, 95 CI = 0.4%–2.5%) had recurrent seizures; four of five presented with Glasgow Coma Scale scores < 15. None of the 464 underwent neurosurgical intervention. We found significant associations between likelihood of TBI on CT with longer time until the PTS after the traumatic event (p = 0.006) and longer duration of PTS (p < 0.001).ConclusionsChildren with PTS have a high likelihood of TBI on CT, and those with TBI on CT frequently require neurosurgical interventions and frequently have recurrent seizures. Those without TBIs on CT, however, are at low risk of short‐term recurrent seizures, and none required neurosurgical interventions. Therefore, if CT‐negative and neurologically normal, patients with PTS may be safely considered for discharge from the ED.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137424/1/acem13168.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/137424/2/acem13168_am.pd

Summary of second annual MCBK public meeting: Mobilizing Computable Biomedical Knowledge—A movement to accelerate translation of knowledge into action

The volume of biomedical knowledge is growing exponentially and much of this knowledge is represented in computer executable formats, such as models, algorithms and programmatic code. There is a growing need to apply this knowledge to improve health in Learning Health Systems, health delivery organizations, and other settings. However, most organizations do not yet have the infrastructure required to consume and apply computable knowledge, and national policies and standards adoption are not sufficient to ensure that it is discoverable and used safely and fairly, nor is there widespread experience in the process of knowledge implementation as clinical decision support. The Mobilizing Computable Biomedical Knowledge (MCBK) community formed in 2016 to address these needs. This report summarizes the main outputs of the Second Annual MCBK public meeting, which was held at the National Institutes of Health on July 18‐19, 2019 and brought together over 150 participants from various domains to frame and address important dimensions for mobilizing CBK.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154970/1/lrh2-sup-0001-supinfo.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154970/2/lrh210222.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154970/3/lrh210222_am.pd

A study of collaboration among medical informatics research laboratories

Abstract The InterMed Collaboratory involves five medical institutions (Stanford University, Columbia University, Brigham and Women&apos;s Hospital, Massachusetts General Hospital, and McGill University) whose mandate has been to join in the development of shared infrastructural software, tools, and system components that will facilitate and support the development of diverse, institution-specific applications. Collaboration among geographically distributed organizations with different goals and cultures provides significant challenges. One experimental question, underlying all that InterMed has set out to achieve, is whether modern 0933-3657/98/$19.00 © 1998 Elsevier Science B.V. All rights reserved. PII S 0 9 3 3 -3 6 5 7 ( 9 7 ) 0 0 0 4 5 -6 12 (1998) 97-123 98 communication technologies can effectively bridge such cultural and geographical gaps, allowing the development of shared visions and cooperative activities so that the end results are greater than any one group could have accomplished on its own. In this paper we summarize the InterMed philosophy and mission, describe our progress over 3 years of collaborative activities, and present study results regarding the nature of the evolving collaborative processes, the perceptions of the participants regarding those processes, and the role that telephone conference calls have played in furthering project goals. Both informal introspection and more formal evaluative work, in which project participants became subjects of study by our evaluation experts from McGill, helped to shift our activities from relatively unfocused to more focused efforts while allowing us to understand the facilitating roles that communications technologies could play in our activities. Our experience and study results suggest that occasional face-to-face meetings are crucial precursors to the effective use of distance communications technologies; that conference calls play an important role in both task-related activities and executive (project management) activities, especially when clarifications are required; and that collaborative productivity is highly dependent upon the gradual development of a shared commitment to a well-defined task that leverages the varying expertise of both local and distant colleagues in the creation of tools of broad utility across the participating sites. E.H. Shortliffe et al. / Artificial Intelligence in Medicin